DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bka and FCF1

DIOPT Version :9

Sequence 1:	NP_524867.2	Gene:	Bka / 46032	FlyBaseID:	FBgn0010520	Length:	200	Species:	Drosophila melanogaster
Sequence 2:	NP_057046.1	Gene:	FCF1 / 51077	HGNCID:	20220	Length:	198	Species:	Homo sapiens

Alignment Length:	199	Identity:	138/199 - (69%)
Similarity:	159/199 - (79%)	Gaps:	7/199 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKHKKTQKVKKQRNAQLKRIIKPTDARLKDQIRVKRKKAE--DPHQIKVHEATQQSSALFFQYN 63
            |||.|||:|.     |.:||::...|.|||::.|:|.||.|  ||..:|..|..|..|.||||||
Human     1 MGKQKKTRKY-----ATMKRMLSLRDQRLKEKDRLKPKKKEKKDPSALKEREVPQHPSCLFFQYN 60

  Fly    64 TQLGPPYHIVLDTNFINFSIKNKLDIVQGMMDCLYAKCIPYISDCVRAELEKLGNKYKLALRIIS 128
            |||||||||::||||||||||.|||:||.|||||||||||.|:|||.||:||||.||::||||..
Human    61 TQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCVMAEIEKLGQKYRVALRIAK 125

  Fly   129 DPRFERLPCLHKGTYADDCLVERVRQHKCYIVATNDKDLKNRIRKIPGVPIMYVAAHKYAIERMP 193
            |||||||||.|||||||||||:||.|||||||||.|:|||.||||||||||||::.|:|.|||||
Human   126 DPRFERLPCTHKGTYADDCLVQRVTQHKCYIVATVDRDLKRRIRKIPGVPIMYISNHRYNIERMP 190

  Fly   194 EAYG 197
            :.||
Human   191 DDYG 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bka	NP_524867.2	PIN_Fcf1	58..192	CDD:189034	108/133 (81%)
FCF1	NP_057046.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	22..47		11/24 (46%)
FCF1	NP_057046.1	PIN_Fcf1-like	57..187	CDD:350212	104/129 (81%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146516
Domainoid	1	1.000	170	1.000	Domainoid score	I3787
eggNOG	1	0.900	-	-		E1_COG1412
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5706
Inparanoid	1	1.050	282	1.000	Inparanoid score	I2891
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54043
OrthoDB	1	1.010	-	-		D1338131at2759
OrthoFinder	1	1.000	-	-		FOG0003797
OrthoInspector	1	1.000	-	-		oto88896
orthoMCL	1	0.900	-	-		OOG6_101337
Panther	1	1.100	-	-	LDO	PTHR12416
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R437
SonicParanoid	1	1.000	-	-		X2651
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800