DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phb2 and PHB2

DIOPT Version :9

Sequence 1:	NP_001097372.1	Gene:	Phb2 / 46038	FlyBaseID:	FBgn0010551	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_011747.2	Gene:	PHB2 / 853146	SGDID:	S000003463	Length:	310	Species:	Saccharomyces cerevisiae

Alignment Length:	287	Identity:	149/287 - (51%)
Similarity:	217/287 - (75%)	Gaps:	1/287 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SKLNDLAGKLGKGGPPGLGIGLKVLAAVGAAAYGVSQSLYTVEGGHRAIIFSRLGGIQSDIYSEG 68
            ||:....|:.....|.|...||..|..:|..|..::.:|:.|:||||||::||:.|:.|.|::||
Yeast    20 SKVQQTGGRGQVPSPRGAFAGLGGLLLLGGGALFINNALFNVDGGHRAIVYSRIHGVSSRIFNEG 84

  Fly    69 LHVRIPWFQYPIIYDIRSRPRKISSPTGSKDLQMINISLRVLSRPDSLNLPYLHKQLGVDYDEKV 133
            .|...||...|||||:|::||.::|.||:|||||:||:.|||||||.:.||.:::.||.||||:|
Yeast    85 THFIFPWLDTPIIYDVRAKPRNVASLTGTKDLQMVNITCRVLSRPDVVQLPTIYRTLGQDYDERV 149

  Fly   134 LPSICNEVLKSVIAKFNASQLITQRQQVSLLIRKELVERARDFNIILDDVSLTELSFGKEYTAAI 198
            ||||.|||||:|:|:||||||||||::||.|||:.||.||..|||:|||||:|.::|..|:|.|:
Yeast   150 LPSIVNEVLKAVVAQFNASQLITQREKVSRLIRENLVRRASKFNILLDDVSITYMTFSPEFTNAV 214

  Fly   199 EAKQVAQQEAQRAVFFVERAKQEKQQKIVQAEGEAEAAKMLGLAVKQNPAYLKLRKLRAAQSIAR 263
            ||||:|||:||||.|.|::|:||||..:|:|:|||::|:::|.|:|::..|::|::|..|:.||:
Yeast   215 EAKQIAQQDAQRAAFVVDKARQEKQGMVVRAQGEAKSAELIGEAIKKSRDYVELKRLDTARDIAK 279

  Fly   264 TIASSQNKVYLSADSLMLN-IQDSGFD 289
            .:|||.|:|.|..::|:|| :.|:..|
Yeast   280 ILASSPNRVILDNEALLLNTVVDARID 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phb2	NP_001097372.1	SPFH_prohibitin	42..236	CDD:259799	118/193 (61%)
PHB2	NP_011747.2	SPFH_prohibitin	58..252	CDD:259799	118/193 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	225	1.000	Domainoid score	I433
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5263
Inparanoid	1	1.050	301	1.000	Inparanoid score	I498
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63567
OrthoFinder	1	1.000	-	-		FOG0002111
OrthoInspector	1	1.000	-	-		oto100065
orthoMCL	1	0.900	-	-		OOG6_101763
Panther	1	1.100	-	-	LDO	PTHR23222
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2721
SonicParanoid	1	1.000	-	-		X1399
TreeFam	1	0.960	-	-
	14	13.860