Protein Alignment NAT1 and ifg-1

DIOPT Version :10

• Sequence 1: NP_001033943.2
• Gene: NAT1 / 46020
• FlyBaseID: FBgn0010488
• Length: 1488
• Species: Drosophila melanogaster
• Sequence 2: NP_001368728.1
• Gene: ifg-1 / 174322
• WormBaseID: WBGene00002066
• Length: 1160
• Species: Caenorhabditis elegans
• Alignment Length: 902
• Identity: 184/902 - (20%)
• Similarity: 331/902 - (36%)
• Gaps: 296/902 - (32%)

  Fly   436 TPNLRNGSASAQ---ISGSTSNSSNISLNSGSASAAGGGTPHSQQQQERSQAGKASTPPPITGRW 497
            |||..|...:.|   ..|.|:.         ..:..||     |||::|..    :..||:
 Worm   438 TPNWANKGGNRQQVPYRGRTTT---------DGTGRGG-----QQQRDRMH----NKRPPV---- 480

  Fly   498 IPPSLRPQHGLTQSEKNDA---------------------VFRRVRGILNKLTPEKFQELSDELL 541
            :.||:.....:|.....||                     |.::||.::||:||...:.|::|.:
 Worm   481 VRPSIERVQRVTLPSSKDAWKPDRQKTAEAVASEEAAVIEVCKKVRSLMNKVTPTSQRPLTEEFI 545

  Fly   542 KLDLNS-IAILKGVILLIFDKALDEPKYSSMYAQLCKRLSEEAPSFDKEPSNSSTFLRLLIAVCR 605
            ..:::| .|.|..|:.::||||::|||:.::||::||..:....|   :....|.|...::...:
 Worm   546 SYNVSSNDAQLAQVVEIVFDKAVEEPKFCALYAEMCKAQANHELS---QTGGKSAFRNKVLTRTQ 607

  Fly   606 DKFNNR----------LKRDENDNRPPPENEADEEERRHLAKQRMLGNVKFIGELNKLDMLSKNV 660
            ..|.::          ::::|:    |.:.|....|.:...::|..|.:.|:|.|.:..:||..:
 Worm   608 MTFQDKKDIDADKLAIIEKEED----PVKKELMLAEEKQKFRRRKFGVMTFMGYLYRNQLLSTKI 668

  Fly   661 LHQCIMELFDKKKKRTAGTQEMCED-MECLAQLLKTCGKNLDSEQGKE--LMNQYFEKLERRSKS 722
            :..|..|||:..|.:....:::.|: :.|..||::|.|..||..:...  .::|:|:|||   .:
 Worm   669 VQTCTFELFNSIKDQDIKKEDVDEESIHCGLQLIETVGVMLDKSKDSTTVFLDQWFQKLE---AA 730

  Fly   723 SEY-PPRIRFMLKDVIELRQNNWVPRKLGTTEGPVPIKQIRSDDDSIIRTPFPNRNRDMRNNDRD 786
            ..| ..:||||:.:::|||::.|:||| .|..||..|.:|..|    ||       ::...|::.
 Worm   731 KPYCSNKIRFMIMNLMELRKDKWIPRK-STESGPKKIDEIHKD----IR-------QEKIENEKA 783

  Fly   787 SDSWMNRFHLNIQPGGYNDMFSGLSVTGASPIVSPFATSNRDRDRDNRQYNNRGDRNRDRDQGGS 851
            .|.:                                     |||||.|
 Worm   784 RDQY-------------------------------------DRDRDRR----------------- 794

  Fly   852 GGANYGNRYNKHNQNGGGSGGGSSNNRDRDDSRRNNDRDRDRNDGQYGGNQLLGSKELAPRFKRN 916
                          :||.....:|..:....||.:.||:|        |.|       .|..||
 Worm   795 --------------HGGVRPNSNSLRKSVPVSRNSLDRNR--------GMQ-------HPEQKR- 829

  Fly   917 LITTNQDAVENLQMRPAANSLLFRAASQNQKFPATLPMSTPPNSSGSNNQGSSQGQLSNSHYPML 981
                         ...|||:.|..::.|            |.|.|.|:
 Worm   830 -------------AAAAANTKLASSSVQ------------PKNISLSS----------------- 852

  Fly   982 GTPTSHLINPTRPSSTPSAEYADNRTLLGVQQERGLKATSSSPNFSSGAEKLDLDGQAGRKGSHD 1046
                                 .||.| ||..::......|...|.|| ...:.:....||:   |
 Worm   853 ---------------------MDNNT-LGKSKKEWHSGASGGGNTSS-ESAVPVKSAWGRR---D 891

  Fly  1047 GKDQGKNGSVERPSTPAGGIGSAKQQKKDKGPNKEELSKKASQYFKDRFYYDEEEDAEVTE---- 1107
            ..||.|..:|:...   ..:.:||:.......::...|:.::         .::.|.|:||
 Worm   892 SNDQRKKSTVDEKQ---AALAAAKEISAMSISSRRSTSQNSN---------TDKTDDELTEEEKA 944

  Fly  1108 IEIKDIDETKTEEADAAPVEVSEV-----------KEDAAIPVTTPDRFTKLVDGFLELKLPEKA 1161
            :..|.::..|::..:.:..|:|:.           ||....|..|. .:..::...:|..|.:..
 Worm   945 VRAKIMNTVKSDLLEMSSGELSQKELVDSITDYVGKEKYGSPSLTV-VYEMIIRAVIEKGLKDDD 1008

  Fly  1162 LKDVCINLLMEVLDRV-NDVFLERAVRLLQTLRKQSNIKPNIVVEIFKQVVNKMNEREALNPRIV 1225
            .|.:.|.|.|.::.:. ...|:|.|.|                   |.:..|.: |.:...|::.
 Worm  1009 RKKLAIALRMSLVSKTEKQAFIEGATR-------------------FCKFANDV-ELQQDYPKLW 1053

  Fly  1226 SLVASLLAKT-------ICEPALLKLSDI-----ANFTDNGQHYPLFLLVLQQLVKV 1270
            ::...:|..|       |.|.....|:|:     |...:..:.:.|.:.||:||:::
 Worm  1054 TVTGEVLVNTSHAPHDEIGEVESFSLADMKPIFSAAKGEGNKKFDLLVQVLKQLIEL 1110

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NAT1	NP_001033943.2	MIF4G	518..743	CDD:397130	64/239 (27%)
		RAM	<817..860	CDD:464643	6/42 (14%)
		MA3	1128..1241	CDD:214714	23/131 (18%)
		W2_eIF4G1_like	1314..1460	CDD:211397
ifg-1	NP_001368728.1	Atrophin-1	<226..>334	CDD:460830
		MIF4G	522..752	CDD:397130	64/239 (27%)