DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Phb2 and PHB1

DIOPT Version :9

Sequence 1:	NP_001097372.1	Gene:	Phb2 / 46038	FlyBaseID:	FBgn0010551	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_194580.1	Gene:	PHB1 / 828969	AraportID:	AT4G28510	Length:	288	Species:	Arabidopsis thaliana

Alignment Length:	278	Identity:	155/278 - (55%)
Similarity:	212/278 - (76%)	Gaps:	2/278 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 KLGKGGPPGLGIGLKVLAAVGAAAYGVSQSLYTVEGGHRAIIFSRLGGIQSDIYSEGLHVRIPWF 76
            |:..||  .:...|||....|...||.:.|||.||||||||:|:||.||:..:|.||.|:.||||
plant     8 KIPGGG--AISTLLKVGIIGGLGLYGATHSLYNVEGGHRAIMFNRLVGIKDKVYPEGTHLMIPWF 70

  Fly    77 QYPIIYDIRSRPRKISSPTGSKDLQMINISLRVLSRPDSLNLPYLHKQLGVDYDEKVLPSICNEV 141
            :.|:|||:|:||..:.|.:||:||||:.|.||||:||.:..||.:::.||.:|.|:|||||.||.
plant    71 ERPVIYDVRARPYLVESTSGSRDLQMVKIGLRVLTRPMADQLPEIYRSLGENYSERVLPSIINET 135

  Fly   142 LKSVIAKFNASQLITQRQQVSLLIRKELVERARDFNIILDDVSLTELSFGKEYTAAIEAKQVAQQ 206
            ||:|:|::|||||||||:.||..|||.|.|||.:||:.|||||:|.|:||||:||||||||||.|
plant   136 LKAVVAQYNASQLITQREAVSREIRKILTERAANFNVALDDVSITNLTFGKEFTAAIEAKQVAAQ 200

  Fly   207 EAQRAVFFVERAKQEKQQKIVQAEGEAEAAKMLGLAVKQNPAYLKLRKLRAAQSIARTIASSQNK 271
            ||:||.|.||:|:|:|:..:::|:|||::|:::|.|:..|.|::.|||:.||:.||:|||:|.||
plant   201 EAERAKFIVEKAEQDKRSAVIRAQGEAKSAQLIGQAIANNQAFITLRKIEAAREIAQTIANSANK 265

  Fly   272 VYLSADSLMLNIQDSGFD 289
            ||||:|.|:||:|....|
plant   266 VYLSSDDLLLNLQGMNLD 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phb2	NP_001097372.1	SPFH_prohibitin	42..236	CDD:259799	117/193 (61%)
PHB1	NP_194580.1	SPFH_prohibitin	36..230	CDD:259799	117/193 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	224	1.000	Domainoid score	I690
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5263
Inparanoid	1	1.050	311	1.000	Inparanoid score	I737
OMA	1	1.010	-	-		QHG63567
OrthoDB	1	1.010	-	-		D1089994at2759
OrthoFinder	1	1.000	-	-		FOG0002111
OrthoInspector	1	1.000	-	-		otm2842
orthoMCL	1	0.900	-	-		OOG6_101763
Panther	1	1.100	-	-	LDO	PTHR23222
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1399
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840