DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bka and Fcf1

DIOPT Version :9

Sequence 1:	NP_524867.2	Gene:	Bka / 46032	FlyBaseID:	FBgn0010520	Length:	200	Species:	Drosophila melanogaster
Sequence 2:	NP_082908.2	Gene:	Fcf1 / 73736	MGIID:	1920986	Length:	198	Species:	Mus musculus

Alignment Length:	199	Identity:	136/199 - (68%)
Similarity:	159/199 - (79%)	Gaps:	7/199 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKHKKTQKVKKQRNAQLKRIIKPTDARLKDQIRVKRKKAE--DPHQIKVHEATQQSSALFFQYN 63
            |||.|||:|.     |.:||::...|.|||::.|:|.||.|  ||..:|..|..|..|.||||||
Mouse     1 MGKQKKTRKY-----ATMKRMLSLRDERLKEKDRLKPKKKEKKDPSALKEREVPQHPSCLFFQYN 60

  Fly    64 TQLGPPYHIVLDTNFINFSIKNKLDIVQGMMDCLYAKCIPYISDCVRAELEKLGNKYKLALRIIS 128
            |||||||||::||||||||||.|||:||.|||||||||||.|:|||.||:||||.|:::||||..
Mouse    61 TQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCVMAEIEKLGQKFRVALRIAK 125

  Fly   129 DPRFERLPCLHKGTYADDCLVERVRQHKCYIVATNDKDLKNRIRKIPGVPIMYVAAHKYAIERMP 193
            ||||:||||.|||||||||||:||.|||||||||.|:|||.||||||||||||::.|:|.|||||
Mouse   126 DPRFDRLPCTHKGTYADDCLVQRVTQHKCYIVATVDRDLKRRIRKIPGVPIMYLSNHRYNIERMP 190

  Fly   194 EAYG 197
            :.||
Mouse   191 DDYG 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bka	NP_524867.2	PIN_Fcf1	58..192	CDD:189034	106/133 (80%)
Fcf1	NP_082908.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	22..47		11/24 (46%)
Fcf1	NP_082908.2	PIN_Fcf1	55..189	CDD:189034	106/133 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836617
Domainoid	1	1.000	167	1.000	Domainoid score	I3856
eggNOG	1	0.900	-	-		E1_COG1412
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5706
Inparanoid	1	1.050	279	1.000	Inparanoid score	I2902
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54043
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003797
OrthoInspector	1	1.000	-	-		oto92462
orthoMCL	1	0.900	-	-		OOG6_101337
Panther	1	1.100	-	-	LDO	PTHR12416
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R437
SonicParanoid	1	1.000	-	-		X2651
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.790