DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tutl and DIP-eta

DIOPT Version :9

Sequence 1:	NP_001303307.1	Gene:	tutl / 46015	FlyBaseID:	FBgn0010473	Length:	1536	Species:	Drosophila melanogaster
Sequence 2:	NP_001188701.2	Gene:	DIP-eta / 33793	FlyBaseID:	FBgn0031725	Length:	450	Species:	Drosophila melanogaster

Alignment Length:	371	Identity:	97/371 - (26%)
Similarity:	161/371 - (43%)	Gaps:	80/371 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 QVLQFVLVSLLALLAKNA--QAHNIPEDA----------VHITAILGEGVIFNCHVEFPNDHPVP 161
            |.....::.||.|:::..  |...:|.:.          |::||.:|......|.|:...    |
  Fly    11 QTCALSVILLLILMSQQCYPQRVEVPAEVIVDPKFSSPIVNMTAPVGRDAFLTCVVQDLG----P 71

  Fly   162 YVLQWDKKVSETGSDLPIYIWYESYPEHIEEGYKGRVSRVSQDSPFGSA-------SLNLTNIRE 219
            |.:.|.:..::|         ..:...|:          ::::...|.|       ::.:.:|:|
  Fly    72 YKVAWLRVDTQT---------ILTIQNHV----------ITKNQRIGIANSEHKTWTMRIKDIKE 117

  Fly   220 SDQGWYECKVVFLNRDPKQHKNGTWFHLDVHAPPRF--SVTPEDIIYVNLGDSIILNCQADGTPT 282
            ||:|||.|::   |.||.:.:.|   :|||..||..  ..|..|:: |..|.::.|.|.|.|:|.
  Fly   118 SDKGWYMCQI---NTDPMKSQMG---YLDVVVPPDILDYPTSTDMV-VREGSNVTLKCAATGSPE 175

  Fly   283 PEILWYKDAN-PVDPSPTVGIFN-DGTELRISTIRHEDIGEYTCIARNGEGQVSHTARVIIAGGA 345
            |.|.|.:::. |::.:....:.: :||:|.|..:|...:|.|.|||.||. ..|.:.|:.:
  Fly   176 PTITWRRESGVPIELATGEEVMSIEGTDLVIPNVRRHHMGAYLCIASNGV-PPSVSKRITL---- 235

  Fly   346 VIMVPP--TNQTKL----EGEKVIFSCEAKAMPGNVTVRWYRE-GSPVREVAALETRVT----IR 399
            |:..||  |.|.:|    ||:.|...||::|.|.::.. |.|| |..|.........||    .|
  Fly   236 VVHFPPMITVQNQLIGAVEGKGVTLDCESEAYPKSINY-WTRERGEIVPPGGKYSANVTEIGGYR 299

  Fly   400 KDGSLIINPIKPDDSGQYLCEVTNGIGD----------PQSASAYL 435
            ....|.|||:...:.|.|.|...|.:||          |.:|..|:
  Fly   300 NSMRLHINPLTQAEFGSYRCVAKNSLGDTDGTIKLYRIPPNAVNYV 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tutl	NP_001303307.1	V-set	137..250	CDD:284989	26/119 (22%)
		IG_like	137..229	CDD:214653	20/98 (20%)
		I-set	253..341	CDD:254352	28/91 (31%)
		IGc2	268..331	CDD:197706	22/64 (34%)
		I-set	346..437	CDD:254352	34/111 (31%)
		Ig	349..437	CDD:299845	33/108 (31%)
		Ig	459..530	CDD:299845
		IG_like	549..628	CDD:214653
		IGc2	551..617	CDD:197706
		FN3	633..725	CDD:238020
		FN3	786..874	CDD:238020
DIP-eta	NP_001188701.2	Ig	51..141	CDD:299845	25/118 (21%)
		IG_like	51..137	CDD:214653	23/111 (21%)
		IG_like	153..237	CDD:214653	26/89 (29%)
		Ig	161..224	CDD:299845	20/62 (32%)
		IG_like	252..335	CDD:214653	25/83 (30%)
		Ig	258..333	CDD:143165	23/75 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810