DRSC/TRiP Functional Genomics Resources

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Protein Alignment tutl and Negr1

DIOPT Version :9

Sequence 1:NP_001303307.1 Gene:tutl / 46015 FlyBaseID:FBgn0010473 Length:1536 Species:Drosophila melanogaster
Sequence 2:XP_036019026.1 Gene:Negr1 / 320840 MGIID:2444846 Length:362 Species:Mus musculus


Alignment Length:329 Identity:84/329 - (25%)
Similarity:121/329 - (36%) Gaps:62/329 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   261 DIIYVNLGDSIILNCQ-ADGTPTPEILWYK---------DANPVDPSPTVGIFND-GTELRISTI 314
            |.:.|..||:.:|.|. .||  ..:..|..         |...|||..::...|. ...|:|..:
Mouse    40 DNMLVRKGDTAVLRCYLEDG--ASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNV 102

  Fly   315 RHEDIGEYTCIARNGEGQVSHTARVIIAGGAVIMVPP------TNQTKLEGEKVIFSCEAKAMPG 373
            ...|.|.|||..     |..||.|.:.. ...:.|||      .:.|..||..|..:|.|...|.
Mouse   103 DVTDDGPYTCSV-----QTQHTPRTMQV-HLTV
QVPPKIYDISNDMTINEGTNVTLTCLATGKPE 161

  Fly   374 NVTVRWYREGSPVREVAALETRVTIRKDGSLIINPIKPDDSGQYLCEVTNGIGDPQSASAYLSVE 438
            .| :.| |..||        :.........|.|..|..|.:|:|.|...|.:..|......:.  
Mouse   162 PV-ISW-RHISP--------SAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVKKVRVI-- 214

  Fly   439 YPAKVTFTPTVQYL------PFRLAGVVQCYIKSSPQLQYVTWTKDKRLLEPYQMKDIVVMANGS 497
                |.|.||:|.:      |.| :|:::|.....|...:..:..:|||....|.   :::.|.|
Mouse   215 ----VNFAPTIQEIKSGTVTPGR-SGLIRCEGAGVPPPAFEWYKGEKRLFNGQQG---IIIQNFS 271

  Fly   498 ----LLFTRVNEEHQGQYACTPYNAQGTAGASGVMDVLVR---KPPAFTVEPETLYQRKVGDSVE 555
                |..|.|.:||.|.|.|...|..||..||..::.::.   ..|..:..|.|......|.:  
Mouse   272 TRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNQIIEPTTSSPVTSPAPSTAQYGITGSA-- 334

  Fly   556 MHCD 559
              ||
Mouse   335 --CD 336

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tutlNP_001303307.1 V-set 137..250 CDD:284989
IG_like 137..229 CDD:214653
I-set 253..341 CDD:254352 25/90 (28%)
IGc2 268..331 CDD:197706 19/73 (26%)
I-set 346..437 CDD:254352 24/96 (25%)
Ig 349..437 CDD:299845 24/93 (26%)
Ig 459..530 CDD:299845 21/74 (28%)
IG_like 549..628 CDD:214653 3/11 (27%)
IGc2 551..617 CDD:197706 3/9 (33%)
FN3 633..725 CDD:238020
FN3 786..874 CDD:238020
Negr1XP_036019026.1 FR1 38..55 CDD:409353 5/14 (36%)
Ig strand A' 40..46 CDD:409353 2/5 (40%)
IG_like 41..129 CDD:214653 24/95 (25%)
Ig strand B 48..56 CDD:409353 3/7 (43%)
CDR1 56..60 CDD:409353 2/5 (40%)
FR2 61..68 CDD:409353 1/6 (17%)
Ig strand C 61..67 CDD:409353 1/5 (20%)
CDR2 69..79 CDD:409353 1/9 (11%)
Ig strand C' 71..74 CDD:409353 0/2 (0%)
Ig strand C' 76..79 CDD:409353 1/2 (50%)
FR3 80..115 CDD:409353 11/39 (28%)
Ig strand D 84..91 CDD:409353 0/6 (0%)
Ig strand E 94..100 CDD:409353 1/5 (20%)
Ig strand F 107..115 CDD:409353 4/12 (33%)
CDR3 116..120 CDD:409353 1/3 (33%)
Ig strand G 120..129 CDD:409353 1/9 (11%)
FR4 122..129 CDD:409353 0/7 (0%)
Ig strand A' 139..144 CDD:409353 0/4 (0%)
IGc2 146..204 CDD:197706 19/67 (28%)
Ig strand B 150..157 CDD:409353 2/6 (33%)
Ig strand C 163..168 CDD:409353 2/6 (33%)
Ig strand C' 170..172 CDD:409353 2/9 (22%)
Ig strand E 180..186 CDD:409353 2/5 (40%)
Ig strand F 193..200 CDD:409353 3/6 (50%)
Ig_3 219..295 CDD:404760 22/79 (28%)
putative Ig strand A 219..225 CDD:409353 3/5 (60%)
Ig strand B 235..239 CDD:409353 1/3 (33%)
Ig strand C 248..252 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 1/3 (33%)
Ig strand F 288..293 CDD:409353 2/4 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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