DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tutl and zig-8

DIOPT Version :9

Sequence 1:	NP_001303307.1	Gene:	tutl / 46015	FlyBaseID:	FBgn0010473	Length:	1536	Species:	Drosophila melanogaster
Sequence 2:	NP_499714.1	Gene:	zig-8 / 176732	WormBaseID:	WBGene00006985	Length:	268	Species:	Caenorhabditis elegans

Alignment Length:	290	Identity:	64/290 - (22%)
Similarity:	101/290 - (34%)	Gaps:	113/290 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 CVPIRRGQGSTPTPTIQVLQFVLVSLLALLAKN-AQAH-NIPEDAVHITA--ILGEGVIFNC-HV 152
            |:...|.:...|:.||          :.::|:| |..| ::|.||.|..|  .:.:|.:... :.
Worm    29 CLRQERSRVENPSQTI----------VNVVAENPAYLHCSVPPDAEHEIAWTRVSDGALLTAGNR 83

  Fly   153 EFPNDHPVPYVLQWDKKVSETGSDLPIYIWYESYPEHIEEGYKGRVSRVSQDSPFGSASLNLTNI 217
            .|..|.      :|  :||:..::    ||.                            |||...
Worm    84 TFTRDP------RW--QVSKKSAN----IWV----------------------------LNLRRA 108

  Fly   218 RESDQGWYECKVVFLNRDPKQHKNGTWF--HLDVHAPPRFSVTPEDI------IYVNL-GDSIIL 273
            .:.|.|.|.|::        ..|:.|.:  :|.|..||..|  |..:      :..|: ||.::|
Worm   109 EQQDSGCYLCEI--------NDKHNTVYAVYLKVLEPPLPS--PSSLQKKSTKLMANMSGDEVVL 163

  Fly   274 NCQADGTPTPE----ILWYKDANPVDPSPTVGIFNDGTE----------------LRISTIRHED 318
            ||....|...|    ::|.:|.|.::       ||| ||                :||.....||
Worm   164 NCTVTSTDKDEEVLDVVWTRDGNTIN-------FND-TEKYILKVKRDAGVVIETMRIRKATMED 220

  Fly   319 IGEYTC-----------IARNGEGQVSHTA 337
            .|.|.|           .....|.|.|::|
Worm   221 DGNYACEHSQQKASQIVHINKAEAQTSNSA 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tutl	NP_001303307.1	V-set	137..250	CDD:284989	20/117 (17%)
		IG_like	137..229	CDD:214653	17/94 (18%)
		I-set	253..341	CDD:254352	30/123 (24%)
		IGc2	268..331	CDD:197706	22/93 (24%)
		I-set	346..437	CDD:254352
		Ig	349..437	CDD:299845
		Ig	459..530	CDD:299845
		IG_like	549..628	CDD:214653
		IGc2	551..617	CDD:197706
		FN3	633..725	CDD:238020
		FN3	786..874	CDD:238020
zig-8	NP_499714.1	IG_like	55..134	CDD:214653	24/126 (19%)
		Ig	55..129	CDD:143165	23/121 (19%)
		ig	158..229	CDD:278476	22/78 (28%)
		IG_like	158..227	CDD:214653	21/76 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810