Protein Alignment Gel and svila

DIOPT Version :10

• Sequence 1: NP_524865.2
• Gene: Gel / 46008
• FlyBaseID: FBgn0010225
• Length: 798
• Species: Drosophila melanogaster
• Sequence 2: NP_001417872.2
• Gene: svila / 30112
• ZFINID: ZDB-GENE-990706-5
• Length: 2264
• Species: Danio rerio
• Alignment Length: 1080
• Identity: 234/1080 - (21%)
• Similarity: 370/1080 - (34%)
• Gaps: 377/1080 - (34%)

  Fly    11 VLSSLLVFLALSSSLCSAGTLNARPAFPVQSGEIQPSGQ--------NSKQAARRVMHPSFANAG 67
            |.||.|  |..|..|.....|......|||..|..|..:        .|:|..|..|........
Zfish  1172 VFSSSL--LCASEPLDQIANLPKATLLPVQVDERHPWRRKKMGNEVVESQQLERVEMSIQERKQL 1234

  Fly    68 RTPGLEIWRIENF---------------------------EPVIYPKTNYGKFYTGDSFIVLNT- 104
            .|...|.|:.:.:                           .||:.|.::..|          ||
Zfish  1235 ITSQEEAWKAKGYGAANDSTQFTVAGRMVKKGLAAPSVLTNPVLSPLSSKNK----------NTS 1289

  Fly   105 ---------IENKKDKKLSWDVHF-----WL--------GLETST---DEAGAAAILTV------ 138
                     ||.|::.||..|:..     :|        ||:.:|   .|.....::|:
Zfish  1290 HTITKPHEEIEVKQNMKLESDMKLEKLETFLGRLNSKVPGLQEATIAVTEKSVKEVMTLDDEVFD 1354

  Fly   139 --------------------QLDDL-------LNGGPVQH-------REVQDHESQLFLSYFKNG 169
                                ..||:       |....|||       |.||..::.|.:...:..
Zfish  1355 KFYRHAEDMAKFTSRVEISDDFDDIFGVQLPRLTSEMVQHKRAVRPTRNVQSSKNPLKMLAVRED 1419

  Fly   170 IRYE----QGGVG---------------TGFKHV-----------------ETNAQGET------ 192
            ||:|    :..:|               :||..|                 ..||..::
Zfish  1420 IRHEYTEQRLNIGLLESKRMKQEKMNKNSGFSEVALAGLASKENFSSVSLRSVNASEQSSNNSAM 1484

  Fly   193 -----RLFQVKGKRNVRVRQVNLSVSSMNTGDCFILDAGSDIYVYVGSQAKRVEKLKAISAANQI 252
                 .|.||||:|:|:.|.|....||:|:||||:|......::::|..|..:||.||...|..:
Zfish  1485 PYKKLMLIQVKGRRHVQTRLVEPRASSLNSGDCFLLITPHHCFIWIGEFANVIEKAKAAELATFV 1549

  Fly   253 RDQDHNG-RAR-VQIVDDFS---TDADKQHFFDVLGSGSADQVPDESTADEDSAFERTDAAAVSL 312
            :.:...| ||. ||.:::.:   |.|.|. |:.:||..::.|  ...|.::|..:|........:
Zfish  1550 QTKHDLGCRASYVQTIEEGANTHTHAAKD-FWKILGGQTSYQ--SAGTPEQDEFYESAVVETNCI 1611

  Fly   313 YKVSDASGKLKVDIIGQKPLTQAMLDTRECFILDTGSGIFVWVGKGATQKEKTDAMAKAQEFLR- 376
            |::.:.......|..|:.|.. :||:.:|..:.|.||.::||.||..|..::..|...|:....
Zfish  1612 YRLMEDKLVPHDDYWGRVPRC-SMLNPKEVLVFDFGSEVYVWHGKEVTLAQRKVAFQLAKHLWNG 1675

  Fly   377 TKKY------------------------PAWTQIHRIVEGSESAPFKQYFDTWRDA------GMS 411
            |..|                        |.|....|:.:.:|:..||:.|..|.|:      |.|
Zfish  1676 TFDYTNCDINPLDPGECNALIPRKGQGRPDWAVFGRLTQHNETTLFKEKFLDWSDSKNSKKNGDS 1740

  Fly   412 H---------------SRLIRSALGIGSDELLNDDEIDSVVTQLKKSGGRAFGFMP-DHGQNVIE 460
            |               :.|:.||:......:|:...|           ||.:|.:. :.|:|
Zfish  1741 HVENKELRSGECRPYDASLMLSAVRAPVRTVLDGVNI-----------GRGYGLVEGEEGRN--- 1791

  Fly   461 TITQYVAKPGSDEIVVSTVPFDEKLPLLGFASYVLTYNY---------EANNGDTGSLTYV--WH 514
                         ..:||:..|        ..::|.::|         :.:.||    |||  |.
Zfish  1792 -------------FEISTLSVD--------VWHILEFDYSRLPKQSIGQFHEGD----TYVVKWK 1831

  Fly   515 GVKASAAARKRAFEEGLVG--------------------------------SKDGLLVQTNQGHE 547
             ...|.|..||...|.::|                                .:.|..||..||.|
Zfish  1832 -YMISTAVGKRLHSERIIGPGKEKCCYFFWQGRNSTVNEKGTSALMTVELDEERGAQVQVQQGKE 1895

  Fly   548 PRHFYKIFKGKLLTSFTALPVTA--------------QLFRIRGTVESDVHASEVAADSSSLASS 598
            |..|.:.|.|.::       |.|              :|:.:||....:.|..|.....|||.|.
Zfish  1896 PPCFLQCFNGGMI-------VHAGKREEEEDNTQNDWRLYCVRGEKPIEGHLLEAVCHCSSLRSR 1953

  Fly   599 DAFVLHSGKSHKIYIWNG---------LG---ASAFEKQAAVDRFSDYWDDVELEQVEEGAEPDE 651
            .:.:|.:.....:|:|:|         :|   |:..::|..::........|.:::.:|||||..
Zfish  1954 TSMILLNIPKASLYLWHGCKAQVHTRDVGRTTANKIKEQCPLEAGLHSSSKVSIQECDEGAEPQG 2018

  Fly   652 FWEELNGEGQ--YDRSLGDDGAPLLESRLFHCHLSSGGFLKVEEV-----------AQYEQEDL- 702
            |||.|....:  ||..|.|.|......|||....:||.|..||.|           ..:.||||
Zfish  2019 FWEALGKRDRKAYDCMLQDPGKFNFTPRLFQLSSASGEFAAVEFVYPSREPNLVNSMPFLQEDLY 2083

  Fly   703 --DSDDIMLLDAGDEIYLWVGYGVSEEEN-GK-----------LLDTAKLYF---NLEPTARSFD 750
              ....:.|:|...|:|||.|:...:.|: |.           .::|...|.   |.:.|.:|:
Zfish  2084 TATQPALFLVDNHHEVYLWQGWWPQDSESTGSARIRWDSDRKCAMETVLQYSKEKNEKKTPKSY- 2147

  Fly   751 TVSIIRVPQGKEPRVFKRMFPNWDDNYWQNQPSYEDMKQL 790
                 .:..|.||..|..|||:|:..        ||:.::
Zfish  2148 -----LIHAGLEPLTFTNMFPSWEHR--------EDIAEI 2174

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gel	NP_524865.2	gelsolin_S1_like	63..176	CDD:200446	34/209 (16%)
		gelsolin_S2_like	191..283	CDD:200445	33/107 (31%)
		gelsolin_S3_like	307..404	CDD:200448	26/121 (21%)
		ADF_gelsolin	470..558	CDD:472830	26/130 (20%)
		ADF_gelsolin	569..661	CDD:472830	27/117 (23%)
		gelsolin_S6_like	675..774	CDD:200447	34/127 (27%)
svila	NP_001417872.2	None