Protein Alignment Gel and gsn

DIOPT Version :10

• Sequence 1: NP_524865.2
• Gene: Gel / 46008
• FlyBaseID: FBgn0010225
• Length: 798
• Species: Drosophila melanogaster
• Sequence 2: XP_031746326.1
• Gene: gsn / 549610
• XenbaseID: XB-GENE-489535
• Length: 750
• Species: Xenopus tropicalis
• Alignment Length: 768
• Identity: 275/768 - (35%)
• Similarity: 411/768 - (53%)
• Gaps: 88/768 - (11%)

  Fly    58 VMHPSFANAGRTPGLEIWRIENFEPVIYPKTNYGKFYTGDSFIVLNTIENKKDKKLSWDVHFWLG 122
            |.||.|..||:.|||::||:|.|:.|..|:..||.|:|||:::||:||:.:.. .|.:|:|:|||
 Frog    20 VDHPEFEKAGKAPGLQVWRVEKFDLVAVPQNQYGSFFTGDAYLVLSTIKTRSG-NLQYDLHYWLG 83

  Fly   123 LETSTDEAGAAAILTVQLDDLLNGGPVQHREVQDHESQLFLSYFKNGIRYEQGGVGTGFKHVETN 187
            .|.:.||:|:|||.|||:||.|.|.|:|:||||.:||..||.|||.||:|:.|||.:||.||..|
 Frog    84 DECTQDESGSAAIFTVQMDDHLGGQPIQNREVQGYESSTFLGYFKPGIKYKAGGVASGFTHVVPN 148

  Fly   188 AQGETRLFQVKGKRNVRVRQVNLSVSSMNTGDCFILDAGSDIYVYVGSQAKRVEKLKAISAANQI 252
            .....||.||||:|.||..:|.::..|.|.|||||||.|::||.:.||::.:.|||:|.:.|..|
 Frog   149 EVDIKRLLQVKGRRVVRATEVPVNWDSFNQGDCFILDLGNEIYQWFGSKSNQFEKLRATAVAKGI 213

  Fly   253 RDQDHNGRARVQIVDDFSTDADKQHFFDVLGSGSADQVPD--ESTADEDSAFERTDAAAVSLYKV 315
            ||.:.|||:::.:|::   ..:::...:|||     |.||  |..||:..| :.::.....||||
 Frog   214 RDTERNGRSKLYVVEE---GMEREKMIEVLG-----QKPDLPEGPADDIKA-DASNRKLAKLYKV 269

  Fly   316 SDASGKLKVDIIG-QKPLTQAMLDTRECFILDTGSG--IFVWVGKGATQKEKTDAMAKAQEFLRT 377
            ||..|.:.|.::. |.|.|||.|::.:||:||.||.  ||||.|:.|..:||..|:..|.||:..
 Frog   270 SDGKGAMTVSLVADQNPFTQAALNSDDCFVLDHGSDGKIFVWKGRNANMEEKKAALKTATEFISK 334

  Fly   378 KKYPAWTQIHRIVEGSESAPFKQYFDTWRDAGMSHSRLIRSALGIG--SDELLNDDEIDSVVTQL 440
            ..||..||:..:.|..|:..|||:|..|:|      :.....:|:.  ...:...:.:...|:.|
 Frog   335 MGYPKQTQVQVLPENGETPLFKQFFKNWKD------KEATEGMGVAYVPHHIAKIENVPFDVSGL 393

  Fly   441 KKSGGRAFGFMPDHGQNVIETITQYVAKPGSDEIVVSTVPFDEKLPL--------LGFASYVLTY 497
            .:|...|    ..||          :...||.:..:..:...:|:|:        .|..||::.|
 Frog   394 HESPAMA----AQHG----------MVDDGSGQKQIWRIEDCKKVPVSKSLYGQFYGGDSYIILY 444

  Fly   498 NYEANNGDTGSLTYVWHG-------VKASAAARKRAFEE----GLVGSKDGLLVQTNQGHEPRHF 551
            ||: :.|..|.:.|.|.|       |.|||....:..||    .:.|::.  .|:..||.||.|.
 Frog   445 NYK-HGGKQGQIIYTWQGDESSKDEVTASAILSAQLDEELGGTPVQGARS--QVRVVQGKEPAHL 506

  Fly   552 YKIFKGKLL------TS---FTALPVTAQLFRIRGTVESDVHASEVAADSSSLASSDAFVLHSGK 607
            ..:|.||.:      ||   ........:||::|.:......|.||.:.:|:|.|:|||||.:..
 Frog   507 MSLFGGKPMIVNKGGTSREGGQTKDADVRLFQVRASSSGFSRAVEVDSTASNLNSNDAFVLKTPS 571

  Fly   608 SHKIYIWNGLGASAFEKQAAVDRFSDYWDDVELEQVEEGAEPDEFWEELNGEGQYDRSLGDDGAP 672
            :  .|.|.|.|::..||:.|.:..:..  .|...::.||.|.|:||..|.|:..|..|     |.
 Frog   572 A--AYQWVGQGSTDAEKKGAQELLAVL--GVSASEILEGQETDDFWAALGGKADYRTS-----AR 627

  Fly   673 LLES------RLFHCHLSSGGFLKVEEV-AQYEQEDLDSDDIMLLDAGDEIYLWVGYGVSEEENG 730
            |.:.      |||.|...:|.|: :||| .:..|:||.:||:||||..|::::|||....|:|..
 Frog   628 LKDKLNTHPPRLFACSNKTGRFI-IEEVPGEISQDDLATDDVMLLDTWDQVFVWVGKEAQEDEKK 691

  Fly   731 KLLDTAKLYFNLEPTARSFDT-VSIIRVPQGKEPRVFKRMFPNWDDNYWQNQP 782
            :.:.:|..|...:|..|...| |:||:  ||.||..|...|..|:.:||...|
 Frog   692 EAIASAYKYIESDPANRDKRTPVAIIK--QGFEPPTFTGWFLGWETDYWDISP 742

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gel	NP_524865.2	gelsolin_S1_like	63..176	CDD:200446	58/112 (52%)
		gelsolin_S2_like	191..283	CDD:200445	37/91 (41%)
		gelsolin_S3_like	307..404	CDD:200448	42/99 (42%)
		ADF_gelsolin	470..558	CDD:472830	29/106 (27%)
		ADF_gelsolin	569..661	CDD:472830	30/91 (33%)
		gelsolin_S6_like	675..774	CDD:200447	38/106 (36%)
gsn	XP_031746326.1	gelsolin_S1_like	25..137	CDD:200446	58/112 (52%)
		gelsolin_S2_like	153..241	CDD:200445	37/90 (41%)
		gelsolin_S3_like	261..361	CDD:200448	42/99 (42%)
		gelsolin_S4_like	405..510	CDD:200449	28/107 (26%)
		gelsolin_S5_like	534..621	CDD:200444	30/90 (33%)
		gelsolin_S6_like	636..734	CDD:200447	38/100 (38%)