Protein Alignment NAT1 and eif4g1a

DIOPT Version :9

• Sequence 1: NP_001033943.2
• Gene: NAT1 / 46020
• FlyBaseID: FBgn0010488
• Length: 1488
• Species: Drosophila melanogaster
• Sequence 2: XP_009296603.1
• Gene: eif4g1a / 572435
• ZFINID: ZDB-GENE-070112-702
• Length: 1640
• Species: Danio rerio
• Alignment Length: 1208
• Identity: 308/1208 - (25%)
• Similarity: 478/1208 - (39%)
• Gaps: 378/1208 - (31%)

  Fly   389 SPSHQRYNNTNSLERNGGGGSGAGASGGPRSYGRSDADRYGGTPSSRTPNLRNG----SASAQIS 449
            :||:......:|    ||||.|                     ||:|.|....|    |.:.:|.
Zfish   699 TPSYANLGRQSS----GGGGRG---------------------PSARRPQPGRGKDQISRNPKII 738

  Fly   450 GSTSNSSNISLNSGSASAAGGGTPHSQQQQERSQAGKASTPPPITGRWIPPSLRPQHGLTQSEKN 514
            .|.|...||.||    .|....|| |.::|.||:.                         :.|::
Zfish   739 TSVSLKDNIELN----QAENAWTP-SVKKQVRSRG-------------------------EEEED 773

  Fly   515 DA-------VFRRVRGILNKLTPEKFQELSDELLKLDLNSIAILKGVILLIFDKALDEPKYSSMY 572
            ||       :|||||.:||||||:.||:|..::.:|.:::...|||||.|||:||:.||.:|..|
Zfish   774 DAEAAKTQELFRRVRSVLNKLTPQMFQQLMKQVTELAIDTEERLKGVIDLIFEKAISEPNFSVAY 838

  Fly   573 AQLCKRL-SEEAPSFDKEPSNSSTFLRLLIAVCRDKFNNRLKRDENDNRPPPENEA--DEEERRH 634
            |.:|:.| ..:.|:.|| |..:..|.:||:..|:.:|......||...:...|.:|  :||||:.
Zfish   839 ANMCRCLMGLKVPTSDK-PGVTVNFRKLLLNRCQKEFEKDKDDDEIFEQKQKELDAATEEEERQR 902

  Fly   635 L----------AKQRMLGNVKFIGELNKLDMLSKNVLHQCIMELFDKKKKRTAGTQEMCEDMECL 689
            |          |::|.|||:||||||.||.||::.::|.||::|.....:         :.:|||
Zfish   903 LNDELQDAKDKARKRSLGNIKFIGELFKLKMLTEPIMHDCIVKLLKNHDE---------DSLECL 958

  Fly   690 AQLLKTCGKNLDSEQGKELMNQYFEKLERRSKSSEYPPRIRFMLKDVIELRQNNWVPRKLGTTEG 754
            .:||.|.||:||.|:.|..|:|||.::|:..|..:...||||||:||::||:||||||:  ..:|
Zfish   959 CRLLSTIGKDLDFEKAKPRMDQYFHQMEKIIKEKKTSSRIRFMLQDVLDLRKNNWVPRR--GDQG 1021

  Fly   755 PVPIKQIRSD------------DDSIIRTPFPNRNRDMRNNDRDSDSWMNRFHLNIQPGGYNDMF 807
            |..|.||..:            ...::.....::.|..|.....|....::    .|..|:|
Zfish  1022 PKTIDQIHKEAELEEHREQIKVQQQLLSKKDSSQGRGGRGGPHSSGGRGSQ----TQDEGWN--- 1079

  Fly   808 SGLSVTGASPIVSPFATSNRDRDRDN-RQYNNRGDRNRD---------------RDQGGSGGANY 856
                       :.|..|.:|..|... .:....||.|..               ...||:|..:.
Zfish  1080 -----------IVPITTKSRPIDTSRLSKITKPGDFNNQLLAPGGKGSWGSWGKGSSGGTGAKST 1133

  Fly   857 G------------NRYNKHNQNGGGSGGGSSNNRDRDDSRRNN---DR-DRDRNDGQYGGNQLLG 905
            |            ||::...|:|..|...||.:.||...:||:   || ||||           |
Zfish  1134 GEQDQGRPTTSTLNRFSALQQSGPPSSSSSSMDSDRRVPQRNSSSRDRSDRDR-----------G 1187

  Fly   906 SKELAPRFKRNLITTNQDAVENLQMRP--AANSLLFRAASQNQKFPATLPMSTPPNSSGSNNQGS 968
            .::...||.|     ..|....|. ||  |.....|...|:.::              |.:|:
Zfish  1188 DRDRFDRFDR-----RDDRDRGLD-RPLQAITKRSFSRESEERR--------------GGDNR-- 1230

  Fly   969 SQGQLSNSHYPMLGTPTSHLINPTRPSSTPSAEYADNRTLLGVQQERGLKATSSSPNFSSGAEKL 1033
                         |.|.|    ..|.||     ..|||.
Zfish  1231 -------------GPPDS----VRRVSS-----MTDNRD-------------------------- 1247

  Fly  1034 DLDGQAGRKGSHDGKDQGKNGSVERPSTPA----GGIGSAKQQKKDKGPNKEELSKKASQYFKDR 1094
                    :||.| :|:.|. :|:..:.||    ..:..|.        ::|:|.||:....::.
Zfish  1248 --------RGSRD-RDRSKE-TVKPMAAPALPPPAPVKPAM--------SEEDLDKKSKSIIEEY 1294

  Fly  1095 FYYDEEEDAEVTEIEIKDID----------ETKTEEADAAPVEVSEVKEDAAIPVTTPDRFTKLV 1149
            .:.::.::|.....|:..:.          |...|.:..|...:..:             |.|||
Zfish  1295 LHINDLKEAVQCVQELNSVSLLFVFVRNGVEATLERSTIAREHIGLL-------------FQKLV 1346

  Fly  1150 DGFLELKLPEKALKDVCINLLMEVLDRVNDVFLERAVRLLQTLRKQSNIKPNIVVEIFKQVVNKM 1214
            ..  ::..||:..|.     |.|:|:..:|:.::               .|:|.:.:.:.:...:
Zfish  1347 SA--KILHPEQYYKG-----LQEILEIADDMAID---------------IPHIWLYLAEIITPML 1389

  Fly  1215 NE---------REALNPRIVSLVASLLAKTICEPALLKLSDIANFTDNGQHYPLFLLVLQQLVKV 1270
            .:         ||...|.:....|::|           |.|:.|....|..:           |.
Zfish  1390 QDGGIPMGQLFREVSKPLLPMGKAAIL-----------LVDVLNIFCKGLSH-----------KK 1432

  Fly  1271 IGKDALEEKFRASKVDLMNSLPE-ADRNKERLAGILEDRKLSFLY------PLLK-VQAEMLKQ- 1326
            .|...||     :.:...:.||| .|.||     .:.::|:.|..      |..| :.||.|.:
Zfish  1433 AGAMWLE-----AGLSWKDFLPEDEDVNK-----FVTEQKMEFTLGEESEKPSKKELTAEELSKH 1487

  Fly  1327 ----LQSDPNPNNFYKWIKANVDNKYYKDPGFIQALMTVVVKYVTKETTLADNLDPKEHPEKSVT 1387
                ||...|....|.|::||:|.:......|::|||    ..|.:...:.:|  |.....:.:.
Zfish  1488 LDRLLQEKANNQRIYDWVEANLDEQKMSSSQFVRALM----MSVCQSAIICEN--PYRVDVEQIN 1546

  Fly  1388 QKEQQLLENYSQMLQTFLGQNELQLMALYALQTFCYNENFPKGMLCRWFKYLYESEIIEEEAFVL 1452
            |:        :::||.:|...:.:|.||||||........|..:|..:|..||:.::|:||||..
Zfish  1547 QR--------AKLLQKYLSDEQKELQALYALQALMVQMEQPANLLRMFFDALYDEDVIKEEAFYK 1603

  Fly  1453 WKEEISDKYP----GKGSALFQVNAWLTWLQEAESEDD 1486
            |:   |.|.|    |||.||..|.|:.|||:|||||.|
Zfish  1604 WE---SSKDPAEQQGKGVALKSVTAFFTWLREAESESD 1638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NAT1	NP_001033943.2	MIF4G	518..743	CDD:280935	97/237 (41%)
		RAM	<817..865	CDD:291966	13/75 (17%)
		MA3	1128..1241	CDD:214714	18/121 (15%)
		W2_eIF4G1_like	1314..1460	CDD:211397	43/157 (27%)
eif4g1a	XP_009296603.1	MIF4G	784..1012	CDD:280935	97/237 (41%)
		MA3	1285..1395	CDD:280933	20/144 (14%)
		W2_eIF4G1_like	1482..1611	CDD:211397	41/145 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D594395at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23253
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.020