| Sequence 1: | NP_524865.2 | Gene: | Gel / 46008 | FlyBaseID: | FBgn0010225 | Length: | 798 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001139668.1 | Gene: | Scin / 20259 | MGIID: | 1306794 | Length: | 715 | Species: | Mus musculus |
| Alignment Length: | 759 | Identity: | 279/759 - (36%) |
|---|---|---|---|
| Similarity: | 405/759 - (53%) | Gaps: | 80/759 - (10%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 55 ARRVMHPSFANAGRTPGLEIWRIENFEPVIYPKTNYGKFYTGDSFIVLNTIENKKDKKLSWDVHF 119
Fly 120 WLGLETSTDEAGAAAILTVQLDDLLNGGPVQHREVQDHESQLFLSYFKNGIRYEQGGVGTGFKHV 184
Fly 185 ETNAQGETRLFQVKGKRNVRVRQVNLSVSSMNTGDCFILDAGSDIYVYVGSQAKRVEKLKAISAA 249
Fly 250 NQIRDQDHNGRARVQIVDDFSTDADKQHFFDVLGSGSADQVPDESTADEDSAFERTDAAAVSLYK 314
Fly 315 VSDASGKLKVDIIGQK-PLTQAMLDTRECFILDTGSG--IFVWVGKGATQKEKTDAMAKAQEFLR 376
Fly 377 TKKYPAWTQIHRIVEGSESAPFKQYFDTWRDAGMSHSRLIRSALGIG----SDELLNDDEIDSVV 437
Fly 438 TQLKKSGGRAFGF-MPDHGQNVIETITQYVAKPGSDEIVVSTVPFDEKLPLLGFASYVLTYNYEA 501
Fly 502 NNGDTGSLTYVWHGVKAS------AAARKRAFEEGLVGSKDGLLVQTNQGHEPRHFYKIFKGKLL 560
Fly 561 TSF----------TALPVTAQLFRIRGTVESDVHASEVAADSSSLASSDAFVLHSGKSHKIYIWN 615
Fly 616 GLGASAFEKQAAVDRFSDYWDDV---ELEQVEEGAEPDEFWEELNGEGQYDRSLGDDGAPLLES- 676
Fly 677 ------RLFHCHLSSGGFLKVEEV-AQYEQEDLDSDDIMLLDAGDEIYLWVGYGVSEEENGKLLD 734
Fly 735 TAKLYFNLEPTARSFDTVSIIRVPQGKEPRVFKRMFPNWDDNYW 778 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Gel | NP_524865.2 | gelsolin_S1_like | 63..176 | CDD:200446 | 57/112 (51%) |
| gelsolin_S2_like | 191..283 | CDD:200445 | 37/91 (41%) | ||
| gelsolin_S3_like | 307..404 | CDD:200448 | 46/99 (46%) | ||
| ADF_gelsolin | 470..558 | CDD:301701 | 24/93 (26%) | ||
| ADF_gelsolin | 569..661 | CDD:301701 | 35/94 (37%) | ||
| gelsolin_S6_like | 675..774 | CDD:200447 | 37/106 (35%) | ||
| Scin | NP_001139668.1 | Actin-severing. /evidence=ECO:0000255 | 1..363 | 162/376 (43%) | |
| gelsolin_S1_like | 10..121 | CDD:200446 | 57/112 (51%) | ||
| Polyphosphoinositide binding. /evidence=ECO:0000250 | 112..119 | 3/6 (50%) | |||
| gelsolin_S2_like | 136..225 | CDD:200445 | 38/93 (41%) | ||
| Polyphosphoinositide binding. /evidence=ECO:0000250 | 138..146 | 5/7 (71%) | |||
| gelsolin_S3_like | 246..346 | CDD:200448 | 46/99 (46%) | ||
| Ca(2+)-dependent actin binding | 364..715 | 116/379 (31%) | |||
| gelsolin_S4_like | 390..486 | CDD:200449 | 27/109 (25%) | ||
| gelsolin_S5_like | 508..598 | CDD:200444 | 36/96 (38%) | ||
| gelsolin_S6_like | 613..711 | CDD:200447 | 36/99 (36%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C167831415 | |
| Domainoid | 1 | 1.000 | 91 | 1.000 | Domainoid score | I7668 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG0443 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 461 | 1.000 | Inparanoid score | I1548 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG55329 | |
| OrthoDB | 1 | 1.010 | - | - | D1376537at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000527 | |
| OrthoInspector | 1 | 1.000 | - | - | otm43689 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100298 | |
| Panther | 1 | 1.100 | - | - | O | PTHR11977 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2540 |
| SonicParanoid | 1 | 1.000 | - | - | X232 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 15 | 14.840 | |||||