| Sequence 1: | NP_524865.2 | Gene: | Gel / 46008 | FlyBaseID: | FBgn0010225 | Length: | 798 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_009058.2 | Gene: | VIL1 / 7429 | HGNCID: | 12690 | Length: | 827 | Species: | Homo sapiens |
| Alignment Length: | 753 | Identity: | 266/753 - (35%) |
|---|---|---|---|
| Similarity: | 387/753 - (51%) | Gaps: | 72/753 - (9%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 69 TPGLEIWRIENFEPVIYPKTNYGKFYTGDSFIVLNTIENKKDKKLSWDVHFWLGLETSTDEAGAA 133
Fly 134 AILTVQLDDLLNGGPVQHREVQDHESQLFLSYFKNGIRYEQGGVGTGFKHVETNAQGETRLFQVK 198
Fly 199 GKRNVRVRQVNLSVSSMNTGDCFILDAGSDIYVYVGSQAKRVEKLKAISAANQIRDQDHNGRARV 263
Fly 264 QIVD---DFSTDADKQHFFDVLGSGSADQVPDESTADEDSAFERTDAAAVSLYKVSDASGKLKVD 325
Fly 326 IIGQKPLTQAMLDTRECFILDTGS-GIFVWVGKGATQKEKTDAMAKAQEFLRTKKYPAWTQIHRI 389
Fly 390 VEGSESAPFKQYFDTW----RDAGMSHSRLIRSALGIGSDELLNDDEIDSVVTQLKKSGGRAFGF 450
Fly 451 MPDHGQNVIETITQYVAKPGSDEIVV------STVPFDEKL--PLLGFASYVLTYNY---EANNG 504
Fly 505 DTGSLTYVWHGVKASA-AARKRAFEEGLVGSK---DGLLVQTNQGHEPRHFYKIFKGKLL----- 560
Fly 561 ---TSFTALPVTAQLFRIRGTVESDVHASEVAADSSSLASSDAFVLHSGKSHKIYIWNGLGASAF 622
Fly 623 EKQAAVDRFSDYWDDVELEQVEEGAEPDEFWEELNGEGQY--DRSLGDDGAPLLESRLFHCHLSS 685
Fly 686 GGFLKVEEVAQYEQEDLDSDDIMLLDAGDEIYLWVGYGVSEEENGKLLDTAKLYFNLEPTARSFD 750
Fly 751 TVSIIRVPQGKEPRVFKRMFPNWDDNYWQNQPSYEDMK 788 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Gel | NP_524865.2 | gelsolin_S1_like | 63..176 | CDD:200446 | 52/106 (49%) |
| gelsolin_S2_like | 191..283 | CDD:200445 | 35/94 (37%) | ||
| gelsolin_S3_like | 307..404 | CDD:200448 | 44/97 (45%) | ||
| ADF_gelsolin | 470..558 | CDD:301701 | 30/102 (29%) | ||
| ADF_gelsolin | 569..661 | CDD:301701 | 32/91 (35%) | ||
| gelsolin_S6_like | 675..774 | CDD:200447 | 37/98 (38%) | ||
| VIL1 | NP_009058.2 | Core | 2..734 | 266/753 (35%) | |
| Necessary for homodimerization | 2..126 | 55/111 (50%) | |||
| gelsolin_S1_like | 17..121 | CDD:200446 | 51/105 (49%) | ||
| LPA/PIP2-binding site 1 | 112..119 | 2/6 (33%) | |||
| gelsolin_S2_like | 136..225 | CDD:200445 | 34/88 (39%) | ||
| LPA/PIP2-binding site 2 | 138..146 | 5/7 (71%) | |||
| gelsolin_S3_like | 250..348 | CDD:200448 | 44/97 (45%) | ||
| gelsolin_S4_like | 392..492 | CDD:200449 | 27/103 (26%) | ||
| gelsolin_S5_like | 513..603 | CDD:200444 | 32/92 (35%) | ||
| gelsolin_S6_like | 619..715 | CDD:200447 | 37/97 (38%) | ||
| Headpiece | 735..827 | ||||
| VHP | 793..827 | CDD:280388 | |||
| LPA/PIP2-binding site 3 | 816..824 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165141458 | |
| Domainoid | 1 | 1.000 | 92 | 1.000 | Domainoid score | I7598 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG0443 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 455 | 1.000 | Inparanoid score | I1590 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG55329 | |
| OrthoDB | 1 | 1.010 | - | - | D1376537at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000527 | |
| OrthoInspector | 1 | 1.000 | - | - | otm41645 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100298 | |
| Panther | 1 | 1.100 | - | - | O | PTHR11977 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X232 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 14 | 13.770 | |||||