Protein Alignment Gel and vill

DIOPT Version :10

• Sequence 1: NP_524865.2
• Gene: Gel / 46008
• FlyBaseID: FBgn0010225
• Length: 798
• Species: Drosophila melanogaster
• Sequence 2: XP_021325987.1
• Gene: vill / 555361
• ZFINID: ZDB-GENE-081222-1
• Length: 910
• Species: Danio rerio
• Alignment Length: 776
• Identity: 282/776 - (36%)
• Similarity: 400/776 - (51%)
• Gaps: 77/776 - (9%)

  Fly    60 HPSFANAGRTPGLEIWRIENFEPVIYPKTNYGKFYTGDSFIVLNTIENKKDKKLSWDVHFWLGLE 124
            |..|.|..|.|||:||.|...:.|..|:..:|.|:.||.:|:||...|...   |.|:|:|:|..
Zfish    65 HDLFKNIQRKPGLQIWTINKMQMVAVPEQAFGNFFEGDCYIILNVSNNPAQ---SIDIHYWIGNS 126

  Fly   125 TSTDEAGAAAILTVQLDDLLNGGPVQHREVQDHESQLFLSYFKNGIRYEQGGVGTGFKHVETNAQ 189
            :|.||.|||||...|||:...|.|||:||||.|||..|.||||||:.|::|||.:||.|||||..
Zfish   127 SSQDEQGAAAIYVTQLDENFGGSPVQYREVQGHESVKFKSYFKNGLIYKKGGVASGFTHVETNVY 191

  Fly   190 GETRLFQVKGKRNVRVRQVNLSVSSMNTGDCFILDAGSDIYVYVGSQAKRVEKLKAISAANQIRD 254
            ...||..|||.::|..|:|.:|.:|.|.||.|:||.|..|..:.|.|:.|.|||||:..|..|||
Zfish   192 NIQRLLHVKGTKHVTGREVEVSWNSFNLGDVFLLDLGKAIIQWNGPQSNRQEKLKAVMLAQDIRD 256

  Fly   255 QDHNGRARVQIVDDFSTDADKQHFFDVLGSGSADQVPDESTADEDSAFERTDAAAVSLYKVSDAS 319
            ::..|||::.:::....:|..: ...|:.|....::.....|..|....:...:.|.||:|||||
Zfish   257 RERGGRAQIGVIEGAQEEASPE-LMKVMVSVLGQRIGQMKEAIPDDKPGQNQISNVKLYQVSDAS 320

  Fly   320 GKLKVDIIGQKPLTQAMLDTRECFILDT-GSGIFVWVGKGATQKEKTDAMAKAQEFLRTKKYPAW 383
            |:|.|..:...||||.:|.:.:|:|||. |:.|.||.||||:.:|:..||.:|..|::.|.|||.
Zfish   321 GQLLVQEVAVSPLTQDLLCSSDCYILDQGGTSIMVWKGKGASNEERRSAMGRAVGFIKAKNYPAS 385

  Fly   384 TQIHRIVEGSESAPFKQYFDTWRDAGMSHSRLIRSALGIGSDELLND-DEIDSVVTQLKKSGGRA 447
            |::..:.||.|||.|||.|.:|.:.|.:.        |:|....:.. .::|.|          .
Zfish   386 TKVEVMSEGGESAMFKQLFKSWTEKGQTQ--------GLGKTHSVGKIAKVDQV----------K 432

  Fly   448 FGFMPDHGQNVIETITQYVAKPGSDEIVVSTVPFDEKLPL-----------LGFASYVLTYNYEA 501
            |..|..|.|..: ...:.:....|.::.|..:   |.|.|           .|...|::.|.|..
Zfish   433 FDVMELHAQPKL-AAQERMVDDASGQVQVWRI---ENLELKEVDRSTYGQFYGGDCYLVLYTYNR 493

  Fly   502 NNGDTGSLTYVWHGVKAS----AAARKRAFEEGLVGSKDGLLVQTN--QGHEPRHFYKIFKGKLL 560
            .| ....:.|:|.|..|:    .|:..:|.  .|....:|...|..  .|.|||||..||||:|:
Zfish   494 AN-KPQYILYIWQGRHATQDEVTASAYQAV--NLDNKYNGAPTQVRVVMGKEPRHFMAIFKGRLI 555

  Fly   561 -------TSFTALP-VTAQLFRIRGTVESDVHASEVAADSSSLASSDAFVLHSGKSHKIYIWNGL 617
                   .|....| ..|:||::|||.|.:..|:||.|.:|||.::|.|:|.:.::  :::|.|.
Zfish   556 IFEGGTGRSGVVNPDPAARLFQVRGTHELNTKATEVPARASSLNTNDVFLLKTYQT--VFLWYGK 618

  Fly   618 GASAFEKQ---AAVDRFSDYWDDVELEQVEEGAEPDEFWEELNGEGQY--DRSLGDDGAPLLESR 677
            |.|..|::   |..|..|..    :.:.|.||.||..||..|.|:..|  |:.| ::...|.|.|
Zfish   619 GCSGDEREMGKAVADLLSGQ----DKQTVMEGQEPAAFWVPLGGKAPYASDKRL-EEEVSLHEPR 678

  Fly   678 LFHCHLSSGGFLKVEEVAQYEQEDLDSDDIMLLDAGDEIYLWVGYGVSEEENGKLLDTAKLYFNL 742
            ||.|...:|.|| :.|||.:.|:|||.||:||||..|||:||:|...::.|..:...:|..|...
Zfish   679 LFECSNQTGRFL-MTEVADFTQDDLDEDDVMLLDTWDEIFLWIGNSANQYEIQESSSSAVEYLKT 742

  Fly   743 EPTARSFDTVSIIRVPQGKEPRVFKRMFPNWDDNYWQNQPSYEDMK-------QLVIDANN 796
            .|..|...| .|..|.||.||..|...|..||.:.|....|||:||       |:.:..||
Zfish   743 HPAGRDAGT-PITTVKQGYEPPTFTGWFNAWDAHKWSGGLSYEEMKSKLGDVSQITVSLNN 802

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gel	NP_524865.2	gelsolin_S1_like	63..176	CDD:200446	54/112 (48%)
		gelsolin_S2_like	191..283	CDD:200445	35/91 (38%)
		gelsolin_S3_like	307..404	CDD:200448	47/97 (48%)
		ADF_gelsolin	470..558	CDD:472830	28/104 (27%)
		ADF_gelsolin	569..661	CDD:472830	34/94 (36%)
		gelsolin_S6_like	675..774	CDD:200447	41/98 (42%)
vill	XP_021325987.1	gelsolin_S1_like	68..178	CDD:200446	54/112 (48%)
		gelsolin_S2_like	194..282	CDD:200445	34/88 (39%)
		gelsolin_S3_like	309..406	CDD:200448	47/96 (49%)
		gelsolin_S4_like	450..550	CDD:200449	25/105 (24%)
		gelsolin_S5_like	571..661	CDD:200444	34/95 (36%)
		gelsolin_S6_like	676..773	CDD:200447	41/98 (42%)
		VHP	875..910	CDD:460493