DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tutl and rig-5

DIOPT Version :9

Sequence 1:	NP_001303307.1	Gene:	tutl / 46015	FlyBaseID:	FBgn0010473	Length:	1536	Species:	Drosophila melanogaster
Sequence 2:	NP_001251131.1	Gene:	rig-5 / 172791	WormBaseID:	WBGene00004372	Length:	482	Species:	Caenorhabditis elegans

Alignment Length:	375	Identity:	98/375 - (26%)
Similarity:	149/375 - (39%)	Gaps:	86/375 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 PIRRGQG------STPTPTIQVLQFVLVSLLALLAKNAQAHNIP--------EDAVHITAILGEG 145
            |..||:|      ..|......| |.|:..:.|:.|.|.:...|        ..||   |:||:.
Worm    41 PTFRGRGRFVILFHIPLQEKMYL-FALLCGVLLVFKQACSRGAPPTIQQPSMSSAV---ALLGQD 101

  Fly   146 VIFNCHVEFPNDHPV--------PYVLQWDKKVSETGSDLPIYIWYESYPEHIEEGYKGRVSRVS 202
            |.|.|.|.....|.|        |.:|.:|:||....:.      ||..|         |:..:.
Worm   102 VDFTCIVNDLGSHMVAFVKADSPPRLLSFDEKVFRRRNK------YELKP---------RIGDLH 151

  Fly   203 QDSPFGSASLNLTNIRESDQGWYECKVVFLNRDPKQHKNGTWFHLDVHAPPRFSVTPEDIIYVNL 267
            .:     ..|.:.|::|||:|.|.|::   |.:|.....|   .|||..||..|.:....:.|..
Worm   152 NE-----WVLTIKNVQESDRGNYSCQI---NTEPITLSTG---ELDVKVPPVVSRSTPAAVEVRE 205

  Fly   268 GDSIILNCQADGTPTPEILWYK-DANPVDPSPTVG----IFNDGTELRISTIRHEDIGEYTCIAR 327
            |:::.|.|:|||.|||.::|.: |...:..:...|    :|: |..|.::.:..:.:.||.|:|.
Worm   206 GNNVSLTCKADGNPTPTVIWRRQDRQIIRYNGATGFGASVFH-GPVLHLTKVSRKHMSEYLCVAS 269

  Fly   328 NG-EGQVSHTARVIIAGGAVIMVPPTNQTKLE------GEKVIFSCEAKAMPGNVTVRWYREGSP 385
            || ....|.|.::::.      .||..|.:.|      |......|..:|.| ...:.|.::|.|
Worm   270 NGIPPDESWTVKLLVT------FPPLVQAQSETVQASVGSMARMVCTTEAWP-RPEMGWEKDGEP 327

  Fly   386 VRE---VAALET------RVTIRKDGSLIINPIKPDDSGQYLCEVTNGIG 426
            |.|   ||...|      .|.|     |.|..::....|.|.|...|..|
Worm   328 VYESNNVAMTHTVSGQYHSVHI-----LEIRNVQSSHFGVYRCVAKNDNG 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tutl	NP_001303307.1	V-set	137..250	CDD:284989	31/120 (26%)
		IG_like	137..229	CDD:214653	26/99 (26%)
		I-set	253..341	CDD:254352	26/93 (28%)
		IGc2	268..331	CDD:197706	21/68 (31%)
		I-set	346..437	CDD:254352	25/96 (26%)
		Ig	349..437	CDD:299845	25/93 (27%)
		Ig	459..530	CDD:299845
		IG_like	549..628	CDD:214653
		IGc2	551..617	CDD:197706
		FN3	633..725	CDD:238020
		FN3	786..874	CDD:238020
rig-5	NP_001251131.1	IG_like	92..189	CDD:214653	34/125 (27%)
		Ig_3	191..270	CDD:372822	22/79 (28%)
		IG	294..380	CDD:214652	22/85 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910