DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta1 and pbs-1

DIOPT Version :9

Sequence 1:	NP_652031.2	Gene:	Prosbeta1 / 46058	FlyBaseID:	FBgn0010590	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_500125.2	Gene:	pbs-1 / 176978	WormBaseID:	WBGene00003947	Length:	242	Species:	Caenorhabditis elegans

Alignment Length:	208	Identity:	103/208 - (49%)
Similarity:	149/208 - (71%)	Gaps:	1/208 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 VSTGTTIMAVEFDGGVVIGADSRTSSGAYVANRVTDKLTRITDKVYCCRSGSAADTQAIADIVAY 76
            :|||||::|:|::||||:|.|||||:|:::.:|.|:|:|.|||.:..|||||||||||||||..|
Worm    23 ISTGTTLIAMEYNGGVVVGTDSRTSAGSFITSRATNKITPITDNMVVCRSGSAADTQAIADIAKY 87

  Fly    77 SLNYHENQTNKDALVFEAASEFRNYCYSYRESLLAGIIVAGWDEQRGGQVYSIPLGGMLTRESCT 141
            .::.:....||...::.::..||.:.|:|||.|.|.::||||||:.|||||:||:||.::|:..|
Worm    88 HIDVYTMTENKPVTIYRSSQIFRQFLYNYREQLSASVLVAGWDEELGGQVYAIPIGGFVSRQRST 152

  Fly   142 IGGSGSSFIYGFVREHYRPNMALEDCVTFVKKAVQHAIYHDGSSGGVVRIGIITKDGIERRIFYN 206
            ..||||:|:.||:...:|||:.||:|...||:||..|.:.|||||||||:.:|.|.|.:..:|..
Worm   153 ASGSGSTFVQGFLDSQWRPNLTLEECKAIVKQAVGLATFRDGSSGGVVRLAVINKAGSQFELFRP 217

  Fly   207 TESGASAVSS-TP 218
            .:.|...|.: ||
Worm   218 DKPGFPFVQTPTP 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta1	NP_652031.2	20S_bact_beta	15..201	CDD:163402	96/185 (52%)
Prosbeta1	NP_652031.2	proteasome_beta_type_6	16..203	CDD:239731	95/186 (51%)
pbs-1	NP_500125.2	proteasome_beta_type_6	27..214	CDD:239731	95/186 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158263
Domainoid	1	1.000	213	1.000	Domainoid score	I1604
eggNOG	1	0.900	-	-		E1_KOG0174
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H137657
Inparanoid	1	1.050	220	1.000	Inparanoid score	I2291
Isobase	1	0.950	-	0	Normalized mean entropy	S496
OMA	1	1.010	-	-		QHG54145
OrthoDB	1	1.010	-	-		D1172133at2759
OrthoFinder	1	1.000	-	-		FOG0001868
OrthoInspector	1	1.000	-	-		oto20433
orthoMCL	1	0.900	-	-		OOG6_101390
Panther	1	1.100	-	-	LDO	PTHR11599
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1014
SonicParanoid	1	1.000	-	-		X1224
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	16	15.790