DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tutl and dpr4

DIOPT Version :9

Sequence 1:	NP_001303307.1	Gene:	tutl / 46015	FlyBaseID:	FBgn0010473	Length:	1536	Species:	Drosophila melanogaster
Sequence 2:	NP_001014616.2	Gene:	dpr4 / 3346160	FlyBaseID:	FBgn0053512	Length:	323	Species:	Drosophila melanogaster

Alignment Length:	266	Identity:	61/266 - (22%)
Similarity:	97/266 - (36%)	Gaps:	51/266 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 ITAILGEGVIFNCHVEFPNDHPVPYVLQWDKKVSETGSDLPIYIWYESYPEHIEEGYKGRVSRVS 202
            :||.:|:..:.:|.|....|..|.::.:.|..:...|  :..|...:.:.....||......|:|
  Fly    55 VTATVGQAALLHCRVRNLGDRAVSWIRKRDLHILTVG--ILTYTNDQRFQSLHSEGSDEWTLRIS 117

  Fly   203 QDSPFGSASLNLTNIRESDQGWYECKVVFLNRDPKQHKNGTWFHLDVHAPPRFSVTPEDIIYVNL 267
            ...|             .|.|.|||:|   :.:||..:.   |.|:| ...|..:.....:::..
  Fly   118 SPQP-------------RDSGTYECQV---STEPKISQG---FRLNV-VVSRAKILGNAELFIKS 162

  Fly   268 GDSIILNCQADGTPTPE--ILWYKDANPVDPSPTVGIFNDGTE-------LRISTIRHEDIGEYT 323
            |..|.|.|.|..:|.|.  |.|||....::.|...|| |..||       |.|:.....|.|.||
  Fly   163 GSDINLTCLAMQSPVPPSFIYWYKGKRVMNYSQRGGI-NVITERSTRTSKLLIAKATPADSGNYT 226

  Fly   324 CIAR------------NGEGQVSHTARVIIAGGAVIMVPPTNQTKLE---GEKVIFSCEAKAMPG 373
            |...            |||    |.|.:.....:...:.|.:.|.:.   ...:..:..:.|...
  Fly   227 CSPSSSDSASVVVHVINGE----HPAAMQHGNSSATCLRPLSSTSVPFVLATWMSMTVASVAWNS 287

  Fly   374 NVTVRW 379
            |:.:.|
  Fly   288 NLNINW 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tutl	NP_001303307.1	V-set	137..250	CDD:284989	25/111 (23%)
		IG_like	137..229	CDD:214653	20/90 (22%)
		I-set	253..341	CDD:254352	30/108 (28%)
		IGc2	268..331	CDD:197706	26/83 (31%)
		I-set	346..437	CDD:254352	5/37 (14%)
		Ig	349..437	CDD:299845	5/34 (15%)
		Ig	459..530	CDD:299845
		IG_like	549..628	CDD:214653
		IGc2	551..617	CDD:197706
		FN3	633..725	CDD:238020
		FN3	786..874	CDD:238020
dpr4	NP_001014616.2	V-set	53..146	CDD:284989	26/112 (23%)
		IG_like	53..145	CDD:214653	25/110 (23%)
		ig	153..227	CDD:278476	22/74 (30%)
		IG_like	161..>227	CDD:214653	22/66 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810