Protein Alignment Sply and Sgpl1

DIOPT Version :10

• Sequence 1: NP_652032.1
• Gene: Sply / 46059
• FlyBaseID: FBgn0010591
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_033189.2
• Gene: Sgpl1 / 20397
• MGIID: 1261415
• Length: 568
• Species: Mus musculus
• Alignment Length: 554
• Identity: 266/554 - (48%)
• Similarity: 372/554 - (67%)
• Gaps: 22/554 - (3%)

  Fly     6 GSDCLK-----PVTEGINRAFGAK------------EPWQVATITATTVLGGVWLWTVICQDENL 53
            |:|.||     |..| |..::..|            ||||:...:....|..||::.:|.|.|:|
Mouse     3 GTDLLKLKDFEPYLE-ILESYSTKAKNYVNGYCTKYEPWQLIAWSVLCTLLIVWVYELIFQPESL 66

  Fly    54 YIRGKRQFFKFAKKIPAVRRQVETELAKAKNDFETEIKKSNAHLTYSETLPEKGLSKEEILRLVD 118
            :.|.|::.||..:|:|.:.|::|.:::|||.|....:........|.:|||.:|:...|:|..:.
Mouse    67 WSRFKKKLFKLIRKMPFIGRKIEQQVSKAKKDLVKNMPFLKVDKDYVKTLPAQGMGTAEVLERLK 131

  Fly   119 EHLKTGHYNWRDGRVSGAVYGYKPDLVELVTEVYGKASYTNPLHADLFPGVCKMEAEVVRMACNL 183
            |: .:...:|::|:.|||||..:|.|.||:.:.||:.:::||||.|:|||:.|:|||:|||.|:|
Mouse   132 EY-SSMDGSWQEGKASGAVYNGEPKLTELLVQAYGEFTWSNPLHPDIFPGLRKLEAEIVRMTCSL 195

  Fly   184 FHGNSASCGTMTTGGTESIVMAMKAYRDFAREYKGITRPNIVVPKTVHAAFDKGGQYFNIHVRSV 248
            |:|...|||.:|:||||||:||.|||||.|.| |||..|.||.|::.||||||...||.:.:..|
Mouse   196 FNGGPDSCGCVTSGGTESILMACKAYRDLALE-KGIKTPEIVAPESAHAAFDKAAHYFGMKIVRV 259

  Fly   249 DVDPETYEVDIKKFKRAINRNTILLVGSAPNFPYGTIDDIEAIAALGVKYDIPVHVDACLGSFVV 313
            .: .:..|||::..||||:|||.:||.|.|.||:|.:|.:..:|.|.|:|.||:|||||||.|::
Mouse   260 AL-KKNMEVDVQAMKRAISRNTAMLVCSTPQFPHGVMDPVPEVAKLAVRYKIPLHVDACLGGFLI 323

  Fly   314 ALVRNAGYKL-RPFDFEVKGVTSISADTHKYGFAPKGSSVILYSDKKYKDHQFTVTTDWPGGVYG 377
            ..:..|||.| :||||.|||||||||||||||:|||||||::||::||:.:||.|..||.||||.
Mouse   324 VFMEKAGYPLEKPFDFRVKGVTSISADTHKYGYAPKGSSVVMYSNEKYRTYQFFVGADWQGGVYA 388

  Fly   378 SPTVNGSRAGGIIAACWATMMSFGYDGYLEATKRIVDTARYIERGVRDIDGIFIFGKPATSVIAL 442
            ||::.|||.|||||||||.:|.||.:||:||||:|:.|||:::..:.:|..|||||.|..|||||
Mouse   389 SPSIAGSRPGGIIAACWAALMHFGENGYVEATKQIIKTARFLKSELENIKNIFIFGDPQLSVIAL 453

  Fly   443 GSNVFDIFRLSDSLCKLGWNLNALQFPSGIHLCVTDMHTQPGVADKFIADVRSCTAEIMKDPGQP 507
            |||.|||:|||:.:...|||.|.||||..||.|:|.:||:..||.:|:.|:|....:|||:|...
Mouse   454 GSNDFDIYRLSNMMSAKGWNFNYLQFPRSIHFCITLVHTRKRVAIQFLKDIRESVTQIMKNPKAK 518

  Fly   508 VVGKMALYGMAQSIPDRSVIGEVTRLFLHSMYYT 541
            ..|..|:|||||:..||.::.|::.:||..:|.|
Mouse   519 TTGMGAIYGMAQATIDRKLVAEISSVFLDCLYTT 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sply	NP_652032.1	DOPA_deC_like	132..494	CDD:99743	206/362 (57%)
Sgpl1	NP_033189.2	DOPA_deC_like	146..507	CDD:99743	207/362 (57%)