DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phb2 and sto-6

DIOPT Version :9

Sequence 1:	NP_001097372.1	Gene:	Phb2 / 46038	FlyBaseID:	FBgn0010551	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_509943.1	Gene:	sto-6 / 190619	WormBaseID:	WBGene00006068	Length:	298	Species:	Caenorhabditis elegans

Alignment Length:	222	Identity:	45/222 - (20%)
Similarity:	96/222 - (43%)	Gaps:	32/222 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 RAIIFSRLGGIQ-SDIYSEGLHVRIPWFQYPIIYDIRS-----RPRKISSPTGSKDLQMINISLR 108
            ||:|| |||.:: ......||...:|........|:|:     .|:::.    |||...:.:...
Worm    63 RAVIF-RLGRVKPGGARGPGLFFVVPCIDSYKKIDLRTLSFEVPPQELL----SKDAVTVAVDAV 122

  Fly   109 VLSRPDSLNLPYLHKQLGVDYDEKVLPSICNEVLKSVIAKFNASQLITQRQQVSLLIRKELVERA 173
            |..|..:..:..::    ::...:....:....|::::.....:::::.|..:||.::..|.|..
Worm   123 VFFRISNATISVIN----IEDAARSTKLLAQTTLRNILGTKTLTEMLSDRDVISLQMQATLDETT 183

  Fly   174 RDFNIILDDVSLTELSFGKEYTAAIEAKQVAQQEAQRAVFFVERAKQEKQQKIVQAEGEAEAAKM 238
            ..:.:.::.|.:      |:.....:.::|...||:        |.::...||:.||||..|:..
Worm   184 IPWGVKVERVEM------KDVRLPYQLQRVMAAEAE--------ATRDAMAKIIAAEGEKNASTA 234

  Fly   239 LGLA---VKQNPAYLKLRKLRAAQSIA 262
            |..|   :..:|..::||.|:...||:
Worm   235 LAEAADVISMSPCAIQLRYLQTLNSIS 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phb2	NP_001097372.1	SPFH_prohibitin	42..236	CDD:259799	36/191 (19%)
sto-6	NP_509943.1	PRK11029	37..>98	CDD:182913	11/35 (31%)
sto-6	NP_509943.1	SPFH_like	74..275	CDD:388510	38/210 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810