Protein Alignment Gel and vill

DIOPT Version :10

• Sequence 1: NP_524865.2
• Gene: Gel / 46008
• FlyBaseID: FBgn0010225
• Length: 798
• Species: Drosophila melanogaster
• Sequence 2: NP_001005657.1
• Gene: vill / 448145
• XenbaseID: XB-GENE-945607
• Length: 876
• Species: Xenopus tropicalis
• Alignment Length: 792
• Identity: 275/792 - (34%)
• Similarity: 395/792 - (49%)
• Gaps: 105/792 - (13%)

  Fly    59 MHPSFANAGRTPGLEIWRIENFEPVIYPKTNYGKFYTGDSFIVLNTIENKKDKK-LSWDVHFWLG 122
            |..:..|..|.|||:||.:|..:.|..|:..||.|:.||.:|:|   .||:... |..|:|:|:|
 Frog     1 MTQNLENMCRKPGLQIWSMEKMKLVPIPEKAYGSFFEGDCYILL---YNKQTPNGLISDIHYWIG 62

  Fly   123 LETSTDEAGAAAILTVQLDDLLNGGPVQHREVQDHESQLFLSYFKNGIRYEQGGVGTGFKHVETN 187
            .::|.||.|:||....|:|.||.|||:||||||.|||..|.||||||:.|::|||.:||||||||
 Frog    63 KDSSQDEQGSAAFYATQIDGLLGGGPIQHREVQGHESATFKSYFKNGVIYKKGGVSSGFKHVETN 127

  Fly   188 AQGETRLFQVKGKRNVRVRQVNLSVSSMNTGDCFILDAGSDIYVYVGSQAKRVEKLKAISAANQI 252
            .....||..||||::|...:|.:|.:|.|.||.|:||.|..|..:.|.::.:.|:::|.|.|..|
 Frog   128 MYNIRRLLHVKGKKHVTATEVAMSWNSFNKGDVFLLDLGKVIIQWNGPESNKSERIRACSLAQSI 192

  Fly   253 RDQDHNGRARVQIVDDFSTDAD-KQHFFDVLGSGSA---DQVPDESTADEDSAFERTDAAAVSLY 313
            ||.:..|||::.::|:.....| .|....|||:.:.   |.||||. |||.      ..|.|.||
 Frog   193 RDDERGGRAQIGVIDNEQDSPDLMQIMVAVLGARTGELKDSVPDEK-ADEQ------QKANVRLY 250

  Fly   314 KVSDASGKLKVDIIGQKPLTQAMLDTRECFILDTGS-GIFVWVGKGATQKEKTDAMAKAQEFLRT 377
            .|.:....|.|..:..|||||.:|...:|.|||.|. .|:||.||.::.:||:.|.::|..|::.
 Frog   251 HVFEKDANLVVQELATKPLTQDLLQHEDCHILDQGGVKIYVWRGKNSSPEEKSAAFSRAVGFIQA 315

  Fly   378 KKYPAWTQIHRIVEGSESAPFKQYFDTWRDAGMSHSRLIRSALGIGSDELLNDDEIDSVVTQLKK 442
            |.||..|.:..:.:|:|||.|||.|..|:|.|.:..  :.....:|....:...:.|
 Frog   316 KGYPPTTNVEVVNDGAESAMFKQLFQNWKDVGETQG--LGKTFSVGKIAKVEQTKFD-------- 370

  Fly   443 SGGRAFGFMPDHGQNVIETITQYVAKP-----------GSDEIVVSTVPFDEKLPL--------- 487
                               :.|..|:|           .|..:.|..:   |||.|
 Frog   371 -------------------VNQLYARPELAAEQRMVDDASGNVEVWRI---EKLELAEVEPRTYG 413

  Fly   488 --LGFASYVLTYNYEANNGDTGSLTYVWHGVKASA-AARKRAFEEGLVGSK---DGLLVQTNQGH 546
              .|...|::.|.| ..:|....|.|:|.|..||. .....||:...:..|   ..:.::...|.
 Frog   414 QFYGGDCYLILYTY-MKSGRPNYLLYMWLGRHASQDEITACAFQAVQLDKKYHDQPVQIRVTMGK 477

  Fly   547 EPRHFYKIFKGKLL-----TSFTAL-----PVTAQLFRIRGTVESDVHASEVAADSSSLASSDAF 601
            ||||...:||||::     ||...:     |:  :||:::||.|.:..|:||.|.:|||.|:|.|
 Frog   478 EPRHLQAMFKGKMIIYEGGTSRLGVHEPEAPI--KLFQVKGTNEYNTKATEVPARASSLNSNDVF 540

  Fly   602 VLHSGKSHKIYIWNGLGASAFEKQAAVDRFSDYWDDVELEQVEEGAEPDEFWEELNGEGQY--DR 664
            ||.:  ....|:|.|.|.|..|::.| ...::.....:.:.:.||.||.|||..|.|:..|  |:
 Frog   541 VLKT--ESMCYLWCGKGCSGDEREMA-KTVANIISKQDKQTILEGQEPAEFWVALGGKAPYASDK 602

  Fly   665 SLGDDGAPLLESRLFHCHLSSGGFLKVEEVAQYEQEDLDSDDIMLLDAGDEIYLWVGYGVSEEEN 729
            .. .:.|.....|||.|...:|.|: :.||..:.|.|||.||:||||..:||:||||...::.|.
 Frog   603 RF-QEQAVQYSPRLFECSNQTGRFV-MTEVVDFCQSDLDEDDVMLLDTWEEIFLWVGKSANDYEK 665

  Fly   730 GKLLDTAKLYFNLEPTARSFDTVSIIRVPQGKEPRVFKRMFPNWDDNYWQNQPSYEDMK------ 788
            .:.:..::.|....|..|...| .||.|.||.||..|...|..||.:.|.:..||||||
 Frog   666 TESVKASQEYLRAHPAGRDLAT-PIILVKQGHEPPTFTGWFNAWDSHKWSSDLSYEDMKKTLGDV 729

  Fly   789 ----QLVIDANN 796
                |:.:|..|
 Frog   730 SAISQISVDLQN 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gel	NP_524865.2	gelsolin_S1_like	63..176	CDD:200446	54/113 (48%)
		gelsolin_S2_like	191..283	CDD:200445	33/92 (36%)
		gelsolin_S3_like	307..404	CDD:200448	40/97 (41%)
		ADF_gelsolin	470..558	CDD:472830	27/102 (26%)
		ADF_gelsolin	569..661	CDD:472830	33/91 (36%)
		gelsolin_S6_like	675..774	CDD:200447	38/98 (39%)
vill	NP_001005657.1	gelsolin_S1_like	5..116	CDD:200446	54/113 (48%)
		gelsolin_S2_like	133..224	CDD:200445	33/90 (37%)
		gelsolin_S3_like	244..342	CDD:200448	40/97 (41%)
		gelsolin_S4_like	386..486	CDD:200449	25/103 (24%)
		gelsolin_S5_like	507..597	CDD:200444	34/94 (36%)
		gelsolin_S6_like	613..709	CDD:200447	38/97 (39%)
		VHP	841..876	CDD:460493