DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tutl and dpr5

DIOPT Version :9

Sequence 1:	NP_001303307.1	Gene:	tutl / 46015	FlyBaseID:	FBgn0010473	Length:	1536	Species:	Drosophila melanogaster
Sequence 2:	NP_650080.3	Gene:	dpr5 / 41381	FlyBaseID:	FBgn0037908	Length:	336	Species:	Drosophila melanogaster

Alignment Length:	285	Identity:	62/285 - (21%)
Similarity:	104/285 - (36%)	Gaps:	74/285 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 LLAKNAQAHNIPE--DAV----------HITAILGEGVIFNCHVEFPNDHPVPYVLQWDKKVSET 173
            |.|....::.||:  ||:          .:.|.||.....:|.|....|..|.::.|.|..:...
  Fly    71 LAAAEELSNLIPDNYDAIDPVFDNTTDREVIAALGTTARLHCRVRHLGDRAVSWIRQRDLHILTI 135

  Fly   174 GSDLPIYIWYESY-PEHIEEGYKGRVSRVSQDSPFGSASLNLTNIRESDQGWYECKVVFLNRDPK 237
            |  :..|...:.: ..||:..              ....|.:.::::.|.|.|||:|   :.:||
  Fly   136 G--IMTYTNDQRFLARHIDNS--------------DEWVLKIVSVQQRDAGVYECQV---STEPK 181

  Fly   238 ---QHKNGTWFHLDVHAPPRFSVTPEDIIYVNLGDSIILNCQADGTPTP--EILWYKDANPVDPS 297
               .:|.       |....:..:.....:::..|..|.|.|.|...|.|  .:||:||...|..|
  Fly   182 ISLAYKL-------VVVTSKAQILANRELFIQSGSDINLTCIAPQAPGPYTHMLWHKDTELVSDS 239

  Fly   298 PTVGIFNDG------TELRISTIRHEDIGEYTCIARNGEG---------QVSHTAR--------- 338
            ...||..:.      :.|.||.::|.|.|.|||.|.|...         ...|.|.
  Fly   240 ARGGIRVESEQQMKTSNLVISRVQHTDSGNYTCSADNSNSDSVFVHIIKSEQHAAMQHELGSRLL 304

  Fly   339 ------VIIAGGAVIMVPPTNQTKL 357
                  :::|...|:::.||:..::
  Fly   305 LPPLPLLLLAVLLVVLLGPTSSLQI 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tutl	NP_001303307.1	V-set	137..250	CDD:284989	23/116 (20%)
		IG_like	137..229	CDD:214653	19/92 (21%)
		I-set	253..341	CDD:254352	28/119 (24%)
		IGc2	268..331	CDD:197706	26/70 (37%)
		I-set	346..437	CDD:254352	3/12 (25%)
		Ig	349..437	CDD:299845	2/9 (22%)
		Ig	459..530	CDD:299845
		IG_like	549..628	CDD:214653
		IGc2	551..617	CDD:197706
		FN3	633..725	CDD:238020
		FN3	786..874	CDD:238020
dpr5	NP_650080.3	V-set	95..191	CDD:284989	24/121 (20%)
		IG_like	98..179	CDD:214653	20/99 (20%)
		IG_like	206..278	CDD:214653	26/71 (37%)
		Ig	211..278	CDD:143165	25/66 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810