DRSC/TRiP Functional Genomics Resources

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Protein Alignment tutl and Kirrel2

DIOPT Version :9

Sequence 1:NP_001303307.1 Gene:tutl / 46015 FlyBaseID:FBgn0010473 Length:1536 Species:Drosophila melanogaster
Sequence 2:XP_038957463.1 Gene:Kirrel2 / 100359836 RGDID:1308456 Length:711 Species:Rattus norvegicus


Alignment Length:695 Identity:149/695 - (21%)
Similarity:239/695 - (34%) Gaps:189/695 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   103 TPTPTIQVLQFVLVSLLALLAKNAQAHNIPEDAVHITAILGEGVIFNCHVEFPNDHPVPY--VLQ 165
            ||....:.:.|:..::..||..:......|||.|   .:||:.....|.:.       .|  ::|
  Rat     9 TPWVLHKGIPFLSSAIPLLLGSSPHFLQQPEDMV---VLLGQEARLPCALG-------AYRGLVQ 63

  Fly   166 WDKKVSETGSDLPIYIWYESYPEHIEEGYKGRVSRVSQDSPFGSASLNLTNIRESDQGWYECKV- 229
            |.|.....|.:..:..|...:              :|.:|..|...|::..:...|:..|||:. 
  Rat    64 WTKDGLALGGERDLPGWSRYW--------------ISGNSASGQHDLHIKPVELEDEASYECQAS 114

  Fly   230 -VFLNRDPKQHKNGTWFHLDVHAPPRFSVT---PEDIIYVNLGDSIILNCQADGTPTPEILWYKD 290
             ..|...|.|        |.|..||.....   |...:...:..::....:.|..|.||:||::|
  Rat   115 QAGLRSRPAQ--------LHVMVPPEAPQVLGGPSVSLVAGVPGNLTCRSRGDARPAPELLWFRD 171

  Fly   291 ANPVDPSPTVGIFNDGTELRISTIRHEDIG--EYT---------------CIARNGEGQVSHTAR 338
                      ||..|||.....|:|.:..|  |.|               |.||:..........
  Rat   172 ----------GIRLDGTSFHQITLRDKATGTVENTLFLTPSSQDDGATLICRARSQALPTGRDTA 226

  Fly   339 VIIAGGAVIMVPP------TNQTKLEGEKVIFSCEAKAMPGNVTVRWYREGSPVREVAALETRVT 397
            |.::    :..||      ..||..|||||.|.|:|.|.|.....||.:.||||  :.|...|:.
  Rat   227 VTLS----LQYPPMVTLSAEPQTAQEGEKVTFLCQATAQPPVTGYRWAKGGSPV--LGARGPRLE 285

  Fly   398 IRKDGSLIINPIKPDDSGQYLCEVTNGIGDPQSASAYLSVEYPAKVTFTPTVQYLPFRLAGVV-- 460
            :..|.:.:..|:.        |||:|.:|....::|       .:|.:.|.:|..|..::..|  
  Rat   286 VVADATFLTEPVS--------CEVSNAVGSANRSTA-------LEVLYGPILQAKPKPVSVDVGK 335

  Fly   461 ----QCYIKSSPQLQYVTWTKDKRLLEPYQMKDIVVMANG-SLLFTRVNEEHQGQYAC-TPYNAQ 519
                .|..:.:| |..::||:         :....|:::| :|....|..|..|.|.| ......
  Rat   336 DASFSCVWRGNP-LPRISWTR---------LGGSQVLSSGPTLRLPSVALEDAGDYVCRAEPRRT 390

  Fly   520 GTAGASGVMDVLVRKPPAFT-VEPETLYQR------------KVGDSVEMHCD------------ 559
            |..|.:....:.|..||..| :.|...:.|            ...|||....|            
  Rat   391 GVGGGTAQARLTVNAPPVVTALHPAPAFLRGPARLQCVVFASPAPDSVVWSWDEGFLEAGSLGRF 455

  Fly   560 ------ALEAEGTERP-TIKWQRQEGEQLTE-------SQRNRIKISGGNITIENLRREDFGYYQ 610
                  |.|.||.:.| .|......|.|.::       |.|||  :..|.:.|...||:.....:
  Rat   456 LVEAFPAPEVEGGQGPGLISVLHISGTQESDFTTGFNCSARNR--LGEGRVQIHLGRRDLLPTVR 518

  Fly   611 CV---VSNEVATLMAVTQLVI---------------------EGTQPHAPYNITGKATE------ 645
            .|   .|...:..|.:|.:|:                     ||:..|.|...||.:.:      
  Rat   519 LVAGAASAATSLFMVITGVVLCCWRHGSLSKQKNLVRIPGSSEGSSAHGPEEETGSSEDRGPIVH 583

  Fly   646 ---SSITLQWLPGYSGGSEYKQDYTIWFREAGVNDWQTISVTPSG 687
               :.:.|:    .:...|.|.....:::..||:...::...|.|
  Rat   584 TDHNDLVLE----ENEALETKDPTNGYYKVRGVSVSLSLGEAPGG 624

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tutlNP_001303307.1 V-set 137..250 CDD:284989 21/116 (18%)
IG_like 137..229 CDD:214653 17/93 (18%)
I-set 253..341 CDD:254352 23/107 (21%)
IGc2 268..331 CDD:197706 20/79 (25%)
I-set 346..437 CDD:254352 30/96 (31%)
Ig 349..437 CDD:299845 30/93 (32%)
Ig 459..530 CDD:299845 16/78 (21%)
IG_like 549..628 CDD:214653 24/107 (22%)
IGc2 551..617 CDD:197706 22/94 (23%)
FN3 633..725 CDD:238020 11/64 (17%)
FN3 786..874 CDD:238020
Kirrel2XP_038957463.1 IG_like 38..127 CDD:214653 25/120 (21%)
Ig strand A' 40..44 CDD:409353 2/6 (33%)
Ig strand B 48..57 CDD:409353 1/15 (7%)
Ig strand C 62..66 CDD:409353 2/3 (67%)
Ig strand D 75..85 CDD:409353 1/23 (4%)
Ig strand E 88..100 CDD:409353 3/11 (27%)
Ig strand F 107..115 CDD:409353 3/7 (43%)
Ig strand G 117..127 CDD:409353 4/17 (24%)
Ig 133..231 CDD:416386 22/111 (20%)
Ig strand A 134..137 CDD:409353 0/2 (0%)
Ig strand A' 140..144 CDD:409353 1/3 (33%)
Ig strand B 151..158 CDD:409353 0/6 (0%)
Ig strand C 164..169 CDD:409353 3/4 (75%)
Ig strand C' 172..174 CDD:409353 1/1 (100%)
Ig strand D 177..184 CDD:409353 2/6 (33%)
Ig strand E 191..199 CDD:409353 3/7 (43%)
Ig strand F 208..216 CDD:409353 2/7 (29%)
Ig strand G 222..228 CDD:409353 0/5 (0%)
Ig_3 234..303 CDD:404760 27/78 (35%)
Ig strand B 252..256 CDD:409353 2/3 (67%)
Ig strand C 266..270 CDD:409353 1/3 (33%)
Ig strand E 283..286 CDD:409353 1/2 (50%)
Ig strand F 292..301 CDD:409353 2/16 (13%)
Ig strand G 309..312 CDD:409353 0/2 (0%)
Ig 326..403 CDD:416386 17/86 (20%)
Ig strand A' 327..332 CDD:409353 0/4 (0%)
Ig strand B 335..344 CDD:409353 1/8 (13%)
Ig strand C 350..354 CDD:409353 0/3 (0%)
Ig strand C' 357..359 CDD:409353 0/1 (0%)
Ig strand D 362..365 CDD:409353 0/2 (0%)
Ig strand E 366..371 CDD:409353 1/4 (25%)
Ig strand F 379..387 CDD:409353 3/7 (43%)
Ig strand G 393..403 CDD:409353 1/9 (11%)
Ig 405..509 CDD:416386 23/105 (22%)
Ig strand A 406..410 CDD:409353 2/3 (67%)
Ig strand A' 412..415 CDD:409353 0/2 (0%)
Ig strand B 423..430 CDD:409353 0/6 (0%)
Ig strand C 437..442 CDD:409353 2/4 (50%)
Ig strand C' 444..447 CDD:409353 0/2 (0%)
Ig strand D 455..462 CDD:409353 0/6 (0%)
Ig strand E 472..479 CDD:409353 1/6 (17%)
Ig strand F 490..497 CDD:409353 1/6 (17%)
Ig strand G 500..507 CDD:409353 1/6 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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