Protein Alignment kermit and Gipc2

DIOPT Version :10

• Sequence 1: NP_652028.1
• Gene: kermit / 46027
• FlyBaseID: FBgn0010504
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_058563.1
• Gene: Gipc2 / 54120
• MGIID: 1889209
• Length: 314
• Species: Mus musculus
• Alignment Length: 332
• Identity: 159/332 - (47%)
• Similarity: 217/332 - (65%)
• Gaps: 23/332 - (6%)

  Fly     1 MPLFTRKSPKQGPTSDGGSQF-GSRSSMNSGSSQGSHISNNNNNSIPEKTKP--PLVFHCQLAHG 62
            |||..|...|...:.:..... |.|||    .|||          :|....|  .||||.|||||
Mouse     1 MPLGLRGKKKAAKSKEAARLVEGERSS----GSQG----------VPGPPAPARKLVFHAQLAHG 51

  Fly    63 SPTGLIHDFSSVRELYQKIAECFDISEKDILFCTLNSHKVDMTRLLGGQIGLDDFIFAHRKGRPK 127
            |.||.:.||||:.|||.|||..|:|:..:|||||||:.|:||.:|||||:||:||||||.||..|
Mouse    52 SATGRVEDFSSISELYAKIAGVFEIAPSEILFCTLNTPKIDMGKLLGGQLGLEDFIFAHVKGTKK 116

  Fly   128 EIEIVKSQDALGLTITDNGAGYAFIKRIKEDSIIDRIEHISVGDHIEKLNGQNMVGKRHYEVARM 192
            |:.:.||:|:|||||||||.|||||||||:.|.||.::.|.||||||.:||:|:||.||:|||:.
Mouse   117 EVNVYKSEDSLGLTITDNGVGYAFIKRIKDGSTIDSVKTICVGDHIECINGENIVGWRHFEVAKK 181

  Fly   193 LKDIATGETFTLRLVEPVRSGFQGIGPRSQSRASGSAGGKNYGSGKETLRFKANGNAQIEPQFDE 257
            ||::...|.|||:|:|| :..|: |||||:   :|....:..|:.:.|||.::.|.|.:|....|
Mouse   182 LKELKKEELFTLQLIEP-KKAFE-IGPRSK---AGKTSTEKIGTSRGTLRLRSKGPATVEELPSE 241

  Fly   258 ATVAGIEAINNLLESFMGINDTELASQIWDLGDQKSNSMDFAEAIDNSDLESFGFTDDFIIELWG 322
            |....|..:::|||.:|||.|.:||:.:::.|..|||..:||.|:|.: |..|.|.|:|:.::||
Mouse   242 AKAKAIGKVDDLLELYMGIRDIDLATTMFEAGKDKSNPDEFAVALDET-LGDFAFPDEFLFDVWG 305

  Fly   323 AITDARR 329
            ||:|.::
Mouse   306 AISDMKQ 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kermit	NP_652028.1	PDZ_GIPC	123..211	CDD:467191	54/87 (62%)
		GH2_GIPC	263..324	CDD:409666	25/60 (42%)
Gipc2	NP_058563.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36		13/48 (27%)
		PDZ_GIPC2	110..202	CDD:467291	55/92 (60%)
		GH2_GIPC	243..307	CDD:409666	25/64 (39%)