DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tutl and dpr1

DIOPT Version :9

Sequence 1:	NP_001303307.1	Gene:	tutl / 46015	FlyBaseID:	FBgn0010473	Length:	1536	Species:	Drosophila melanogaster
Sequence 2:	NP_001286645.1	Gene:	dpr1 / 2768858	FlyBaseID:	FBgn0040726	Length:	367	Species:	Drosophila melanogaster

Alignment Length:	262	Identity:	63/262 - (24%)
Similarity:	103/262 - (39%)	Gaps:	52/262 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 RGQGSTPTPTIQVLQFVLVSLLALLAKNAQAHNIPEDAVHITAILGEGVIFNCHVEFPNDHPVPY 162
            ||..:...||........:|...||.  ....::|.   ::|..:|:....:|.||...|..|.:
  Fly    28 RGYNAALAPTPPTTSTTTISPSNLLP--YFDFDVPR---NLTVTVGQTGFLHCRVERLGDKDVSW 87

  Fly   163 VLQWDKKVSETGSDLPIYIWYESYPEHIEEGYKGRVSRVSQDSPFGSA--SLNLTNIRESDQGWY 225
            :.:.|..:...|...     |.|       ..:.:|.|     |.|||  :|.:...:..|.|.|
  Fly    88 IRKRDLHILTAGGTT-----YTS-------DQRFQVLR-----PDGSANWTLQIKYPQPRDSGVY 135

  Fly   226 ECKVVFLNRDPKQHKNGTWFHLDVHAPPRFSVTPEDIIYVNLGDSIILNCQADGTP--TPEILWY 288
            ||::   |.:||...:.|:..:::.|.   ...|.|:: |..|..|.|.|:....|  ...|.||
  Fly   136 ECQI---NTEPKMSLSYTFNVVELKAE---IFGPSDLM-VKTGSDINLTCKIMQGPHELGNIFWY 193

  Fly   289 KDA--------NPVDPS-PTVGIFNDGTE-----LRISTIRHEDIGEYTCIARNGEGQVSHTARV 339
            |.:        |.:|.| ..:.:.:|.|:     |:|......|.|.|||:.     .|:.|:.|
  Fly   194 KGSEMLDGKGENEIDSSMARIRVEDDWTDGLTSRLKIKRAMPGDTGNYTCVP-----TVAKTSSV 253

  Fly   340 II 341
            .:
  Fly   254 YV 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tutl	NP_001303307.1	V-set	137..250	CDD:284989	27/114 (24%)
		IG_like	137..229	CDD:214653	23/93 (25%)
		I-set	253..341	CDD:254352	27/103 (26%)
		IGc2	268..331	CDD:197706	21/78 (27%)
		I-set	346..437	CDD:254352
		Ig	349..437	CDD:299845
		Ig	459..530	CDD:299845
		IG_like	549..628	CDD:214653
		IGc2	551..617	CDD:197706
		FN3	633..725	CDD:238020
		FN3	786..874	CDD:238020
dpr1	NP_001286645.1	Ig	59..154	CDD:299845	28/117 (24%)
		IG_like	60..150	CDD:214653	27/112 (24%)
		IG_like	163..257	CDD:214653	27/99 (27%)
		Ig	174..244	CDD:143165	19/69 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810