Protein Alignment Ccs and CCS

DIOPT Version :10

• Sequence 1: NP_001163108.1
• Gene: Ccs / 46035
• FlyBaseID: FBgn0010531
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_005116.1
• Gene: CCS / 9973
• HGNCID: 1613
• Length: 274
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 128/266 - (48%)
• Similarity: 178/266 - (66%)
• Gaps: 22/266 - (8%)

  Fly     6 IEFAVQMRRGDESYAGALRSALDGVG---QVEIDTQEGRVIIQTQRPWSEIQDKIEATGVRAVLS 67
            :||||||.  .:|...|:|.:|.||.   .||:..::..|::.|..|..|:|..:|.||.:|||.
Human    14 LEFAVQMT--CQSCVDAVRKSLQGVAGVQDVEVHLEDQMVLVHTTLPSQEVQALLEGTGRQAVLK 76

  Fly    68 GFG-GQ-----SAVALINTTGSVVDKTPIQGVVRFTTITADKKPGVVVDGVVDGLSPGLHGLHIH 126
            |.| ||     :|||::...|:|      ||||||..:|.::   .:::|.:|||.|||||||:|
Human    77 GMGSGQLQNLGAAVAILGGPGTV------QGVVRFLQLTPER---CLIEGTIDGLEPGLHGLHVH 132

  Fly   127 ESGDTSAGCSSVGEHYNPRQSPHGSPAAGAEERHAGDLGNIRADENGRATFRFVDPVLEVWDIIG 191
            :.||.:..|:|.|.|:||..:.||.|.  ..:||.|||||:|||.:|||.||..|..|:|||:||
Human   133 QYGDLTNNCNSCGNHFNPDGASHGGPQ--DSDRHRGDLGNVRADADGRAIFRMEDEQLKVWDVIG 195

  Fly   192 RAVVLTANADDLGRGGNDQSLIDGNSGERIACGIIARSAGILENFKRICACDGVTLWDERNKPLA 256
            |::::....|||||||:..|.|.||||||:||||||||||:.:|.|:||:|||:|:|:||.:|:|
Human   196 RSLIIDEGEDDLGRGGHPLSKITGNSGERLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIA 260

  Fly   257 GKERSQ 262
            ||.|.:
Human   261 GKGRKE 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ccs	NP_001163108.1	Sod_Cu	90..226	CDD:459663	71/135 (53%)
CCS	NP_005116.1	PLN02957	14..253	CDD:215516	120/251 (48%)
		Superoxide dismutase-like	88..234		80/156 (51%)