DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phb2 and Stoml2

DIOPT Version :9

Sequence 1:	NP_001097372.1	Gene:	Phb2 / 46038	FlyBaseID:	FBgn0010551	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_075720.1	Gene:	Stoml2 / 66592	MGIID:	1913842	Length:	353	Species:	Mus musculus

Alignment Length:	298	Identity:	60/298 - (20%)
Similarity:	116/298 - (38%)	Gaps:	66/298 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 AIIFSRLGGIQSDIYSEGLHVRIPWFQYPIIYDIRSRPRKISSPTGSKDLQMINISLRVLSRPDS 115
            |.:..|:|.... |...||:|.||         :..|.|.:.|   .|:: :||:..:.....|:
Mouse    46 AWVVERMGRFHR-ILEPGLNVLIP---------VLDRIRYVQS---LKEI-VINVPEQSAVTLDN 96

  Fly   116 LNL------------PYLHKQLGVDYDEKVLPSICNEVLKSVIAKFNASQLITQRQQVSLLIRKE 168
            :.|            || ....||:..|..:..:....::|.:.|.:..::..:|:.::..| .:
Mouse    97 VTLQIDGVLYLRIMDPY-KASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNANI-VD 159

  Fly   169 LVERARD------FNIILDDVSLTELSFGKEYTAAIEAKQ-----VAQQEAQR--AVFFVERAKQ 220
            .:.:|.|      ....:.|:.:.. ...:.....:||::     |.:.|..|  |:...|..||
Mouse   160 AINQAADCWGIRCLRYEIKDIHVPP-RVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQ 223

  Fly   221 --------EKQQKIVQAEGE-----------AEAAKMLGLAVKQNPAYLKLRKLRAAQSIARTIA 266
                    ||.::|.||.||           |||.::|..|:.|:..     ...|:.::|....
Mouse   224 AQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRILAGALTQHNG-----DAAASLTVAEQYV 283

  Fly   267 SSQNKVYLSADSLMLNIQDSGFDDMTEKVYKIGTGLPK 304
            |:.:|:...:::::|....|....|..:...:...|.|
Mouse   284 SAFSKLAKDSNTVLLPSNPSDVTSMVAQAMGVYGALTK 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phb2	NP_001097372.1	SPFH_prohibitin	42..236	CDD:259799	47/228 (21%)
Stoml2	NP_075720.1	HflC	38..314	CDD:223407	58/289 (20%)
		SPFH_paraslipin	74..184	CDD:259811	19/115 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	324..353
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900