Protein Alignment Gel and gsna

DIOPT Version :10

• Sequence 1: NP_524865.2
• Gene: Gel / 46008
• FlyBaseID: FBgn0010225
• Length: 798
• Species: Drosophila melanogaster
• Sequence 2: XP_021324427.2
• Gene: gsna / 321099
• ZFINID: ZDB-GENE-030131-9653
• Length: 738
• Species: Danio rerio
• Alignment Length: 773
• Identity: 287/773 - (37%)
• Similarity: 418/773 - (54%)
• Gaps: 74/773 - (9%)

  Fly    58 VMHPSFANAGRTPGLEIWRIENFEPVIYPKTNYGKFYTGDSFIVLNTIENKKDKKLSWDVHFWLG 122
            |.||.|..||:.|||::||||.|:.|..|:..||.|||||:::||.||: :....|.:|:|||||
Zfish     2 VYHPEFERAGKEPGLQVWRIEKFDLVAVPENLYGGFYTGDAYLVLKTIK-QTSGNLQYDLHFWLG 65

  Fly   123 LETSTDEAGAAAILTVQLDDLLNGGPVQHREVQDHESQLFLSYFKNGIRYEQGGVGTGFKHVETN 187
            ...:.||:|:|||.|||:||.|.|.|:|:||||.|||:.||.|||.|::|.||||.:|||||.||
Zfish    66 DYCTQDESGSAAIFTVQMDDYLGGKPIQYREVQGHESKSFLGYFKKGLQYMQGGVASGFKHVVTN 130

  Fly   188 AQGETRLFQVKGKRNVRVRQVNLSVSSMNTGDCFILDAGSDIYVYVGSQAKRVEKLKAISAANQI 252
            .....|:.||||:|.||..:|.:|..|.|.|||||||.|::||.:.||::.|.|||||...|..|
Zfish   131 EVVMQRVLQVKGRRVVRATEVPVSWDSFNQGDCFILDLGNEIYQWCGSKSNRFEKLKATQLAKGI 195

  Fly   253 RDQDHNGRARVQIVDDFSTDADKQHFFDVLGSGSADQVPD--ESTADEDSAFERTDAAAVSLYKV 315
            ||.:.:|||||.:.|:   ..:::...:|||     :.||  |..:|:..| :.::.....||||
Zfish   196 RDNERSGRARVYVCDE---GVEREKMLEVLG-----EKPDLPEGASDDVKA-DASNRKMAKLYKV 251

  Fly   316 SDASGKLKVDII-GQKPLTQAMLDTRECFILDTGSG--IFVWVGKGATQKEKTDAMAKAQEFLRT 377
            |||||.:.:.:: .:.|.||:.|::.:|||||.||.  ||||.||.|..:|:..||..|.||::.
Zfish   252 SDASGDMAIALVAAENPFTQSALESSDCFILDHGSDGKIFVWKGKDANMEERKAAMKAADEFIKK 316

  Fly   378 KKYPAWTQIHRIVEGSESAPFKQYFDTWRDAGMSHSRLIRSALGIG--SDELLNDDEIDSVVTQL 440
            ..||..||:..:.|..|:..|||:|..|||...:      ..:|:.  |:.:...:::....:.|
Zfish   317 MGYPKHTQVQILPEMGETPLFKQFFKNWRDVDQT------EGMGVAYVSNSIAKIEKVPFDASTL 375

  Fly   441 KKSGGRA--FGFMPD-HGQNVIETITQYVAKPGSDEIVVSTVPFDEKLPLLGFASYVLTYNYEAN 502
            ..|...|  .|.:.. :|:..|..|      .|||::.|....:.:   ..|..||::.|:|. :
Zfish   376 HDSPAMAAQHGMIDSGNGEKQIWRI------EGSDKVPVDPSTYGQ---FYGGDSYIILYSYR-H 430

  Fly   503 NGDTGSLTYVWHG-------VKASAAARKRAFEE------GLVGSKDGLLVQTNQGHEPRHFYKI 554
            .|..|.:.|:|.|       :.|||....:..:|      .:.|:.....|:..||.||.|...:
Zfish   431 GGRQGHIIYIWQGADSTQDEIGASAILGAQLDDELGGGPVQMAGAPLTTQVRVVQGKEPAHLMSL 495

  Fly   555 FKGKLLT----------SFTALPVTAQLFRIRGTVESDVHASEVAADSSSLASSDAFVLHSGKSH 609
            |.|:.:.          ..|| |...:||::|........|.|:.|.||:|.|:|||||.:..:.
Zfish   496 FGGQPMVVHKGGTSREGGQTA-PAETRLFQVRSNSAGCTRAVEIDAVSSNLNSNDAFVLVTPAAS 559

  Fly   610 KIYIWNGLGASAFEKQAAVDRFSDYWDDVELEQVEEGAEPDEFWEELNGEGQYDRS--LGD--DG 670
              :||.|.|||..||:.|.......  .|...::.||.|...||:.|.|:..|..|  |.|  :.
Zfish   560 --FIWVGQGASDIEKRGAQQLCGIL--GVSPSELSEGGEDGGFWDALGGKAAYRTSSRLKDKMNA 620

  Fly   671 APLLESRLFHCHLSSGGFLKVEEV-AQYEQEDLDSDDIMLLDAGDEIYLWVGYGVSEEENGKLLD 734
            .|   .|||.|...:|.|: :||| .:..||||.:||:|:||..|::::|:|....:||..:.:.
Zfish   621 HP---PRLFACSNKTGRFI-IEEVPGEMTQEDLATDDVMILDTWDQVFVWIGNEAHDEEKMEAMT 681

  Fly   735 TAKLYFNLEPTARSFDTVSIIRVPQGKEPRVFKRMFPNWDDNYWQNQPSYEDMKQLVI 792
            :|..|...:|..|...| :|:::.||.||..|...|..||.:||...|....|.:|.|
Zfish   682 SAAQYIQTDPANRDPRT-AIVKIKQGFEPPTFTGWFLGWDHDYWSTDPLERAMAELEI 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gel	NP_524865.2	gelsolin_S1_like	63..176	CDD:200446	61/112 (54%)
		gelsolin_S2_like	191..283	CDD:200445	41/91 (45%)
		gelsolin_S3_like	307..404	CDD:200448	43/99 (43%)
		ADF_gelsolin	470..558	CDD:472830	26/100 (26%)
		ADF_gelsolin	569..661	CDD:472830	32/91 (35%)
		gelsolin_S6_like	675..774	CDD:200447	35/99 (35%)
gsna	XP_021324427.2	None