DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phb2 and phb2a

DIOPT Version :9

Sequence 1:	NP_001097372.1	Gene:	Phb2 / 46038	FlyBaseID:	FBgn0010551	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_955975.1	Gene:	phb2a / 324421	ZFINID:	ZDB-GENE-030131-3141	Length:	302	Species:	Danio rerio

Alignment Length:	289	Identity:	208/289 - (71%)
Similarity:	256/289 - (88%)	Gaps:	2/289 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KLNDLAGKLGKGGPPGLGIGLKVLAAVGAAAYGVSQSLYTVEGGHRAIIFSRLGGIQSD-IYSEG 68
            :|..:|.::| .||.|.|:|:|:|...||.||||.::.||||||.||:||||:||:|.| :.:||
Zfish    12 QLRQIASRMG-SGPRGAGLGVKLLIGAGALAYGVKEATYTVEGGQRAVIFSRIGGMQMDTVLAEG 75

  Fly    69 LHVRIPWFQYPIIYDIRSRPRKISSPTGSKDLQMINISLRVLSRPDSLNLPYLHKQLGVDYDEKV 133
            ||.|:||||||||||||:|||||||.||||||||:||.|||||||.:..||.:::|||.||||:|
Zfish    76 LHFRMPWFQYPIIYDIRARPRKISSLTGSKDLQMVNIGLRVLSRPVASQLPIMYQQLGKDYDERV 140

  Fly   134 LPSICNEVLKSVIAKFNASQLITQRQQVSLLIRKELVERARDFNIILDDVSLTELSFGKEYTAAI 198
            ||||.|||||||:||||||||||||.|||||||::|:|||:|||||||||::|||||.||||||:
Zfish   141 LPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRDLIERAKDFNIILDDVAITELSFSKEYTAAV 205

  Fly   199 EAKQVAQQEAQRAVFFVERAKQEKQQKIVQAEGEAEAAKMLGLAVKQNPAYLKLRKLRAAQSIAR 263
            |||||||||||||.||||:|||:::|||:|||||||||||||.||.:||.|||||::||||:||:
Zfish   206 EAKQVAQQEAQRAQFFVEKAKQDQRQKIIQAEGEAEAAKMLGQAVTKNPGYLKLRRIRAAQNIAK 270

  Fly   264 TIASSQNKVYLSADSLMLNIQDSGFDDMT 292
            |:|:||||||||||||:||:|||.|::::
Zfish   271 TVAASQNKVYLSADSLVLNLQDSSFNNLS 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phb2	NP_001097372.1	SPFH_prohibitin	42..236	CDD:259799	151/194 (78%)
phb2a	NP_955975.1	SPFH_prohibitin	49..243	CDD:259799	151/193 (78%)
phb2a	NP_955975.1	PHB	49..209	CDD:214581	123/159 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580327
Domainoid	1	1.000	283	1.000	Domainoid score	I1609
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5263
Inparanoid	1	1.050	417	1.000	Inparanoid score	I1790
OMA	1	1.010	-	-		QHG63567
OrthoDB	1	1.010	-	-		D1089994at2759
OrthoFinder	1	1.000	-	-		FOG0002111
OrthoInspector	1	1.000	-	-		otm26012
orthoMCL	1	0.900	-	-		OOG6_101763
Panther	1	1.100	-	-	LDO	PTHR23222
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1399
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.870