DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment tutl and zig-7

DIOPT Version :9

Sequence 1:NP_001303307.1 Gene:tutl / 46015 FlyBaseID:FBgn0010473 Length:1536 Species:Drosophila melanogaster
Sequence 2:NP_491451.2 Gene:zig-7 / 172096 WormBaseID:WBGene00006984 Length:239 Species:Caenorhabditis elegans


Alignment Length:252 Identity:56/252 - (22%)
Similarity:96/252 - (38%) Gaps:68/252 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   108 IQVLQFVLVSLLALLAKNAQAHNIPEDAVHITAILGEGVIFN--CHVEFPNDHPVPYVLQWDKKV 170
            ::::..:.::||..|...:.|        .||.|....|:.:  .||..||.             
 Worm     1 MKLINCISIALLCTLVDFSSA--------EITVISNLAVVGSPESHVGTPNK------------- 44

  Fly   171 SETGSDLPIY-----IW--YESYPEHIEEGYKGRVSRVSQDSPF------GSASLNLTNIRESDQ 222
                   .:|     :|  .::..|||:..| |..:|:|....|      |...|.:........
 Worm    45 -------TLYANIQNLWCGAQNLGEHIDVEY-GEFTRLSDGKVFKGTVNQGKVYLEIGKASVKVA 101

  Fly   223 GWYECKVVFLNRDPKQHKNGTWFHLDVHAPP--------RFS----VTPEDIIYVNL----GDSI 271
            |.|.|:|..|:   |:..:|   :|.::.||        |.|    ..|..:|....    |:.:
 Worm   102 GRYRCEVRTLD---KEIHSG---NLIIYMPPVLDFPAAVRVSEVLNARPPHVIGAERRGLHGERM 160

  Fly   272 ILNCQADGTPTPEILWYKDANPVDPSPTVGIFNDGTELRISTIRHEDIGEYTCIARN 328
            :|.|.....|.|.:.|.|:..|:..|.::..  ||..|.::::..:.||:|.||..|
 Worm   161 VLECPVLANPEPMVRWEKNGEPLGNSDSIEY--DGNNLILNSLTEDHIGKYRCIGDN 215

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tutlNP_001303307.1 V-set 137..250 CDD:284989 28/127 (22%)
IG_like 137..229 CDD:214653 23/106 (22%)
I-set 253..341 CDD:254352 23/92 (25%)
IGc2 268..331 CDD:197706 18/61 (30%)
I-set 346..437 CDD:254352
Ig 349..437 CDD:299845
Ig 459..530 CDD:299845
IG_like 549..628 CDD:214653
IGc2 551..617 CDD:197706
FN3 633..725 CDD:238020
FN3 786..874 CDD:238020
zig-7NP_491451.2 IGc2 157..216 CDD:197706 18/61 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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