Protein Alignment Sply and Gad1

DIOPT Version :9

• Sequence 1: NP_652032.1
• Gene: Sply / 46059
• FlyBaseID: FBgn0010591
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_032103.2
• Gene: Gad1 / 14415
• MGIID: 95632
• Length: 593
• Species: Mus musculus
• Alignment Length: 517
• Identity: 104/517 - (20%)
• Similarity: 175/517 - (33%)
• Gaps: 148/517 - (28%)

  Fly    57 GKRQFFKFAKKIPAVRRQVETELAKAKNDFETEIKKSNAHLT---------YSETLPEKGLSKEE 112
            |:.|..:|..::      |:..|...:..|:...|..:.|..         ::..|.:...|.|:
Mouse   108 GEEQTAQFLLEV------VDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQ 166

  Fly   113 ILRLVDEHLK----TGHYNWRDGRVSGAVYGYKPDLVELVTEVYGKASYTNPLHADLFPGVCKME 173
            ||....:.||    |||..:.:...:|.      |::.|..|.....:.||....::.|....||
Mouse   167 ILVDCRDTLKYGVRTGHPRFFNQLSTGL------DIIGLAGEWLTSTANTNMFTYEIAPVFVLME 225

  Fly   174 -------AEVVRMACNLFHGNSASCGTMTTGGTESIVMAMKAYR-DFAREYKGITRPNIVVPKTV 230
                   .|:|..:      |....|..:.||..|.:.::.|.| .:..|.|  |:....|||.|
Mouse   226 QITLKKMREIVGWS------NKDGDGIFSPGGAISNMYSIMAARYKYFPEVK--TKGMAAVPKLV 282

  Fly   231 -------HAAFDKGGQYF------------NIHVRSVDVDPETYEVDIKK------FKRAINRNT 270
                   |.:..|.|...            |...:.:..|.|...:|.|:      :..|....|
Mouse   283 LFTSEHSHYSIKKAGAALGFGTDNVILIKCNERGKIIPADLEAKILDAKQKGYVPLYVNATAGTT 347

  Fly   271 ILLVGSAPNFPYGTIDDIEAIAALGVKYDIPVHVDACLGSFVVALVRNAGYKLRPFDFEVKGVTS 335
            :          ||..|.|:.||.:..||::.:||||..|.                     |:..
Mouse   348 V----------YGAFDPIQEIADICEKYNLWLHVDAAWGG---------------------GLLM 381

  Fly   336 ISADTHKYGFAPKGSSVILYSDKKYKDHQFTVTTDWPGGVYGSPTVNGSRAGGIIAACWATMMSF 400
            .....||.....:.:||                           |.|..:..|::..|.|.::.
Mouse   382 SRKHRHKLSGIERANSV---------------------------TWNPHKMMGVLLQCSAILVK- 418

  Fly   401 GYDGYLEATKRIVDTARYIERGVRDIDGIFIFGKPATSVIALGSNVFDIFRLSDSLCKLGWNL-N 464
             ..|.|:...::  .|.|:.:..:..|..:..|..|   |..|.:| |||:.     .|.|.. .
Mouse   419 -EKGILQGCNQM--CAGYLFQPDKQYDVSYDTGDKA---IQCGRHV-DIFKF-----WLMWKAKG 471

  Fly   465 ALQFPSGIHLCVTDMHTQPGVADKFIADVRSCTAEIMKDPGQPVVGKMALYGMAQS---IPD 523
            .:.|.:.|:.|:.       :||...|.:::.....|...|:|....:..:.:.||   :||
Mouse   472 TVGFENQINKCLE-------LADYLYAKIKNREEFEMVFDGEPEHTNVCFWYIPQSLRGVPD 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sply	NP_652032.1	DOPA_deC_like	132..494	CDD:99743	79/395 (20%)
Gad1	NP_032103.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22
		Pyridoxal_deC	143..517	CDD:365998	92/465 (20%)
		Substrate binding. /evidence=ECO:0000250	189..191		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900