DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tutl and dpr10

DIOPT Version :9

Sequence 1:	NP_001303307.1	Gene:	tutl / 46015	FlyBaseID:	FBgn0010473	Length:	1536	Species:	Drosophila melanogaster
Sequence 2:	NP_729591.1	Gene:	dpr10 / 39180	FlyBaseID:	FBgn0052057	Length:	408	Species:	Drosophila melanogaster

Alignment Length:	367	Identity:	79/367 - (21%)
Similarity:	125/367 - (34%)	Gaps:	128/367 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   351 PTNQTKLEGEKVIFSCEAKAMPGNVTVRWYREGSPVREVAALETRVTIRKDGSLIINPIKPDDSG 415
            |.|.|.|.|:.....|..|.: ||.||.|.|.    |::..|..                    |
  Fly    60 PRNITSLVGKSAYLGCRVKHL-GNKTVAWIRH----RDLHILTV--------------------G 99

  Fly   416 QYLCEVTNGIGDPQSASAYLSVEYPAKVTFTPTVQYLPFRLAGVVQCYIKSSPQLQYV------- 473
            .|    |.........|.:..::     .:|..:::...|.|||.:|.|.:.|...|.
  Fly   100 TY----TYTTDQRFQTSYHRDID-----EWTLQIKWAQQRDAGVYECQISTQPVRSYSVNLNIVD 155

  Fly   474 ---TWTKDKRLLEPYQMKDIVVMANGSLLFTRVNEEHQGQYACTPYNAQGTAGASGVMDVLVRKP 535
               ..|.|  :::.|...|...:|. :.::...|:|..|.:......|..||...|..|:.|.|
  Fly   156 LIDAETSD--IMQQYYNDDAFYIAE-NRVYQSSNDEFAGMFGPIQTVAVPTATILGGPDLYVDK- 216

  Fly   536 PAFTVEPETLYQRKVGDSVEMHCDALEAEGTERPT-IKWQRQEGEQLTESQRNRIKISGGNITIE 599
                           |.::.:.|  :.....|.|| |.|..|: :.|:|      :.|||.:..:
  Fly   217 ---------------GSTINLTC--IIKFSPEPPTHIFWYHQD-KVLSE------ETSGGRLKFK 257

  Fly   600 NLRRED--------------FGYYQCVVSN-EVATLMAVTQLVIEGTQPH------APYNIT--- 640
            .::.|:              .|.|.|..|| |:|::..   .|::|.:|.      ||..:.
  Fly   258 TIKSEETKSILLIYDADLLHSGKYSCYPSNTEIASIRV---HVLQGERPEAMQTNAAPAAVALAC 319

  Fly   641 -----GKATE------------------SSITLQWLPGYSGG 659
                 |:||:                  ||:.||     |||
  Fly   320 WSCHFGQATQAVRVISTMVAALVLLEACSSLLLQ-----SGG 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tutl	NP_001303307.1	V-set	137..250	CDD:284989
		IG_like	137..229	CDD:214653
		I-set	253..341	CDD:254352
		IGc2	268..331	CDD:197706
		I-set	346..437	CDD:254352	19/85 (22%)
		Ig	349..437	CDD:299845	19/85 (22%)
		Ig	459..530	CDD:299845	17/80 (21%)
		IG_like	549..628	CDD:214653	21/94 (22%)
		IGc2	551..617	CDD:197706	19/81 (23%)
		FN3	633..725	CDD:238020	13/59 (22%)
		FN3	786..874	CDD:238020
dpr10	NP_729591.1	Ig	63..143	CDD:299845	24/113 (21%)
		IG_like	210..297	CDD:214653	24/114 (21%)
		IGc2	217..287	CDD:197706	17/78 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810