DRSC/TRiP Functional Genomics Resources

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Protein Alignment Prosbeta1 and PSMB4

DIOPT Version :10

Sequence 1:NP_652031.2 Gene:Prosbeta1 / 46058 FlyBaseID:FBgn0010590 Length:224 Species:Drosophila melanogaster
Sequence 2:NP_002787.2 Gene:PSMB4 / 5692 HGNCID:9541 Length:264 Species:Homo sapiens


Alignment Length:237 Identity:50/237 - (21%)
Similarity:85/237 - (35%) Gaps:83/237 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 TDTPVSTGTTIMAVEFDGGVVIGADSRTSSGAYVANRVTDKLTRITDKVYCCRSGSAADTQAIAD 72
            |..|:.|||:::.|:|:|||||.||...|.|:....|...::.|:.:......||..||      
Human    46 TQNPMVTGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYAD------ 104

  Fly    73 IVAYSLNYHENQTNKDALVFEAASEFRNYCYSYRESLLAGIIVAGWDEQRGGQVYSI---PLGGM 134
                                          :.|.:.:|..:::   ||:..|..:|.   .:...
Human   105 ------------------------------FQYLKQVLGQMVI---DEELLGDGHSYSPRAIHSW 136

  Fly   135 LTR-------------ESCTIGG--SGSSFI------------------YG------FVRE--HY 158
            |||             .:..|||  .|.||:                  ||      .:||  ..
Human   137 LTRAMYSRRSKMNPLWNTMVIGGYADGESFLGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEK 201

  Fly   159 RPNMALEDCVTFVKKAVQHAIYHDGSSGGVVRIGIITKDGIE 200
            :|.::..:....|::.::...|.|..|....:|..:|:.|:|
Human   202 QPVLSQTEARDLVERCMRVLYYRDARSYNRFQIATVTEKGVE 243

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Prosbeta1NP_652031.2 proteasome_beta_type_6 16..203 CDD:239731 46/229 (20%)
PSMB4NP_002787.2 proteasome_beta_type_4 52..247 CDD:239729 48/231 (21%)

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