DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tutl and Ama

DIOPT Version :9

Sequence 1:	NP_001303307.1	Gene:	tutl / 46015	FlyBaseID:	FBgn0010473	Length:	1536	Species:	Drosophila melanogaster
Sequence 2:	NP_731114.2	Gene:	Ama / 40831	FlyBaseID:	FBgn0000071	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	343	Identity:	95/343 - (27%)
Similarity:	141/343 - (41%)	Gaps:	64/343 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 VLVSLLALLAKN----AQAHNIPEDAVHITAILGEGVIFNCHVEFPNDHPVPYVLQWDKKVSETG 174
            :|:.|:..||.:    ..|..|.:.:..:.|.:|:.|.|||.||......|    .|.|:.||:.
  Fly    14 LLIGLIFCLAISLDSVLSAPVISQISKDVVASVGDSVEFNCTVEEVGQLSV----SWAKRPSESD 74

  Fly   175 SD-----------LPIYIWYESYPEHIEEGYKGRVSRVSQDSPFGSA--SLNLTNIRESDQGWYE 226
            ::           ||    .:.|...:.||.|           .|||  :..:.||..||.|.||
  Fly    75 TNSVVLSMRNILSLP----DQRYNVTVTEGPK-----------TGSAIYTFRIQNIEVSDMGPYE 124

  Fly   227 CKVVFLNRDPKQHKNGTWFHLDVHAPPRFSV-TPEDIIYVNLGDSIILNCQADGTPTPEILWYKD 290
            |:|:....:....|    ..|.:..||..:. ||:..: |..|.::.|.|.|:|.|.|.|.|.::
  Fly   125 CQVLVSATEKVTKK----LSLQIKTPPVIAENTPKSTL-VTEGQNLELTCHANGFPKPTISWARE 184

  Fly   291 ANPVDPS-------PTVGIFNDGTELRISTIRHEDIGEYTCIARNGEGQV-SHTARVIIAGGAVI 347
            .|.|.|:       ||         |||.::...|.|.|.|||:|||||. ....||.:.....|
  Fly   185 HNAVMPAGGHLLAEPT---------LRIRSVHRMDRGGYYCIAQNGEGQPDKRLIRVEVEFRPQI 240

  Fly   348 MVPPTNQTKLEGEKVIFSCEAKAMPGNVTVRWYREGSPVREVAALETRVTIRKDGS----LIINP 408
            .|......::........|..:..|. .||.|::.|.|::.....|...|....|:    |.|:.
  Fly   241 AVQRPKIAQMVSHSAELECSVQGYPA-PTVVWHKNGVPLQSSRHHEVANTASSSGTTTSVLRIDS 304

  Fly   409 IKPDDSGQYLCEVTNGIG 426
            :..:|.|.|.|..||.:|
  Fly   305 VGEEDFGDYYCNATNKLG 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tutl	NP_001303307.1	V-set	137..250	CDD:284989	33/125 (26%)
		IG_like	137..229	CDD:214653	30/104 (29%)
		I-set	253..341	CDD:254352	34/96 (35%)
		IGc2	268..331	CDD:197706	25/69 (36%)
		I-set	346..437	CDD:254352	21/85 (25%)
		Ig	349..437	CDD:299845	20/82 (24%)
		Ig	459..530	CDD:299845
		IG_like	549..628	CDD:214653
		IGc2	551..617	CDD:197706
		FN3	633..725	CDD:238020
		FN3	786..874	CDD:238020
Ama	NP_731114.2	I-set	33..143	CDD:254352	34/132 (26%)
		Ig	37..127	CDD:299845	30/108 (28%)
		IG_like	154..234	CDD:214653	32/89 (36%)
		IGc2	161..223	CDD:197706	25/70 (36%)
		I-set	254..330	CDD:254352	19/70 (27%)
		IGc2	254..322	CDD:197706	18/68 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810