Protein Alignment Ccs and SOD3

DIOPT Version :10

• Sequence 1: NP_001163108.1
• Gene: Ccs / 46035
• FlyBaseID: FBgn0010531
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_003093.2
• Gene: SOD3 / 6649
• HGNCID: 11181
• Length: 240
• Species: Homo sapiens
• Alignment Length: 219
• Identity: 60/219 - (27%)
• Similarity: 93/219 - (42%)
• Gaps: 41/219 - (18%)

  Fly    50 WSEIQDKIEATGVRAVLSGFGGQSAVALINTTGSVVDKTP-IQGVVRFTTITADKKPGV--VVDG 111
            |.|:..:.:..         |...|...:..:.::....| :.|||.|..:....|...  .::|
Human    46 WQEVMQRRDDD---------GALHAACQVQPSATLDAAQPRVTGVVLFRQLAPRAKLDAFFALEG 101

  Fly   112 VVDGLSPGLHGLHIHESGDTSAGCSSVGEHYNPRQSPHGSPAAGAEERHAGDLGNIRADENGRAT 176
            .....:.....:|:|:.||.|.||.|.|.||||...||        .:|.||.||....:.....
Human   102 FPTEPNSSSRAIHVHQFGDLSQGCESTGPHYNPLAVPH--------PQHPGDFGNFAVRDGSLWR 158

  Fly   177 FR--FVDPVLEVWDIIGRAVVLTANADDLGRGGNDQSLIDGNSGERIACGIIARSAGILENFKRI 239
            :|  ....:.....|:|||||:.|..||||||||..|:.:||:|.|:||.::.           :
Human   159 YRAGLAASLAGPHSIVGRAVVVHAGEDDLGRGGNQASVENGNAGRRLACCVVG-----------V 212

  Fly   240 CACDGVTLWDERNKPLAGKERSQK 263
            |   |..||:.:     .:|.|::
Human   213 C---GPGLWERQ-----AREHSER 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ccs	NP_001163108.1	Sod_Cu	90..226	CDD:459663	49/139 (35%)
SOD3	NP_003093.2	Sod_Cu	78..210	CDD:459663	49/139 (35%)