DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta1 and PSMB9

DIOPT Version :9

Sequence 1:	NP_652031.2	Gene:	Prosbeta1 / 46058	FlyBaseID:	FBgn0010590	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_002791.1	Gene:	PSMB9 / 5698	HGNCID:	9546	Length:	219	Species:	Homo sapiens

Alignment Length:	204	Identity:	107/204 - (52%)
Similarity:	137/204 - (67%)	Gaps:	5/204 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DTP----VSTGTTIMAVEFDGGVVIGADSRTSSGAYVANRVTDKLTRITDKVYCCRSGSAADTQA 69
            |.|    |.|||||||||||||||:|:|||.|:|..|.|||.|||:.:.:::||..||||||.||
Human    10 DLPRAGEVHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQA 74

  Fly    70 IADIVAYSLNYHENQTNKDALVFEAASEFRNYCYSYRESLLAGIIVAGWDEQRGGQVYSIPLGGM 134
            :||:.||.|..|..:..:..||..||:..||..|.|||.|.|.::|||||::.|||||. .||||
Human    75 VADMAAYQLELHGIELEEPPLVLAAANVVRNISYKYREDLSAHLMVAGWDQREGGQVYG-TLGGM 138

  Fly   135 LTRESCTIGGSGSSFIYGFVREHYRPNMALEDCVTFVKKAVQHAIYHDGSSGGVVRIGIITKDGI 199
            |||:...||||||:||||:|...|:|.|:.|:|..|...|:..|:..|||||||:.:..||..|:
Human   139 LTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVIYLVTITAAGV 203

  Fly   200 ERRIFYNTE 208
            :.|:....|
Human   204 DHRVILGNE 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta1	NP_652031.2	20S_bact_beta	15..201	CDD:163402	101/185 (55%)
Prosbeta1	NP_652031.2	proteasome_beta_type_6	16..203	CDD:239731	100/186 (54%)
PSMB9	NP_002791.1	proteasome_beta_type_6	21..207	CDD:239731	100/186 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165142921
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0174
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54145
OrthoDB	1	1.010	-	-		D1172133at2759
OrthoFinder	1	1.000	-	-		FOG0001868
OrthoInspector	1	1.000	-	-		otm40301
orthoMCL	1	0.900	-	-		OOG6_101390
Panther	1	1.100	-	-	O	PTHR11599
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1014
SonicParanoid	1	1.000	-	-		X1224
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.750