Protein Alignment NAT1 and tif471

DIOPT Version :9

• Sequence 1: NP_001033943.2
• Gene: NAT1 / 46020
• FlyBaseID: FBgn0010488
• Length: 1488
• Species: Drosophila melanogaster
• Sequence 2: NP_594602.1
• Gene: tif471 / 2542290
• PomBaseID: SPAC17C9.03
• Length: 1403
• Species: Schizosaccharomyces pombe
• Alignment Length: 641
• Identity: 168/641 - (26%)
• Similarity: 259/641 - (40%)
• Gaps: 162/641 - (25%)

  Fly   324 SNGTQPRYGSGNGNGNSSNSNSSSGYNGSAASSTNSKSSYGASRGGNDGGVSS---GYSSNYRDN 385
            |.|........:.:|::::|::..|:.|.:...       |.||.|.|.|.||   |:.|.  .|
pombe   867 SRGMYSSSRQSSRSGSNTHSHAGPGFGGPSERK-------GISRLGIDRGFSSSGAGFGSG--SN 922

  Fly   386 YEDSPSHQRYNNTNSLERNGGGGSGAGASGGPRSYGRSDADRYGGTPSSRTPNLRNGSASAQISG 450
            |:.:||       ..:..:|.||......|..|...|...:|....|||.|..: :..|..|:|.
pombe   923 YKSAPS-------RGVSHHGHGGMSGSHRGSQRGSRRGGGERDKPDPSSLTIPV-DQVAPLQLSA 979

  Fly   451 STSNSSNISLNSGSASAAGGGTPHSQQQQERSQAGKASTPPPITGRWIPPSLRPQHGLTQSEKND 515
            :                                            ||.|..|..:...|:.|..:
pombe   980 N--------------------------------------------RWQPKKLTEKPAETKGEDEE 1000

  Fly   516 A------VFRRVRGILNKLTPEKFQELSDELLKLDL-----NSIAILKGVILLIFDKALDEPKYS 569
            |      |.|:|:|.|||:|.|||.::||::|::.:     |....||.||.|.|:||.|||.:|
pombe  1001 ALLPPEVVQRKVKGSLNKMTLEKFDKISDQILEIAMQSRKENDGRTLKQVIQLTFEKATDEPNFS 1065

  Fly   570 SMYAQLCKRLSEEAPS-------FDK--EPSNSS-TFLRLLIAVCRDKFNNRLKRDENDNRPPPE 624
            :|||:..:::.:....       .||  :|.... .|.:.|::.|::.|....|.:      .|.
pombe  1066 NMYARFARKMMDSIDDSIRDEGVLDKNNQPVRGGLLFRKYLLSRCQEDFERGWKAN------LPS 1124

  Fly   625 NEADEEE----RRHLA---KQRMLGNVKFIGELNKLDMLSKNVLHQCIMELFDKKKKRTAG--TQ 680
            .:|.|.|    ..::|   |:|.||.|:|||||.||.|||:.::|:||        ||..|  |.
pombe  1125 GKAGEAEIMSDEYYVAAAIKRRGLGLVRFIGELFKLSMLSEKIMHECI--------KRLLGNVTD 1181

  Fly   681 EMCEDMECLAQLLKTCGKNLD-SEQGKELMNQYFEKLERRSKSSEYPPRIRFMLKDVIELRQNNW 744
            ...|::|.|.:||.|.|.|:| :|:|...|:.|..::|..:|....|.||:|||.||::.|:|.|
pombe  1182 PEEEEIESLCRLLMTVGVNIDATEKGHAAMDVYVLRMETITKIPNLPSRIKFMLMDVMDSRKNGW 1246

  Fly   745 VPRKLGTTEGPVPIKQIRSDDDSIIRTPFPNRNRDMRNNDRDSDSWMNRFHLNIQPGGYNDMFSG 809
            .. |....:||..|.:|..:.:         |.:.:..:.|.|...|:.          .||..|
pombe  1247 AV-KNEVEKGPKTIAEIHEEAE---------RKKALAESQRPSSGRMHG----------RDMNRG 1291

  Fly   810 LSVTGASPIVSPFATSNRDRDRDNRQYNNRGDRN-RDRDQGGSGGANYGNRYNKHNQNGGGSGGG 873
            .|..|......||::|:...::|......:|.|. :...||..|..:..:..         .||.
pombe  1292 DSRMGGRGSNPPFSSSDWSNNKDGYARLGQGIRGLKSGTQGSHGPTSLSSML---------KGGS 1347

  Fly   874 SSNNRDRDDS--RRN---------------------NDRDRDRNDGQYGGNQLLGS 906
            .|....|.:|  ||.                     .:.|.|.:.||...|....|
pombe  1348 VSRTPSRQNSALRREQSVRAPPSNVAVTSANSFELLEEHDHDNDGGQKDSNSKTSS 1403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NAT1	NP_001033943.2	MIF4G	518..743	CDD:280935	88/249 (35%)
		RAM	<817..865	CDD:291966	9/48 (19%)
		MA3	1128..1241	CDD:214714
		W2_eIF4G1_like	1314..1460	CDD:211397
tif471	NP_594602.1	ASFV_J13L	<213..>284	CDD:114299
		tolA_full	470..>574	CDD:274303
		FKBP_N	<515..564	CDD:279662
		eIF_4G1	784..846	CDD:288966
		MIF4G	1009..1244	CDD:280935	88/248 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	124	1.000	Domainoid score	I1416
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004422
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR23253
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010