Protein Alignment Gel and Svil

DIOPT Version :10

• Sequence 1: NP_524865.2
• Gene: Gel / 46008
• FlyBaseID: FBgn0010225
• Length: 798
• Species: Drosophila melanogaster
• Sequence 2: NP_001286919.1
• Gene: Svil / 38306
• FlyBaseID: FBgn0266696
• Length: 4526
• Species: Drosophila melanogaster
• Alignment Length: 740
• Identity: 176/740 - (23%)
• Similarity: 284/740 - (38%)
• Gaps: 196/740 - (26%)

  Fly   194 LFQVKGKRNVRVRQVNLSVSSMNTGDCFILDAGSDIYVYVGSQAKRVE--KLKAISAANQIRDQD 256
            |..|||:.:|:.|.|....:|:|.||||||.|||.::.||||.|..:|  :.|.|.|| .:.::|
  Fly  3736 LLHVKGRTHVQTRLVEPVHTSLNRGDCFILVAGSQLFRYVGSFANVIEISRSKKICAA-IVENKD 3799

  Fly   257 HNGRARVQIV---DDFSTDADKQHFFDVLGSGSADQ--VPDESTADEDSAFERTDAAAVSLYKVS 316
            ....|..:::   ..:..:...:.|:.:||....||  :.:...||||..||.:......:|:..
  Fly  3800 LGCTATQEVILTDGKYLKERQWRQFWQLLGKKEDDQSDIAECGHADEDDVFESSLIETNKIYEYQ 3864

  Fly   317 DAS--------GKL-KVDIIGQKPLTQAMLDTRECFILDTGSGIFVWVGKGATQKEKTDAMAKAQ 372
            |.:        |.: |||          |||||:..:.|.||.::||.||.|....|..||..||
  Fly  3865 DEALIPLEKFWGCIPKVD----------MLDTRKVLVFDFGSELYVWNGKNAPSDAKRAAMRLAQ 3919

  Fly   373 E-------------FLRTKKY-------------------PAWTQIHRIVEGSESAPFKQYFDTW 405
            |             :|....|                   |.|..:.:|.:..|:..||:.|..|
  Fly  3920 EHFGAENSADYADCYLNPLNYVAIVGRRENTKYAKRCAQRPEWCVLGKITQNMETVLFKEKFSDW 3984

  Fly   406 ---------RDAGMSHSRLIRSALGIGSDELLNDDEIDSVVTQLKKSGGRAFGFMPDHGQNVIET 461
                     :|...:...::|:..|....:.....|.:.|:.|.....|   .|..|     .:|
  Fly  3985 PEIEREDLEKDYLSNGVHMVRALNGTALHKGEPYQEPNLVLEQANLGRG---NFYYD-----TDT 4041

  Fly   462 ITQY-VAKPGSDEIVVSTVPF------DEKLPLLGFASYVLTYNYE------------ANNGDTG 507
            :..: |....:|:..:....|      |:........||::.:.|:            :|....|
  Fly  4042 MRHFDVITKSTDKWQIHEFNFDAANNRDDYGHFYSAESYIVRWIYQISVTVRELSGKVSNRSTVG 4106

  Fly   508 ---SLTYVWHGVKASA----AARKRAFEEGLVGSKDGLLVQTNQGHEPRHFYKIF---------K 556
               .:.:.|.|..:||    ||.....|   :..:.|..::.:||.|...|.::|         |
  Fly  4107 RDRCVYFTWQGQDSSANEKGAAALLTVE---LDKEKGAQMRVSQGDECTAFVRLFRQMWQHRGRK 4168

  Fly   557 GKLLTSFTALPVTAQLFRIRGTVESDVHASEVAADSSSLASSDAFVLHSGKSHKIYIWNGLGASA 621
            .:.|...:..    :|::::|.|..:....||...||.|.|..:.:|..|....:.:|:|..::.
  Fly  4169 EQCLERHSEW----RLYQLQGNVSEETIIKEVVCQSSHLRSRSSMLLIHGSQGNVIVWHGSKSAP 4229

  Fly   622 FEKQAAV------------DRFSDYWDDVELEQVEEGAEPDEFWEELNGEGQYDRSLG-----DD 669
            ..:..||            |.||.  :...|.:||||::.|          |..::||     ::
  Fly  4230 HTRNVAVGVAQDLIKTVPKDLFSA--ETANLTEVEEGSDDD----------QCKKALGLKDERNE 4282

  Fly   670 GAPLLES--------RLFHCHLSSGGFLKVEEVAQYEQEDLDS--------------DDIMLLDA 712
            ...||:|        |:|:...:.|.|..:|.......:||.|              ..|.|||.
  Fly  4283 YGSLLKSTKSFDYQIRIFNFSSTQGVFKALELSDPLRCQDLHSPYPFSQSQLYNARQPTIFLLDD 4347

  Fly   713 GDEIYLWVGY----------------------GVSE--EENGKLLDTAKLYFNL---EPTARSFD 750
            |||::||:|:                      ||:.  .|....|:||..|:..   |.....|.
  Fly  4348 GDELWLWMGWWPLEDVKINTDERSSPTNENRAGVNRWISERRAALETAVDYWRAKHGENENEPFH 4412

  Fly   751 TVSIIRVPQGKEPRVFKRMFPNWDD 775
            .:....|..|.||..||.:||:|.:
  Fly  4413 GIKGQVVWAGLEPLAFKALFPDWTE 4437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gel	NP_524865.2	gelsolin_S1_like	63..176	CDD:200446
		gelsolin_S2_like	191..283	CDD:200445	31/93 (33%)
		gelsolin_S3_like	307..404	CDD:200448	34/137 (25%)
		ADF_gelsolin	470..558	CDD:472830	22/121 (18%)
		ADF_gelsolin	569..661	CDD:472830	24/103 (23%)
		gelsolin_S6_like	675..774	CDD:200447	36/147 (24%)
Svil	NP_001286919.1	gelsolin_S2_like	3733..3825	CDD:200445	30/89 (34%)
		gelsolin_like	3859..3965	CDD:200436	29/115 (25%)
		ADF_gelsolin	<4069..4158	CDD:472830	18/91 (20%)
		gelsolin_S5_like	4176..4279	CDD:200444	27/118 (23%)
		ADF_gelsolin	4328..4435	CDD:472830	27/106 (25%)
		VHP	4491..4526	CDD:460493