DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gel and Capg

DIOPT Version :9

Sequence 1:	NP_524865.2	Gene:	Gel / 46008	FlyBaseID:	FBgn0010225	Length:	798	Species:	Drosophila melanogaster
Sequence 2:	NP_001035999.1	Gene:	Capg / 12332	MGIID:	1098259	Length:	349	Species:	Mus musculus

Alignment Length:	352	Identity:	137/352 - (38%)
Similarity:	208/352 - (59%)	Gaps:	22/352 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 FANAGRTPGLEIWRIENFEPVIYPKTNYGKFYTGDSFIVLNTIENKKDKKLSWDVHFWLGLETST 127
            |..:.:.|||.|||:|..:||...:.::|.|::|||::||:....:..     .:|.|:|.::|.
Mouse    12 FPASVQDPGLHIWRVEKLKPVPIARESHGIFFSGDSYLVLHNGPEEAS-----HLHLWIGQQSSR 71

  Fly   128 DEAGAAAILTVQLDDLLNGGPVQHREVQDHESQLFLSYFKNGIRYEQGGVGTGFKHVETNAQGET 192
            ||.||.|:|.|.|:.||...||||||||.:||.||:|||..|::|.:|||.:.| |..|:  |.|
Mouse    72 DEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYREGGVESAF-HKTTS--GAT 133

  Fly   193 -----RLFQVKGKRNVRVRQVNLSVSSMNTGDCFILDAGSDIYVYVGSQAKRVEKLKAISAANQI 252
                 :|:|||||:|:|..:..||..|.|||||||||.|.:|:.:.|.::..:|:.||...|..|
Mouse   134 PAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAI 198

  Fly   253 RDQDHNGRARVQIVDDFSTDADKQHFFDVLGSGSADQVPDESTADEDSAFERTDAAAVSLYKVSD 317
            ||.:..|:|:|:|:.|....|:   ...|||...|.:   |...:||...::|:|.|.:||||||
Mouse   199 RDSERQGKAQVEIITDGEEPAE---MIQVLGPKPALK---EGNPEEDITADQTNAQAAALYKVSD 257

  Fly   318 ASGKLKV-DIIGQKPLTQAMLDTRECFILDTG--SGIFVWVGKGATQKEKTDAMAKAQEFLRTKK 379
            |:|::.: .:....|....:|...:||:||.|  ..|::|.|:.|.:||:..|:..|..|:...:
Mouse   258 ATGQMNLTKVADSSPFASELLIPDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVADGFISRMR 322

  Fly   380 YPAWTQIHRIVEGSESAPFKQYFDTWR 406
            |...||:..:.:|.||..|||:|..|:
Mouse   323 YSPNTQVEILPQGRESPIFKQFFKNWK 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gel	NP_524865.2	gelsolin_S1_like	63..176	CDD:200446	48/112 (43%)
		gelsolin_S2_like	191..283	CDD:200445	38/96 (40%)
		gelsolin_S3_like	307..404	CDD:200448	36/99 (36%)
		ADF_gelsolin	470..558	CDD:301701
		ADF_gelsolin	569..661	CDD:301701
		gelsolin_S6_like	675..774	CDD:200447
Capg	NP_001035999.1	gelsolin_S1_like	17..120	CDD:200446	47/107 (44%)
		gelsolin_S2_like	139..226	CDD:200445	37/89 (42%)
		gelsolin_S3_like	247..347	CDD:200448	36/99 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831417
Domainoid	1	1.000	63	1.000	Domainoid score	I10185
eggNOG	1	0.900	-	-		E1_KOG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1376537at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11977
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.850