Protein Alignment l(2)01289 and p4hb

DIOPT Version :9

• Sequence 1: NP_001163065.1
• Gene: l(2)01289 / 46017
• FlyBaseID: FBgn0010482
• Length: 1786
• Species: Drosophila melanogaster
• Sequence 2: NP_001034820.1
• Gene: p4hb / 395048
• XenbaseID: XB-GENE-494070
• Length: 506
• Species: Xenopus tropicalis
• Alignment Length: 625
• Identity: 133/625 - (21%)
• Similarity: 230/625 - (36%)
• Gaps: 188/625 - (30%)

  Fly   663 ALIYFENKIPALYEGDLMNEDEVLEWLLVQKKTATIEEVTDEILVTLINEHEYVVVFFTGPCEPG 727
            |::.|...:..:...::..|.:|    ||.||     :..||.|    .::.:::|.|..|
 Frog     4 AVLLFGCSLLIVARANIPEERDV----LVLKK-----DNFDEAL----KQYPFILVEFYAP---- 51

  Fly   728 ETCEHTLNALESIDDELDEAGIIFVT------------TEDTGIAKKYNVKTYPRLVFFRNRD-- 778
             .|.|    .:::..|.::|..:..:            ||::.:|:::.|:.||.:.||:|.|
 Frog    52 -WCGH----CKALAPEYEKAAGVLKSEGLPIRLGKVDATEESDLAQEFGVRGYPTIKFFKNGDKA 111

  Fly   779 -PLHFTGDLDDEDEVLAWITDDETLEIPGKIEEVNVKMLDKILAENDHVVV--FFYAEGDKKAQK 840
             |..::...:..| ::.|:............:|..|    ..|.::..|.|  ||.....:.|:.
 Frog   112 SPKEYSAGREAAD-IVNWLKKRTGPAASTLGDEAGV----AALVDSSEVAVIGFFKDPASEPAKV 171

  Fly   841 ILNELENIDDECEEKDIDFVKTSDDDIDKEYDLPGLPALAFYRHKF---RTIYTGDLMKEEEI-- 900
            .|...|.:|      ||.|..||.:....:|:| |...:..:: ||   |..|.||:.|||.:
 Frog   172 FLQAAEAVD------DIPFGITSSEAAFSKYEL-GKDGIVLFK-KFDEGRNAYEGDITKEEVLSF 228

  Fly   901 -----LEWVIDLHESTADVIESVDRKTLQVLINDVEHLAVFFYDDECESCSDILEELENIDDDTD 960
                 |..||:..|.||.:|...:.||         |: :||..   :|.||..|:||
 Frog   229 IKANRLPLVIEFTEQTAPMIFGGEIKT---------HI-LFFLP---KSASDYKEKLE------- 273

  Fly   961 KHGIQFVKSNDVKLAHEIGIFAFPALVYYETGVPIMYDGNIASNQDVFNWI-LEQKADQSIQLIN 1024
                      |.|.|    ..:|...:.:     |..|.:...||.:..:. |:::...:::||.
 Frog   274 ----------DFKKA----AASFKGKILF-----IFIDSDHTDNQRILEFFGLKKEECPAVRLIT 319

  Fly  1025 RDQLFEYIGTKDFLAVVFYKEDDPDSPRVLRHIELIDDEAAEYGIYIVKMHDKLMAKKYGFRNPP 1089
            .::..    ||       ||.:..|     ...|.|.:....:....||.|  ||::
 Frog   320 LEEEM----TK-------YKPESAD-----LSAEAIKEFCDSFLEGKVKPH--LMSQ-------- 358

  Fly  1090 GLTYFRKGKYINYDGDIDDEEEVLDWLTSPANMEMTDHIEQVNRKMFEKIRKNSDYVAVIFYSDE 1154
                           |:.|     ||..:|..:.:..:.|:|   :|.: .||   |.|.||:..
 Frog   359 ---------------DVSD-----DWDKNPVKILVGKNFEEV---VFNE-EKN---VFVEFYAPW 396

  Fly  1155 CKQCPRVLAEVEHIDDE-ADKAGIDFVKIDDKQMAKE-YGVFALPAIVFFKPTSKEPVIYAGDLY 1217
            |..|.::....:.:.:: .|...|...|:|......| ..:.:.|.:.||.         ||
 Frog   397 CGHCKQLAPIWDQLGEKYKDHENIIIAKMDSTANEIEAVKIHSFPTLKFFP---------AG--- 449

  Fly  1218 EEEQILTWLITQKDPSGDVIEDLEGERLVH----LIEESG 1253
                           .|..:.|..|||.:.    .:|..|
 Frog   450 ---------------PGKNVADYNGERTLEGFSKFLESGG 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)01289	NP_001163065.1	PDI_a_family	50..145	CDD:239259
		PDI_a_family	384..479	CDD:239259
		Thioredoxin_6	510..689	CDD:404691	4/25 (16%)
		ER_PDI_fam	700..>916	CDD:273457	57/242 (24%)
		PDI_a_family	1129..1226	CDD:239259	21/98 (21%)
		TRX_family	1433..>1502	CDD:239245
p4hb	NP_001034820.1	ER_PDI_fam	25..474	CDD:273457	129/602 (21%)
		pdi_dom	29..133	CDD:273454	25/122 (20%)
		PDI_b_family	137..232	CDD:239279	28/106 (26%)
		PDI_b'_family	244..347	CDD:239280	32/157 (20%)
		PDI_a_PDI_a'_C	368..470	CDD:239293	27/135 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910