DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment tutl and opcml

DIOPT Version :9

Sequence 1:NP_001303307.1 Gene:tutl / 46015 FlyBaseID:FBgn0010473 Length:1536 Species:Drosophila melanogaster
Sequence 2:NP_001005580.1 Gene:opcml / 449538 ZFINID:ZDB-GENE-040927-3 Length:342 Species:Danio rerio


Alignment Length:409 Identity:86/409 - (21%)
Similarity:125/409 - (30%) Gaps:159/409 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly   137 HITAILGEGVIFNCHVEFPNDHPVPYVLQWDKKVSE-----------TGSDLPIYIWYESYPEHI 190
            :||...|:..:..|.:              |.|||.           ||::.    |        
Zfish    41 NITVRQGDSAVLKCSM--------------DNKVSRVAWLNRTTILFTGNEK----W-------- 79

  Fly   191 EEGYKGRVSRVSQDSPFGSASLNLTNIRESDQGWYECKVVFLNRDPKQHKNGTWFHLDVHAPPRF 255
              ....||  |..::.....|:.:.|:...|:|.|.|.:: .|:.|:..|    .||.|..|.|.
Zfish    80 --SLDPRV--VLLNTAVNEYSIKILNVNLYDEGPYVCSIL-TNKKPESTK----VHLIVQVPARI 135

  Fly   256 SVTPEDIIYVNLGDSIILNCQADGTPTPEILWYKDANPVDPSPTVGIFNDGTELRISTIRHEDIG 320
            .....| :.||.|.::.|.|.|.|.|.|.|||.                                
Zfish   136 VNVSTD-VSVNEGSNVSLMCLAIGRPEPSILWK-------------------------------- 167

  Fly   321 EYTCIARNGEGQVSHTARVIIAGGAVIMVPPTNQTKLEGEKVIFSCEAKAMPGNVTVRWYREGSP 385
                 .|:.:|                     |:...|||.|       .|.|            
Zfish   168 -----FRSSKG---------------------NRIVTEGEYV-------EMTG------------ 187

  Fly   386 VREVAALETRVTIRKDGSLIINPIKPDDSGQYLCEVTNGIGDPQSASAYLSVEYP-----AKVTF 445
                                   |..|.||.|.|..:|.|..|...:..::|.||     |:.|.
Zfish   188 -----------------------ITKDMSGSYDCITSNDISPPDVRTVQVTVNYPPVISRARSTG 229

  Fly   446 TPTVQYLPFRLAGVVQCYIKSSPQLQYVTWTKDKRLLEPYQMKDIVVMANGSLL-FTRVNEEHQG 509
            |...|      .||:.|...:.|...:..:..::|:|..:....|......|:| |..|:||..|
Zfish   230 TAVGQ------KGVLWCEASAVPLADFQWFKGERRILNGFNGVKIENKGKQSMLTFFNVSEEDYG 288

  Fly   510 QYACTPYNAQGTAGASGVM 528
            .|.|...|..|...||.::
Zfish   289 NYTCVAINTLGITNASIIL 307

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tutlNP_001303307.1 V-set 137..250 CDD:284989 25/123 (20%)
IG_like 137..229 CDD:214653 20/102 (20%)
I-set 253..341 CDD:254352 16/87 (18%)
IGc2 268..331 CDD:197706 11/62 (18%)
I-set 346..437 CDD:254352 16/90 (18%)
Ig 349..437 CDD:299845 16/87 (18%)
Ig 459..530 CDD:299845 19/71 (27%)
IG_like 549..628 CDD:214653
IGc2 551..617 CDD:197706
FN3 633..725 CDD:238020
FN3 786..874 CDD:238020
opcmlNP_001005580.1 Ig 41..129 CDD:299845 25/122 (20%)
IG_like 41..129 CDD:214653 25/122 (20%)
IG_like 139..216 CDD:214653 31/177 (18%)
IGc2 146..202 CDD:197706 25/155 (16%)
I-set 219..307 CDD:254352 25/93 (27%)
ig 223..307 CDD:278476 24/89 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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