DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tutl and zig-2

DIOPT Version :9

Sequence 1:	NP_001303307.1	Gene:	tutl / 46015	FlyBaseID:	FBgn0010473	Length:	1536	Species:	Drosophila melanogaster
Sequence 2:	NP_510069.1	Gene:	zig-2 / 192087	WormBaseID:	WBGene00006979	Length:	238	Species:	Caenorhabditis elegans

Alignment Length:	220	Identity:	56/220 - (25%)
Similarity:	88/220 - (40%)	Gaps:	38/220 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   247 LDVHAPPRFSVTPEDIIYVNLGDSIILNCQADGTPTPEILWYKDANPVDPSPTVGIF----NDGT 307
            ||.....:|:.||.| ..|..|:..:|:|.|:|.|.|.|.|..:...:....|..::    |||.
Worm    27 LDSQPLLKFTRTPND-SNVTFGEKFVLSCGANGAPLPSIYWELNGMRIQGEETSNVYENILNDGK 90

  Fly   308 EL----------RISTIRHEDIGEYTCIARNGEGQVSHTARVIIAG----------GA-VIMVPP 351
            ::          ||......:.|.|.||..||..::.|.|:|.:.|          || .|.:..
Worm    91 QVSNAAMVSSHYRIPCATARNSGAYKCIIDNGLTKLEHVAKVFVGGNKTNCALNDNGAPFISMTV 155

  Fly   352 TNQTKLEGEKVIFSCEAKAMPGNVTVRW-YREGSPVREVAALETRVTIRKDGSLIINPIKPDDSG 415
            ..:.::....|..||.::     ....| :.:|..:  :.....|..:...|.|||..|...|.|
Worm   156 DFRLEISNNAVALSCRSE-----TATEWSWHKGEQL--LTNDGERYQMFPSGDLIIRNISWSDMG 213

  Fly   416 QYLCEVTNGIGDPQSASAYLSVEYP 440
            :|.|...|..|: .:|..:|   ||
Worm   214 EYNCTARNHFGE-TTAITFL---YP 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tutl	NP_001303307.1	V-set	137..250	CDD:284989	2/2 (100%)
		IG_like	137..229	CDD:214653
		I-set	253..341	CDD:254352	29/101 (29%)
		IGc2	268..331	CDD:197706	21/76 (28%)
		I-set	346..437	CDD:254352	20/91 (22%)
		Ig	349..437	CDD:299845	19/88 (22%)
		Ig	459..530	CDD:299845
		IG_like	549..628	CDD:214653
		IGc2	551..617	CDD:197706
		FN3	633..725	CDD:238020
		FN3	786..874	CDD:238020
zig-2	NP_510069.1	I-set	34..134	CDD:254352	29/100 (29%)
		Ig	34..121	CDD:299845	24/87 (28%)
		Ig	<179..232	CDD:299845	14/55 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810