DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tutl and dpr20

DIOPT Version :9

Sequence 1:	NP_001303307.1	Gene:	tutl / 46015	FlyBaseID:	FBgn0010473	Length:	1536	Species:	Drosophila melanogaster
Sequence 2:	NP_612066.1	Gene:	dpr20 / 38101	FlyBaseID:	FBgn0035170	Length:	525	Species:	Drosophila melanogaster

Alignment Length:	406	Identity:	82/406 - (20%)
Similarity:	146/406 - (35%)	Gaps:	113/406 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 ALSTQHNTEKSKEQQQQS--------QPLEIPEQRASKCRGDIDR---------------TTTTT 56
            |:..|.::.|.::.:..|        .|...|:....|......:               ||::.
  Fly   131 AILDQDSSMKGQDMESLSLQAGSGTVSPKSSPDSSGHKKNASFQQIGSQNVNALVPATVATTSSG 195

  Fly    57 IPASKTLT-ASPAKTAAFTVKTTRRRRSRRRAEGSSICV----PIRRGQGSTPTPTIQVLQFVLV 116
            :|:|...: |:|.:.|        |.||......|::.|    |:.:|| .|..|   :|.::..
  Fly   196 LPSSSNASLATPTEPA--------RNRSTGLVRNSAVKVDSKHPLSKGQ-KTDAP---MLNYIFD 248

  Fly   117 SLLALLAKNAQAHNIPE--------------DAVHITAILGEGVIFNCHVEFPNDHPVPYV---L 164
            :.     .:|..|:..:              .|.::|...|..:..||.:....|..|.:|   .
  Fly   249 TF-----SSANKHHHHDQRYGPHFEDVQRIGQATNLTVQAGSSIHLNCRISLLQDKTVSWVRHNT 308

  Fly   165 QWDKKVSETGSDLPIYIWYESYPEHIEEGYKGRVSRVSQDSPFGSASLNLTNIRESDQGWYECKV 229
            |.:.|.:....|| :.:...:|..  ::.||     :....| .:..|.:||:::.|:..|||::
  Fly   309 QDEGKDNGNALDL-LTVGMHTYTG--DKRYK-----MEFQYP-NNWRLKITNVKKDDEAIYECQI 364

  Fly   230 VFLNRDPKQHKNGTWFHLDVHAPPRFSV----TPEDIIYVNLGDSIILNCQADGTP-TPEILWYK 289
              ....|:..:    .:|.|:||....|    .|....|..:..::.|:|...... |..::::|
  Fly   365 --STHPPRVIQ----INLHVNAPKVMIVDEVGDPLQEKYYEIDSTLQLSCVVRNVAMTSSVVFWK 423

  Fly   290 --------DANPVDPSPTVGIFNDG--TELRISTIRHEDIGEYTCIAR------------NGE-- 330
                    |......|....:..||  :.|.|:.|...|.|.|||...            |||
  Fly   424 HMDNILNYDVTRGGVSVKTELMEDGANSTLSIAKISKTDSGNYTCSISEFQNFTIVVHILNGESF 488

  Fly   331 GQVSHTARVIIAGGAV 346
            .::.|       ||||
  Fly   489 AELHH-------GGAV 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tutl	NP_001303307.1	V-set	137..250	CDD:284989	24/115 (21%)
		IG_like	137..229	CDD:214653	22/94 (23%)
		I-set	253..341	CDD:254352	23/116 (20%)
		IGc2	268..331	CDD:197706	19/87 (22%)
		I-set	346..437	CDD:254352	1/1 (100%)
		Ig	349..437	CDD:299845
		Ig	459..530	CDD:299845
		IG_like	549..628	CDD:214653
		IGc2	551..617	CDD:197706
		FN3	633..725	CDD:238020
		FN3	786..874	CDD:238020
dpr20	NP_612066.1	IG_like	278..365	CDD:214653	22/97 (23%)
		Ig	279..378	CDD:299845	24/113 (21%)
		Ig	400..471	CDD:299845	16/70 (23%)
		IG_like	402..480	CDD:214653	16/77 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810