Protein Alignment Gel and LOC100496020

DIOPT Version :10

• Sequence 1: NP_524865.2
• Gene: Gel / 46008
• FlyBaseID: FBgn0010225
• Length: 798
• Species: Drosophila melanogaster
• Sequence 2: XP_017950415.2
• Gene: LOC100496020 / 100496020
• XenbaseID: XB-GENE-29082947
• Length: 715
• Species: Xenopus tropicalis
• Alignment Length: 760
• Identity: 275/760 - (36%)
• Similarity: 401/760 - (52%)
• Gaps: 84/760 - (11%)

  Fly    58 VMHPSFANAGRTPGLEIWRIENFEPVIYPKTNYGKFYTGDSFIVLNTIENKKDKKLSWDVHFWLG 122
            |.|..|.|||:..||:|||||..:....|::.||.||.||::::||||:....|  .:.:|:|||
 Frog     3 VEHKEFVNAGKKTGLQIWRIEKMDLAPVPESFYGSFYVGDAYVILNTIDRGLYK--IYHLHYWLG 65

  Fly   123 LETSTDEAGAAAILTVQLDDLLNGGPVQHREVQDHESQLFLSYFKNGIRYEQGGVGTGFKHVETN 187
            .|.:.||:.||.|.|||||:.|.|.|||:||:|.|||..||.:||:||:|:.||:.:||:||.||
 Frog    66 NECTQDESTAAVIFTVQLDEYLGGSPVQYRELQGHESTEFLGHFKDGIKYQAGGIASGFQHVITN 130

  Fly   188 AQGETRLFQVKGKRNVRVRQVNLSVSSMNTGDCFILDAGSDIYVYVGSQAKRVEKLKAISAANQI 252
            .....||..:||:|.||..:|.||.||.|:|||||:|.|.:||.:.||::.:.|:|||...|..|
 Frog   131 DLSARRLLHIKGRRVVRATEVPLSWSSFNSGDCFIIDVGPEIYQWCGSKSNKYERLKAAQVATSI 195

  Fly   253 RDQDHNGRARVQIVDDFSTDADKQHFFDVLGSGSADQVPDESTADEDSAFERTDAAAVSLYKVSD 317
            |:.:..||:.:.:|:.||   :......:||   ...|..|...|.|...:.|:.....||.|||
 Frog   196 RNNERQGRSNLTVVEQFS---EPPSLMQILG---PMPVLPEGDDDTDVTADVTNRKMAKLYMVSD 254

  Fly   318 ASGKLKVDIIGQK-PLTQAMLDTRECFILDTG-SGIFVWVGKGATQKEKTDAMAKAQEFLRTKKY 380
            |||.::..::.:: |.:..||.:.||||||:. ..||||.||||...||..|:..|::|::...|
 Frog   255 ASGTMQTTLVSEENPFSMPMLLSDECFILDSSDKKIFVWKGKGANVNEKKHAIKTAEDFIKKMNY 319

  Fly   381 PAWTQIHRIVEGSESAPFKQYFDTWRDAGMSHSRLIRSALGIG----SDELLNDDEIDSVVTQLK 441
            ||.|||..:.||.|:..|||||..|:|...|.        |:|    .:::...::|....|:|.
 Frog   320 PATTQIIVLPEGGETPIFKQYFKDWKDKEQSE--------GLGKVFTKEQIAQIEQIPFDATKLH 376

  Fly   442 KSGGRAFGFMPDHGQNVIETITQYVAKPGSDEIVVSTVPFDEKLPL--------LGFASYVLTYN 498
            .|...|    ..|  |:::        .||..:.:..:..:.::||        .|...|::.|.
 Frog   377 TSARMA----AQH--NMLD--------DGSGHVEIWRIEKNARVPLDPETYGQFYGGDCYIIMYT 427

  Fly   499 YEANNGDTGSLTYVWHGVKASAAARKRAFEEGLVGSKDGLL----VQTN--QGHEPRHFYKIFKG 557
              ..||.  .:.|.|.|  |:|...:..:...|....|..|    .||.  ||.||.|...:||.
 Frog   428 --TLNGQ--KIIYTWQG--ANAGKDELTYSAFLTVQLDRSLKAGATQTRVPQGKEPAHLLSVFKD 486

  Fly   558 KLLTSF---------TALPVTAQLFRIRGTVESDVHASEVAADSSSLASSDAFVLHSGKSHKIYI 613
            |.|..:         .|.|...:||::|..:.|....:||.||::||.::|||||.. :.:...:
 Frog   487 KPLIIYKDGTSRKGVQAPPRPIRLFQVRKNLGSITRIAEVDADATSLNANDAFVLKM-RDNSAVM 550

  Fly   614 WNGLGASAFEKQAAVDRFSDYWDDVELEQVEEGAEPDEFWEELNGEGQYDRSLGDDGAPLLES-- 676
            |.|.||:..|.:.|  ::.....::....:.||.|||.||..|.|:..|..|      ||||:
 Frog   551 WIGKGANEDEIEGA--KYLVKVLNLRAINIAEGEEPDIFWTTLGGKKTYQTS------PLLETRL 607

  Fly   677 -----RLFHCHLSSGGFLKVEEV-AQYEQEDLDSDDIMLLDAGDEIYLWVGYGVSEEENGKLLDT 735
                 |||.|...:|.|: |||| .::.|||:..||:|:||..::|:||:|...:|.|..:.|.:
 Frog   608 EDHPPRLFGCSNKTGRFV-VEEVPGEFTQEDMAEDDVMMLDTWEQIFLWIGKDANEVEKKESLVS 671

  Fly   736 AKLYFNLEPTARSFDTVSIIRVPQGKEPRVFKRMFPNWDDNYWQN 780
            ||.|...:|:.|..| :.|..|.||.||..|...|..||.|.||:
 Frog   672 AKKYLQTDPSGRDKD-IPITTVKQGNEPLSFTGWFLAWDSNKWQD 715

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gel	NP_524865.2	gelsolin_S1_like	63..176	CDD:200446	56/112 (50%)
		gelsolin_S2_like	191..283	CDD:200445	36/91 (40%)
		gelsolin_S3_like	307..404	CDD:200448	44/98 (45%)
		ADF_gelsolin	470..558	CDD:472830	26/101 (26%)
		ADF_gelsolin	569..661	CDD:472830	30/91 (33%)
		gelsolin_S6_like	675..774	CDD:200447	40/106 (38%)
LOC100496020	XP_017950415.2	gelsolin_S1_like	8..119	CDD:200446	56/112 (50%)
		gelsolin_S2_like	136..223	CDD:200445	36/89 (40%)
		gelsolin_S3_like	244..343	CDD:200448	44/98 (45%)
		gelsolin_S4_like	387..484	CDD:200449	24/110 (22%)
		gelsolin_S5_like	507..595	CDD:200444	30/90 (33%)
		gelsolin_S6_like	611..709	CDD:200447	39/99 (39%)