Protein Alignment tutl and ihog

DIOPT Version :9

• Sequence 1: NP_001303307.1
• Gene: tutl / 46015
• FlyBaseID: FBgn0010473
• Length: 1536
• Species: Drosophila melanogaster
• Sequence 2: NP_609085.1
• Gene: ihog / 33972
• FlyBaseID: FBgn0031872
• Length: 886
• Species: Drosophila melanogaster
• Alignment Length: 970
• Identity: 201/970 - (20%)
• Similarity: 343/970 - (35%)
• Gaps: 244/970 - (25%)

  Fly   250 HAPP--RFSVTPEDIIYVNLGDSIILNCQADGTPTPEILWYKDANPVDPSPTVGIFNDGT----- 307
            |..|  |....||.:: ..|||.::|.|:.  :..||...:...:...|.........||
  Fly    48 HPSPGVRILRAPESLV-APLGDEVVLECET--SLQPERFEWSHRSSRSPGAGFKYLKTGTAKANV 109

  Fly   308 --ELRIS----TIRHEDIGEYTCIARNGEGQVSHT-ARVIIAGGAVI----MVPPTNQTKLEGEK 361
              |..||    .:|.:.:|||.|:...|...|:.| ||:.:|..:::    ...|.......|..
  Fly   110 SQEAAISRLRVLVRPDTLGEYRCVGWFGPLVVTSTIARLELASTSLVDAQESESPLQWRVSAGNS 174

  Fly   362 VIFSCEAKAMPGNVTVRW--YREGSPVREVAALETRVTIRKDGSLIINPIKPDDSGQYLCEVTNG 424
            |::|| .:.:..|.:..|  ||.|..::.       ..|..:|:|.::.:..:.||.|.|:.||
  Fly   175 VLWSC-GQQVQSNPSASWSYYRNGVEIKP-------EFIGTNGNLFLSNVSSESSGSYSCQATN- 230

  Fly   425 IGDPQSASAYLSVEYPAKVTFTPTVQYLPFRLAGVVQCYIKSSPQLQYVTWTKDKRLL------- 482
               |.|..   .::.|..:....|.:.   |........::..|..|.:|..:...||
  Fly   231 ---PASGE---RIQLPGSLQLQVTPEQ---RSESKSPHLLRGQPSSQEITIREGSSLLLLCPGVG 286

  Fly   483 EP-----YQMKDIV--VMANGSLLF--------TRVNEEHQGQYACTPYNAQGTAGASGVMDVLV 532
            .|     :...|:|  |....|.:|        ||||:  .|.|.|...|....| ....:.|.|
  Fly   287 SPPPTVVWSSPDVVGAVKNKRSKVFGHALEISNTRVND--AGTYICFQDNGVRPA-LEHYIKVHV 348

  Fly   533 RKPPAFTVEPETLYQRKVGDSVEMHCDALEAEGTERPTIKWQRQEGEQLTESQRNRIKISGGNIT 597
            .:||.. |.|........||.:::.|   :|.|...|.|.|.......:.:|:   .::|...:.
  Fly   349 EQPPQI-VRPPWADLTNEGDRLKLEC---KATGVPTPEIYWLLNGHSSIDDSE---AELSNNFLI 406

  Fly   598 IENLRREDFGYYQCVVSNEV-----ATLMAVTQLVIE------GTQ--------------PHAPY 637
            :.::.:...||.||...|.:     .||:.|....|:      ||.              |..|.
  Fly   407 LHSVLKRHAGYVQCFARNRLGEHSAGTLLQVNPKQIQEPRESGGTHRPKPNQGSRQKQMYPPTPP 471

  Fly   638 NITGKATESSITLQWLPGYSGGSE---YKQDYTIWFREAGV-NDWQTISVT-PSG---------- 687
            |:| :.::.|:.|:|:...:.|..   :|..|    |..|. .:|||.:.. |.|
  Fly   472 NVT-RLSDESVMLRWMVPRNDGLPIVIFKVQY----RMVGKRKNWQTTNDNIPYGKPKWNSELGK 531

  Fly   688 STQVTINGLASGTTYEFQVVGRNVLGDGMMSKVMTVRTLEDAPAAPRNVKAATQPPDSFFQLMP- 751
            |...::..|....||.|              :::.|.:..|...:..:.|...| |.:....||
  Fly   532 SFTASVTDLKPQHTYRF--------------RILAVYSNNDNKESNTSAKFYLQ-PGAALDPMPV 581

  Fly   752 ------------------------DEADLLAYFDIYFHTDSRGTLVYSPPKLRVKGPKPGPPRNV 792
                                    ||..:..|:..|..:.|.|...    |..::|..
  Fly   582 PELLEIEEYSETAVVLHWSLASDADEHLITGYYAYYRPSSSAGEYF----KATIEGAH------- 635

  Fly   793 SVTEVSNGFLITWQSPLERAHIVKF--YTIKYRTDAQWKTLNRGQI-RPEETQYLVKNLVGGRTY 854
                 :..|.|   :|||.|.:.:|  .:....:.:::..|.:|:. ||:.:......|..|
  Fly   636 -----ARSFKI---APLETATMYEFKLQSFSAASASEFSALKQGRTQRPKTSTTEEPTLQMG--- 689

  Fly   855 YFRVLANSEKSYESSDEVKFPVPARVKHKAITAGVVGGILFFIVAIILSVCAVKICNKRKRRKQE 919
                  :.:.:..|.:|.....|      .:|..:.||.:  ::.:::|.|   .|..|:|..:.
  Fly   690 ------DRDTTTPSHNETFNMSP------MLTGTIGGGAV--LILLLISTC---FCVCRRRNSRS 737

  Fly   920 KEFNMVACRITDARNIAANNHHLHNRSTGSISSGQVPLKKYKQTRISSLTAILIAILHWIWPPDR 984
            :..|....|:.:.|:...        ..|:.|    |.|:.::||...:|
  Fly   738 RGNNPNKPRMAELRDDFV--------PLGNCS----PTKQRQRTRHIHIT--------------- 775

  Fly   985 CTNCHSIYSSPNLEDGDEDDGGGGRRRSVSRIQR--SLDGRFVLDVEGVSKLGYSQQTLESGNVD 1047
             .|..:......||:.::.|      :.....||  |.|....|.....|.|..||:|||..
  Fly   776 -LNPLAQQQQQALEEKNDTD------QDAPYYQRPSSYDYDPTLRRMSSSSLRRSQRTLERA--- 830

  Fly  1048 VVDGGLFERRNSNVSQKSSSDDGGFLSRRNFITARASWRRPLVASSSQLSLQSAADSARG 1107
               ||.....|.|.:..:.|.:.|.:.... ...|...:||.::|.|: :|.|.:.::.|
  Fly   831 ---GGSNGSNNGNNNNLNQSAEAGSIENPG-KPGRVLMKRPRLSSRSE-NLSSGSLNSVG 885

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tutl	NP_001303307.1	V-set	137..250	CDD:284989	201/970 (21%)
		IG_like	137..229	CDD:214653
		I-set	253..341	CDD:254352	27/101 (27%)
		IGc2	268..331	CDD:197706	18/73 (25%)
		I-set	346..437	CDD:254352	21/96 (22%)
		Ig	349..437	CDD:299845	21/89 (24%)
		Ig	459..530	CDD:299845	20/92 (22%)
		IG_like	549..628	CDD:214653	18/83 (22%)
		IGc2	551..617	CDD:197706	15/65 (23%)
		FN3	633..725	CDD:238020	23/106 (22%)
		FN3	786..874	CDD:238020	15/90 (17%)
ihog	NP_609085.1	IG_like	59..145	CDD:214653	22/88 (25%)
		ig	265..330	CDD:278476	17/66 (26%)
		IG_like	267..348	CDD:214653	20/83 (24%)
		Ig	314..>377	CDD:299845	19/69 (28%)
		IG_like	364..437	CDD:214653	17/78 (22%)
		IGc2	365..427	CDD:197706	15/67 (22%)
		FN3	467..565	CDD:238020	24/116 (21%)
		fn3	580..655	CDD:278470	16/93 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452278
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840