DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ccs and CCS

DIOPT Version :9

Sequence 1:	NP_001163108.1	Gene:	Ccs / 46035	FlyBaseID:	FBgn0010531	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_563910.2	Gene:	CCS / 837808	AraportID:	AT1G12520	Length:	320	Species:	Arabidopsis thaliana

Alignment Length:	255	Identity:	83/255 - (32%)
Similarity:	122/255 - (47%)	Gaps:	29/255 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSSIKIEFAVQMRRGDESYAGALRSAL---DGVGQVEIDTQEGRVIIQTQRPWSEIQDKIEATGV 62
            |..:..||.|.|.  .|....|:::.|   :|:.:||:|.....|.|....|...:...:|.||.
plant    84 MPQLLTEFMVDMT--CEGCVNAVKNKLETIEGIEKVEVDLSNQVVRILGSSPVKAMTQALEQTGR 146

  Fly    63 RAVLSGFGGQSAVALINTTGSVVDKTPIQGVVRFTTITADKKPGVVVDGVVDGLSPGLHGLHIHE 127
            :|.|.|.|..... |::...:......|.|||||..::.:.   ..::....|||||.|...|:|
plant   147 KARLIGQGVPQDF-LVSAAVAEFKGPDIFGVVRFAQVSMEL---ARIEANFTGLSPGTHSWCINE 207

  Fly   128 SGDTSAGCSSVGEHYNPRQSPHGSPAAGAEERHAGDLGNIRADENGRATFRFVDPVLEVWDIIGR 192
            .||.:.|.:|.|..|||.|...|:       ...||||.:.||:||.|.:......|:|.|:|||
plant   208 YGDLTNGAASTGSLYNPFQDQTGT-------EPLGDLGTLEADKNGEAFYSGKKEKLKVADLIGR 265

  Fly   193 AVVLTANADDLGRGGNDQSLIDGNSGERIACGIIARSAGILENFKRICACDGVTLWDERN 252
            |||:....|:             .||..:...:||||||:.||:|::|:|||..:|:..|
plant   266 AVVVYKTDDN-------------KSGPGLTAAVIARSAGVGENYKKLCSCDGTVIWEATN 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ccs	NP_001163108.1	PLN02957	1..253	CDD:215516	83/255 (33%)
		HMA	5..64	CDD:238219	17/61 (28%)
		Cu-Zn_Superoxide_Dismutase	72..223	CDD:238186	46/150 (31%)
CCS	NP_563910.2	PLN02957	82..320	CDD:215516	83/255 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	41	1.000	Domainoid score	I4831
eggNOG	1	0.900	-	-		E1_COG2608
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3762
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55645
OrthoDB	1	1.010	-	-		D1527306at2759
OrthoFinder	1	1.000	-	-		FOG0000641
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_105544
Panther	1	1.100	-	-	LDO	PTHR10003
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4274
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.790