Protein Alignment Sply and Gad2

DIOPT Version :9

• Sequence 1: NP_652032.1
• Gene: Sply / 46059
• FlyBaseID: FBgn0010591
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_032104.2
• Gene: Gad2 / 14417
• MGIID: 95634
• Length: 585
• Species: Mus musculus
• Alignment Length: 429
• Identity: 89/429 - (20%)
• Similarity: 165/429 - (38%)
• Gaps: 82/429 - (19%)

  Fly    57 GKRQFFKFAKKIPAVRRQVETELAKAKNDFETEIKKSNAHL------TYSETLPEKGLSKEEIL- 114
            |:|....|.:.:..:..|...:      .|:...|..:.|.      .|:..|.::..:.||||
Mouse   103 GERPTLAFLQDVMNILLQYVVK------SFDRSTKVIDFHYPNELLQEYNWELADQPQNLEEILT 161

  Fly   115 ---RLVDEHLKTGHYNWRDGRVSGAVYGYKPDLVELVTEVYGKASYTNPLHADLFPGVCKMEAEV 176
               ..:...:||||..:.:...:|.      |:|.|..:.....:.||....::.|....:|...
Mouse   162 HCQTTLKYAIKTGHPRYFNQLSTGL------DMVGLAADWLTSTANTNMFTYEIAPVFVLLEYVT 220

  Fly   177 VRMACNL--FHGNSASCGTMTTGGTESIVMAM--KAYRDFAR-EYKGITR-PNIVVPKTVHAAFD 235
            ::....:  :.|.|.. |..:.||..|.:.||  ..|:.|.. :.||:.. |.::...:.|:.|.
Mouse   221 LKKMREIIGWPGGSGD-GIFSPGGAISNMYAMLIARYKMFPEVKEKGMAAVPRLIAFTSEHSHFS 284

  Fly   236 --KGGQYFNIHVRSV--------------DVDPETYEVDIKKFKRAINRNTILLVGSAPNFPYGT 284
              ||.....|...||              |::....||..|.|.      ..|:..:|....||.
Mouse   285 LKKGAAALGIGTDSVILIKCDERGKMIPSDLERRILEVKQKGFV------PFLVSATAGTTVYGA 343

  Fly   285 IDDIEAIAALGVKYDIPVHVDACLGSFVVALVRNAGYKLRPFDFEVKGVTSISADTHKYGFAPKG 349
            .|.:.|:|.:..||.|.:||||..|..:: :.|...:||.    .|:...|::.:.||....|..
Mouse   344 FDPLLAVADICKKYKIWMHVDAAWGGGLL-MSRKHKWKLS----GVERANSVTWNPHKMMGVPLQ 403

  Fly   350 SSVILYSDK-----------KY---KDHQFTVTTDWPGGVYGSPTVNGSRAGGI--IAACWATMM 398
            .|.:|..::           .|   :|..:.::.|     .|...:...|...:  :...|....
Mouse   404 CSALLVREEGLMQSCNQMHASYLFQQDKHYDLSYD-----TGDKALQCGRHVDVFKLWLMWRAKG 463

  Fly   399 SFGYDGYLEATKRIVDTARYIERGVRDIDGI-FIF-GKP 435
            :.|::.:::   :.::.|.|:...:::.:|. .:| |||
Mouse   464 TTGFEAHID---KCLELAEYLYTIIKNREGYEMVFDGKP 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sply	NP_652032.1	DOPA_deC_like	132..494	CDD:99743	72/344 (21%)
Gad2	NP_032104.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24
		Pyridoxal_deC	138..509	CDD:278699	82/388 (21%)
		Substrate binding. /evidence=ECO:0000250	181..183		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810