Protein Alignment Prosbeta1 and pbs-7

DIOPT Version :10

• Sequence 1: NP_652031.2
• Gene: Prosbeta1 / 46058
• FlyBaseID: FBgn0010590
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_492354.1
• Gene: pbs-7 / 172674
• WormBaseID: WBGene00003953
• Length: 236
• Species: Caenorhabditis elegans
• Alignment Length: 802
• Identity: 160/802 - (19%)
• Similarity: 261/802 - (32%)
• Gaps: 295/802 - (36%)

  Fly   750 GSIWQVLYIHHWIVAND-VWKLDLLSTVFNEYSDLCLSDAMTCQELLAFSVAFSAALPTGQTTLE 813
            |.::::|:.|:.|..:| :|. ::||.:|.....|.....:. ..|.:..:||   |.:|...:.
 Worm  1604 GYLFKILHRHNEISPDDGIWD-NMLSPLFISIKTLVKRFELK-HRLNSAPLAF---LLSGYKCIR 1663

  Fly   814 SFYTSLKRAKGAEPARQTNATLPLPEIERLSSKSSNEPSRTSFDPVSAGINNINMEEFACCYEYY 878
            ...|.....|..|..:.||..  |.|:.|.||:.          |.:.|.|      ||....::
 Worm  1664 QVPTDAYLPKALEIVKSTNDL--LLELTRASSQK----------PYTDGTN------FAADSGFH 1710

  Fly   879 QNQGLAEEKRPQRSKCARALLAVWRCFRRTCHLTRVLVK--KLVDHKYFQQGI--LLAI------ 933
                            .||:...  |......|||..:.  :|||.|  :.|:  ||.:
 Worm  1711 ----------------LRAIFGA--CLHMVGDLTRDCINGIQLVDSK--RSGLRKLLQLKLVFCL 1755

  Fly   934 --LINTLSMGIEYHDQPAE------------------LTAIVETSNIVFSAIFAVEMILKVIAEG 978
              |.:...:..|: |.|.:                  :.|:|:.||:...|  .|..:||.:.:
 Worm  1756 EQLFSLAKLAYEF-DCPVDETNTNSICIVMLKSCQISIAAVVKDSNVQVQA--TVLQVLKSLVQ- 1816

  Fly   979 PFRYVANGFNVFDGVIVILSVVELGQSYLGEGQGSSGLSVLRTFRLLRILKLVRFMPNLRRQLFV 1043
              ||    .|..:...|||.|.||    :|:                 |:.|      ::|.|..
 Worm  1817 --RY----NNPEEKSFVILFVGEL----IGD-----------------IVSL------MQRALLK 1848

  Fly  1044 MLRTMDNVAIFFSLLILFIFIFSILGMNLFGCKFCEKNETAGEVECDRKNFDSLLWALVTVFQIL 1108
            .:.| ::|.|....| .||.:.             :.:....|::   |.|.||...:|
 Worm  1849 PVNT-ESVVIAGECL-RFIMLL-------------QTHSITDELQ---KGFMSLFLEVV------ 1889

  Fly  1109 TQEDWNVVLFNGMEKTSHWAALYFVTLMTFGNYVLFNLLVAILVEGFSSERNERREREQRELVKA 1173
                  :|:|:   |||                           :|.|.|..|.|.      |..
 Worm  1890 ------LVVFS---KTS---------------------------DGVSQEVLELRN------VAV 1912

  Fly  1174 KLNAEALAQEQSMEVYDDQRSFSESSTTDSYNGSRGKWYSVEELTKVRNLDIKCNIQKQRLLQPN 1238
            :| ...|||..|..|:......|               ..|....::::: |:.::.|...|
 Worm  1913 RL-VSHLAQLPSSAVHFKDVLLS---------------LPVTHRQQLQDI-IRASVSKDSAL--- 1957

  Fly  1239 YEDPKNVAQKNKREKDVSKPEPTATKKLRGKKAESLKLYNIQVQDPPIITTTAATPQDSPSGTM- 1302
             ..||::..    ..|:..|.|.                   |..|..:|:||...::....||
 Worm  1958 -AKPKSLVP----AMDIKLPAPV-------------------VATPEKVTSTANMVKEEALSTMP 1998

  Fly  1303 ---------ESGTSFK----------DWD-------QADFEKYERENSSLL-KPPSILGSLKTLD 1340
                     ||||..:          |||       ..:.|..|.:..|:. :.|.:.|.....|
 Worm  1999 TSFNQVSTVESGTDEEEEEEEDDDDDDWDTFQSFPASTNLEGSESKTESVAEEEPDLPGRSSIQD 2063

  Fly  1341 DRSFFEGTPVLNEMRKKHDKNHTTSSDSRLSVVDKQQKKQQEKSLTESASAPKAVGKDETANGGL 1405
            |.|..|.|          |..|..|..:    .|..::...:||        |.|.::||.....
 Worm  2064 DESNAEET----------DDQHLASDHA----TDITREDSNDKS--------KEVVEEETVEPCF 2106

  Fly  1406 HRQASTEEGVLNNGKILSQPKGKNGFGATDRRTLDP-LLEKSNRIQND--TQGSRTPNRRRSSVR 1467
                :|.|..::..|            ..:..|:.| |:|.:...|||  :.|.........||
 Worm  2107 ----TTREDSVDKSK------------EVEEETVKPCLIEDALTSQNDKTSSGDHPVEINEQSV- 2154

  Fly  1468 RSSSVKVDSGASSIASNLSLTS 1489
              .|..::|  .:|.:::.|.|
 Worm  2155 --ESKNLES--ENIGTDIKLAS 2172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta1	NP_652031.2	proteasome_beta_type_6	16..203	CDD:239731
pbs-7	NP_492354.1	proteasome_beta_type_4	16..218	CDD:239729