DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tutl and zig-11

DIOPT Version :9

Sequence 1:	NP_001303307.1	Gene:	tutl / 46015	FlyBaseID:	FBgn0010473	Length:	1536	Species:	Drosophila melanogaster
Sequence 2:	NP_503523.2	Gene:	zig-11 / 189580	WormBaseID:	WBGene00021305	Length:	304	Species:	Caenorhabditis elegans

Alignment Length:	320	Identity:	78/320 - (24%)
Similarity:	109/320 - (34%)	Gaps:	98/320 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 LVSLLALLAKNAQAHNIPEDAVHI----------TAILGEGVIFNCHVEFPNDHPVPYVLQWDKK 169
            |..:|||.|        |.||...          |.|.||. :|:..:              |:.
Worm    12 LAVILALYA--------PSDAATSQKYTAMGNLQTVIHGES-LFSTDI--------------DEN 53

  Fly   170 VSETGSDLPIYIWYESYPEHIEEG---YK---GRVSRVSQDSPF--------GSASLNLTNIRES 220
            ...||     .:|.:     :.||   ||   .|..|:.....|        ..|.|:....:..
Worm    54 RKTTG-----VLWCQ-----VREGTIHYKPTWARFVRIRDQKQFRADIGLDDDKAYLHFGQSKAD 108

  Fly   221 DQGWYECKV-----------VFLNRDPKQHKNGTWFHLDVHAPPRFSVTPEDIIYVNLGDSIILN 274
            ..|.|.|::           :|....|....|.||......:.|...|.|  .:|..|..:..:.
Worm   109 ASGKYRCEIKVPDNSIIIGNMFAYSHPVVKNNETWELKKSESEPFTVVGP--AVYAPLDSAARIQ 171

  Fly   275 CQADGTPTPEILWYKDANPVDPSPTVGIFNDGTELRISTIRHEDIGEYTCIARNG-----EGQVS 334
            |...|.|.|:|:||||..|::....|. |..|. |.|...:.||.|.|.|.|.|.     :|...
Worm   172 CPIVGYPEPQIVWYKDKFPLEIEGRVK-FTAGV-LSIEGAQEEDAGVYRCEATNQFPVQIDGPEQ 234

  Fly   335 HTA-------RVIIAGG-----AVIMVPPTNQTKLEGEKVIFSCEA----KAMPGNVTVR 378
            |.|       |:..:.|     |:|::     ..|....|||:|:.    ||...||..|
Worm   235 HFAVKLDQELRIGDSYGWMLPLAIILI-----ILLLLFLVIFTCQRCAKYKADQYNVADR 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tutl	NP_001303307.1	V-set	137..250	CDD:284989	26/147 (18%)
		IG_like	137..229	CDD:214653	21/115 (18%)
		I-set	253..341	CDD:254352	31/99 (31%)
		IGc2	268..331	CDD:197706	22/67 (33%)
		I-set	346..437	CDD:254352	11/37 (30%)
		Ig	349..437	CDD:299845	10/34 (29%)
		Ig	459..530	CDD:299845
		IG_like	549..628	CDD:214653
		IGc2	551..617	CDD:197706
		FN3	633..725	CDD:238020
		FN3	786..874	CDD:238020
zig-11	NP_503523.2	IGc2	165..223	CDD:197706	21/59 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910