Protein Alignment hlk and LOC1273599

DIOPT Version :10

• Sequence 1: NP_001163065.1
• Gene: hlk / 46017
• FlyBaseID: FBgn0010482
• Length: 1786
• Species: Drosophila melanogaster
• Sequence 2: XP_312592.5
• Gene: LOC1273599 / 1273599
• VectorBaseID: AGAMI1_011399
• Length: 319
• Species: Anopheles gambiae
• Alignment Length: 304
• Identity: 73/304 - (24%)
• Similarity: 128/304 - (42%)
• Gaps: 68/304 - (22%)

  Fly  1433 LETMVEET--------QYLAVYFYKINCNICDQILEGLELIDDEC-DVFGIHMVKIQDPQLAKRY 1488
            |||:.|:.        ....|.|.|.||..||:....|..:..|. |....|.||.....:|:.|
Mosquito    22 LETVSEDDLVKKFHSHNNFIVLFSKPNCADCDKFEAILSKLKQEIEDNLQAHAVKAVSSSMARLY 86

  Fly  1489 SIKTFPALVYFRNGNPLLFEGDLQNEQSVLEWLI---DDDNRELADEIEEVNERMLDRLMAESTL 1550
            |....||:||||:|.|||::|.:: |.:::..||   |.:.:||:||..|    .|.:..:.:|.
Mosquito    87 SPSKEPAVVYFRHGVPLLYDGAIE-EDALIGKLIQNKDPNVKELSDETFE----HLTQASSGATT 146

  Fly  1551 --LVVFFYDDDCAECEEILEELEEIDGEADMFGIDFVKIASIQ-------AAKKYEIVNIPSLVY 1606
              ..:.||..:|.:|:.:....|.:  .||:  ...:.:|.:|       .|.::::..:|..|:
Mosquito   147 GDWFIMFYTTNCVDCQRLTAVWEAV--AADL--KTRMNVARVQKDGKGSETAARFQVKKVPDFVF 207

  Fly  1607 FRKQVPVLYDGDLHQHDKVITWLTSQDVFE-IKNEIEEVNRKMLDKLLEENEFLAVFFYEHNQPD 1670
            .|:.....|:...:.....:::  :||.:: .|.|...|.....|.|:|
Mosquito   208 LRQGKYYRYEISKYDIKSFVSF--AQDWYKNAKAERVPVPLSPFDNLVE---------------- 254

  Fly  1671 STAALEKLENIDSETDNLDITFVKMADSRYAKKWGVTKLPAMVY 1714
                             |.:.::|.|.:.|||.:  ::.|.:||
Mosquito   255 -----------------LAVQYLKDAPNMYAKLY--SEYPMVVY 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hlk	NP_001163065.1	PDI_a_family	50..145	CDD:239259
		ER_PDI_fam	381..>670	CDD:273457
		PDI_a_family	384..479	CDD:239259
		ER_PDI_fam	700..>916	CDD:273457
		PDI_a_family	1129..1226	CDD:239259
		TRX_family	1433..>1502	CDD:239245	26/77 (34%)
LOC1273599	XP_312592.5	None