DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gel and capga

DIOPT Version :9

Sequence 1:	NP_524865.2	Gene:	Gel / 46008	FlyBaseID:	FBgn0010225	Length:	798	Species:	Drosophila melanogaster
Sequence 2:	NP_001275994.1	Gene:	capga / 565410	ZFINID:	ZDB-GENE-060531-6	Length:	345	Species:	Danio rerio

Alignment Length:	353	Identity:	144/353 - (40%)
Similarity:	202/353 - (57%)	Gaps:	17/353 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 RVMHPSFANAGRTPGLEIWRIENFEPVIYPKTNYGKFYTGDSFIVLNTIENKKDKKLSWDVHFWL 121
            |.....|.:..|.|||.:||:|..:.|:...:..|.||.||::|||:  ...||..   |:|.|:
Zfish     5 RAAQSQFTHEVREPGLWVWRVEKMKAVLLDPSQRGIFYNGDAYIVLS--NRGKDGS---DLHMWM 64

  Fly   122 GLETSTDEAGAAAILTVQLDDLLNGGPVQHREVQDHESQLFLSYFKNGIRYEQGGVGTGFKHVET 186
            |.::|.||.||.|:|..|||..|.|.|||||:||..||..|:..|..|:.|::|||.:|||...:
Zfish    65 GEKSSPDEQGACAMLATQLDSFLGGEPVQHRQVQGFESHEFMGLFPKGVSYKEGGVESGFKSARS 129

  Fly   187 NAQGETRLFQVKGKRNVRVRQVNLSVSSMNTGDCFILDAGSDIYVYVGSQAKRVEKLKAISAANQ 251
            .......|:|||||:|:|.|:|..|..|.|.|||||||.|.:|.|::||:|...|:.|....|..
Zfish   130 RIDPVKYLYQVKGKKNIRAREVEFSWGSFNKGDCFILDLGENIVVWIGSKANMFERQKVREIAML 194

  Fly   252 IRDQDHNGRARVQIVDDFSTDADKQHFFDVLGSGSADQVPDESTADEDSAFERTDAAAVSLYKVS 316
            |||.:.||:|.:..|.:.....:.     |...|....:.|.|| :|||..:.|::|  ||||||
Zfish   195 IRDTERNGKAHIIDVREGEEPVEM-----VKALGPVPALKDSST-EEDSEADITNSA--SLYKVS 251

  Fly   317 DASGKLKVDIIGQK-PLTQAMLDTRECFILDTGSG--IFVWVGKGATQKEKTDAMAKAQEFLRTK 378
            :|:|::.:..:..| |..|.:|:..:|||||.||.  |:||.|.||..:||..|:..|.||:...
Zfish   252 NATGQMTLTKLCDKGPFGQELLEKDDCFILDNGSNGKIYVWKGNGANAEEKRVALKVADEFITEM 316

  Fly   379 KYPAW-TQIHRIVEGSESAPFKQYFDTW 405
            .||.. ||:..:.:|.||..|||:|.:|
Zfish   317 NYPRMRTQVEILPQGRESVLFKQFFKSW 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gel	NP_524865.2	gelsolin_S1_like	63..176	CDD:200446	48/112 (43%)
		gelsolin_S2_like	191..283	CDD:200445	37/91 (41%)
		gelsolin_S3_like	307..404	CDD:200448	43/100 (43%)
		ADF_gelsolin	470..558	CDD:301701
		ADF_gelsolin	569..661	CDD:301701
		gelsolin_S6_like	675..774	CDD:200447
capga	NP_001275994.1	gelsolin_S1_like	16..119	CDD:200446	47/107 (44%)
		gelsolin_S2_like	137..223	CDD:200445	37/90 (41%)
		gelsolin_S3_like	245..343	CDD:200448	43/99 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574418
Domainoid	1	1.000	70	1.000	Domainoid score	I9475
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1376537at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850